Short-term effects of ambient air pollution on musculoskeletal diseases in Yangzhou during 2019-2022.

Background: Given the limited research on the association between air pollutants and musculoskeletal diseases (MDs), our study aimed to examine how exposure to air pollutants influenced the risk of developing musculoskeletal disorders.

Methods: We extracted daily air pollutants and musculoskeletal diseases data from 2019 to 2022 in Yangzhou. The combined effects of air pollutants particulate matte 2.

Fatty acid oxidation contributed to NLRP3 inflammasome activation caused by N-nitrosamines co-exposure.

Nitrosamines, as common environmental carcinogens, are closely related to the development of esophageal inflammation (EI). Studies have revealed that NLRP3 inflammasome activation was a key event in nitrosamine-induced EI. However, the involvement of fatty acid metabolism in nitrosamine-induced NLRP3 inflammasome activation has not been reported.