Joule heating is becoming accepted as a highly efficient regeneration technique for temperature vacuum swing adsorption in direct air capture (DAC). This acknowledgment arises from its ability to rapidly generate and transfer heat, along with the convenience of obtaining electrical power from renewable sources. This study presents a unique electrified fiber sorbent (i.
View Article and Find Full Text PDFThe journal's Editorial Office and Editorial Board are jointly issuing a resolution and removal of the linked to this article [...
View Article and Find Full Text PDFA high-fat diet (HFD) exerts complex effects on the risk of colitis-associated cancer (CAC). Nodakenin, a key phytochemical isolated from the dried roots of Angelicae gigas Nakai (Umbelliferae), possesses anti-inflammatory and anti-adipogenic properties and shows potential as a therapeutic agent for colorectal cancer (CRC). In this study, we investigated the protective effects and underlying molecular mechanisms of nodakenin in an animal model of CRC induced by HFD, azoxymethane (AOM), and dextran sodium sulfate (DSS).
View Article and Find Full Text PDFThe presence of nitrate (NO) in surface water and groundwater used for potable supply needs to be closely monitored since in elevated amounts it can adversely affect aquatic life and human health by causing hypoxia and methemoglobinemia. Many of the existing EPA-certified sensors used for environmental monitoring are expensive, bulky, and labor-intensive. To address these concerns, we have successfully developed a low-cost microfluidic electrochemical impedimetric sensor, consisting of a nitrate-binding nickel complex within a polyaniline/carbon nanocomposite (Ni@Pani/C) enabling nitrate monitoring in field samples.
View Article and Find Full Text PDFThis study explores how suppressing asexual development in enhances the mechanical properties of mycelial materials. Using four aconidial mutants Δ , Δ , Δ , and ) that lack asexual development and a control strain (A28) that undergoes typical asexual development, we found that the absence of asexual development significantly improves mechanical strength. All mutants exhibited higher ultimate tensile strength (UTS) than the control, with Δ and Δ (fluffy nonsporulating, FNS phenotype) showing the highest UTS.
View Article and Find Full Text PDFElectronic structure modification via intercalative electron-doping of α-RuCl, a two-dimensional (2D) transition metal halide, imparts unique optoelectronic properties such as near-infrared (NIR) absorption. While bulk-scale RuCl nanosheet production has been established using conventional liquid phase exfoliation, printed devices compatible with scalable manufacturing remain unexplored. Here, we demonstrate fully aerosol-jet-printed (AJP) NIR photodetectors based on megasonically processed RuCl nanosheets.
View Article and Find Full Text PDFMorphotaxy, a process by which a 2D material is chemically modified while retaining its original physical dimensions, is an emerging strategy for synthesizing unconventional materials at the atomically thin limit. Morphotaxy is typically implemented by vapor-phase reactions on mechanically exfoliated or vapor-deposited 2D van der Waals (vdW) materials. Here we report a method for converting solution-processed films of 2D InSe into InI and InBr using dilute I and Br solutions, respectively.
View Article and Find Full Text PDFJ Enzyme Inhib Med Chem
December 2025
β-lactams have been the most successful antibiotics, but the rise of multi-drug resistant (MDR) bacteria threatens their effectiveness. Serine β-lactamases (SBLs), among the most common causes of resistance, are classified as A, C, and D, with numerous variants complicating structural and substrate spectrum comparisons. This study compares representative SBLs of these classes, focusing on the substrate-binding pocket (SBP).
View Article and Find Full Text PDFFungal Biol Biotechnol
December 2024
Mycelial materials are an emerging, natural material made from filamentous fungi that have the potential to replace unsustainable materials used in numerous commercial applications (e.g., packaging, textiles, construction).
View Article and Find Full Text PDFUnlabelled: This study investigates a previously unreported stress signal transduced as crosstalk between the cell wall integrity (CWI) pathway and the septation initiation network (SIN). Echinocandins, which target cell wall synthesis, are widely used to treat mycoses. Their efficacy, however, is species specific.
View Article and Find Full Text PDFMicrobiol Resour Announc
January 2025
We announce the complete genome of strain PEC1003 belonging to ST7366, isolated from sewage water in Pakistan. This strain harbored a plasmid carrying various antibiotic resistance genes, including extended-spectrum β-lactamase (ESBL), , emphasizing the management and surveillance of ESBL-producing in the environment of developing countries.
