PRACT-India: Practical Recommendations on Acne Care and Medical Treatment in India-A Modified Delphi Consensus.

Acne vulgaris is a prevalent dermatological condition, yet clear, region-specific management guidelines, particularly for India's diverse population, remain limited. Effective acne management extends beyond pharmacologic therapy, emphasizing proper skincare, patient education, and adherence strategies. This consensus aims to provide tailored, evidence-based recommendations for optimizing acne treatment in the Indian context.

Global diagnostic accuracy and prognostic value of non-contrast CT in acute traumatic brain injury: a systematic review and meta-analysis.

Background: Traumatic brain injury (TBI) is a global health challenge associated with high morbidity and mortality. Non-contrast computed tomography (NCCT) remains the first-line imaging modality due to its accessibility and speed, yet its diagnostic and prognostic utility across diverse populations remains underexplored.

Purpose: To systematically evaluate and quantify the diagnostic accuracy and prognostic value of NCCT in acute TBI patients worldwide.

Understanding 30-Day Mortality After First STEMI Through DAGs: Unravelling Epidemiological Cause-Effect Links.

Background And Aim: Traditional statistical tests have limitations in analyzing cause-and-effect relationships. Directed acyclic graphs (DAGs) offer a structured representation of causality. This study aimed to utilize DAGs to explore the causal impact of epidemiological factors on 30-day mortality among patients following their first acute ST-elevation myocardial infarction (STEMI).

Comparison of BlockBuster Laryngeal Mask Airway and Air-Q Intubating Laryngeal Airway as a conduit for fibreoptic bronchoscopy-guided tracheal intubation in paediatric patients: A randomised comparative study.

Background And Aims: The available supraglottic devices (SGDs) used as conduits for fibreoptic bronchoscope-guided intubation (FOI) in children have shown no difference in terms of time taken for tracheal intubation or success rate on the first attempt. However, several difficulties have been reported during the removal of the SGD after FOI. This study aimed to compare the feasibility of the safe removal of conduits after FOI through BlockBuster Laryngeal Mask Airway (BlockBuster) and Air-Q Intubating Laryngeal Airway (Air-Q) in paediatric patients.

Effect of telemonitoring and home blood pressure monitoring on blood pressure reduction in hypertensive adults: a network meta-analysis.

Introduction: Telemonitoring and home blood pressure monitoring (HBPM) are becoming popular approaches for managing hypertension. They are believed to improve patient compliance as compared to the usual care monitoring. This network meta-analysis was undertaken to compare blood pressure (BP) reduction following telemonitoring, HBPM and usual care BP monitoring approaches.

Construction and Validation of a Novel "Pruritus Impact Scale" (PIS) for Assessment of Chronic Pruritus.

Background: Currently available pruritus assessment tools may not always fulfill the needs of the Indian population and populations who share similar sociocultural backgrounds. To overcome this limitation, a new assessment tool "Pruritus Impact Scale (PIS)" was constructed and validated.

Aims And Objectives: The primary objective is to construct and validate the novel PIS.

The Reality of Evaluating Urine Spot Sodium and Urine Spot Sodium Creatinine Ratio in Furosemide Stress Test as a New Biomarker in Diagnosing Progressive AKI in Critically Ill.

Chatterjee R, Gupta L. The Reality of Evaluating Urine Spot Sodium and Urine Spot Sodium Creatinine Ratio in Furosemide Stress Test as a New Biomarker in Diagnosing Progressive AKI in Critically Ill. Indian J Crit Care Med 2024;28(12):1089-1090.

Pilot Randomized Clinical Trial of a Passive Non-invasive Positive End-Expiratory Pressure (PEEP) Device for Delivering Positive Pressure Therapy Compared to Standard Care in Non-critically Ill Patients With COVID-19.

Background: During the COVID-19 pandemic, there were reports of a shortage of ventilators and oxygen supply, particularly in resource-limited settings. We report the preliminary evaluation of a non-invasive positive end-expiratory pressure (PEEP) mask in hospitalized non-critically ill patients with COVID-19.

Methods: We randomly assigned hospitalized adult patients with confirmed COVID-19 infection and requiring greater than 40% supplemental oxygen to either standard care oxygen delivery (control) or via Materialise passive non-invasive PEEP device mask (intervention; Belgium).

Linking Generalized Ligamentous Laxity to Musculoskeletal Injury: A Study in the Indian Population.

Introduction Generalized ligamentous laxity (GLL) is defined as an increased range of motion across multiple joints in an individual beyond the mean range of motion in the general population, with a reported prevalence between 5% and 15%. It becomes less common with age and is more common in females and in the lower limbs. Musculoskeletal injury (MSI) is damage to musculoskeletal systems, usually due to strenuous activity.

Comparison of gum elastic bougie-guided insertion of LMA Protector versus the conventional method in achieving oesophagal patency - A randomised comparative study.

Background And Aims: The passage of a Ryle's tube through the drain port on the laryngeal mask airway (LMA) Protector has been reported to be arduous despite the larger gastric channel. There are no studies on the evaluation of the guided insertion of LMA Protector to achieve adequate gastrointestinal drainage function.

Methods: This randomised study included 132 patients who underwent surgery under general anaesthesia.

Comparative study of functional outcomes of arthroscopic anterior cruciate ligament reconstruction using anteromedial portal and translateral all-inside technique.

Background: Anterior Cruciate Ligament (ACL) injuries are common in the active population of the Armed Forces. Symptomatic instability prompts individuals to seek a cure or a sheltered appointment. Despite the increasing numbers of ACL reconstructions performed, the outcomes have not been so spectacular with only a meager percentage of our patients returning to preinjury levels of activity.

A Comprehensive Analysis and Review of Artificial Intelligence in Anaesthesia.

In the field of anaesthesia, artificial intelligence (AI) has become a game-changing technology. Applications of AI include keeping records, monitoring patients, calculating and administering drugs, and carrying out mechanical procedures. This article explores the current uses, challenges, and prospective applications of AI in anaesthesia practices.

Benzodiazepines Reduce Blood Pressure in Short Term: A Systematic Review and Meta-analysis.

Purpose Of Review: Benzodiazepines, due to their anxiolytic properties, are prescribed to reduce anxiety and insomnia. They might have hypotensive effect via potentiation of the inhibitory effect of gamma-amino butyric acid (GABA) in the central nervous system and vasodilatory properties. However, studies comparing the effect of benzodiazepines in lowering blood pressure (BP) are equivocal.

Multidomain Convolution Neural Network Models for Improved Event-Related Potential Classification.

Two convolution neural network (CNN) models are introduced to accurately classify event-related potentials (ERPs) by fusing frequency, time, and spatial domain information acquired from the continuous wavelet transform (CWT) of the ERPs recorded from multiple spatially distributed channels. The multidomain models fuse the multichannel Z-scalograms and the V-scalograms, which are generated from the standard CWT scalogram by zeroing-out and by discarding the inaccurate artifact coefficients that are outside the cone of influence (COI), respectively. In the first multidomain model, the input to the CNN is generated by fusing the Z-scalograms of the multichannel ERPs into a frequency-time-spatial cuboid.

Management of hereditary angioedema in resource-constrained settings: A consensus statement from Indian subcontinent.

Hereditary angioedema (HAE) is an uncommon disorder characterized clinically by recurrent episodes of nonitchy subcutaneous and/or submucosal swellings. The estimated prevalence of HAE is ~ 1: 10,000 to 1: 50,000. There are no prevalence data from India, however, estimates suggest that there are 27,000 to 135,000 patients with HAE in India at present.