View Article and Find Full Text PDFMicrobiol Resour Announc
November 2024
We present the complete genome sequence of strain PEC1009 isolated from avian feces in Pakistan. The strain belongs to sequence type (ST) 10, a high-risk clone. The strain possesses two plasmids, and various plasmid-borne antibiotic resistance genes and chromosome-borne virulence factor genes were identified in its genome.
View Article and Find Full Text PDFEmerg Microbes Infect
December 2024
In the pursuit of achieving high-performance and high-throughput organic transistors, this study highlights two critical aspects: designing new soluble acenes and optimizing their solution processing. A fundamental understanding of the crystallization mechanism inherent to these customized soluble acenes, as they undergo a transformation during the evaporation of residual solvent, is deemed essential. Here, the pathway to crafting ideal solution processing conditions is elucidated, meticulously tailored to the molecular structure of soluble acenes when blended with polymers.
View Article and Find Full Text PDFJ Microbiol Biotechnol
October 2024
The emergence and spread of multidrug-resistance (MDR) pathogenic due to horizontal gene transfer of antibiotic resistance genes (ARGs) and virulence factors (VFs) is a global health concern, particularly in developing countries. While numerous studies have focused on major sequence types (STs), the implication of minor STs in ARG dissemination and their pathogenicity remains crucial. In this study, two strains (PEC1011 and PEC1012) were isolated from wild bird feces in Pakistan and identified as ST2178 based on their complete genome sequences.
View Article and Find Full Text PDFBioengineering (Basel)
August 2024
Cardiovascular disease is a major global health concern, with early detection being critical. This study assesses the effectiveness of a portable ECG device, based on Internet of Medical Things (IoMT) technology, for remote cardiovascular monitoring during daily activities. We conducted a clinical trial involving 2000 participants who wore the HiCardi device while engaging in hiking activities.
View Article and Find Full Text PDF(FR), a perennial flower of the Iris family (Iridaceae), is widely used in cosmetics despite limited scientific evidence of its skin benefits and chemical composition, particularly of FR callus extract (FCE). This study identified biologically active compounds in FCE and assessed their skin benefits, focusing on anti-aging. FR calli were cultured, extracted with water at 40 °C, and analyzed using Centrifugal Partition Chromatography (CPC), Nuclear Magnetic Resonance (NMR), and HCA, revealing key compounds, namely nicotinamide and pyroglutamic acid.
View Article and Find Full Text PDFA unified diagnostic criterion has yet to be established for sarcopenia. Therefore, we analyzed the reliability and validity of sarcopenia diagnosis using bioelectrical impedance analysis (BIA) compared with the gold standard, dual-energy X-ray absorptiometry (DEXA), and evaluated the predictive accuracy of BIA for diagnosis. The clinical trial, involving a total of 239 participants, was conducted between December 2018 and September 2019 on healthy volunteers without significant medical histories.
View Article and Find Full Text PDFJ Microbiol Biotechnol
June 2024
The environment has been identified as an origin, reservoir, and transmission route of antibiotic resistance genes (ARGs). Among diverse environments, freshwater environments have been recognized as pivotal in the transmission of ARGs between opportunistic pathogens and autochthonous bacteria such as spp. In this study, five environmental strains of spp.
View Article and Find Full Text PDFJ Enzyme Inhib Med Chem
December 2024
The urgent demand for effective countermeasures against metallo-β-lactamases (MBLs) necessitates development of novel metallo-β-lactamase inhibitors (MBLIs). This study is dedicated to identifying critical chemical moieties within previously developed MBLIs, and critical MBLs should serve as the target in MBLI evaluations. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), a systematic literature analysis was conducted, and the NCBI RefSeq genome database was exploited to access the abundance profile and taxonomic distribution of MBLs and their variant types.
View Article and Find Full Text PDFEur J Phys Rehabil Med
April 2024
Background: Appropriate evaluation and management of dysphagia are essential in neurological disorders. However, there is currently a lack of a simple yet reliable method for dysphagia evaluation.
Aim: This study aimed to investigate the usefulness of new dynamic M-mode ultrasonography (US) parameters of suprahyoid muscle (SHM) to evaluate dysphagia.
J Am Heart Assoc
January 2024
Background: Epinephrine is administered to increase coronary perfusion pressure during advanced life support and promote short-term survival. Recent cardiopulmonary resuscitation (CPR) guidelines recommend an epinephrine dosing interval of 3 to 5 minutes during resuscitation; however, scientific evidence supporting this recommendation is lacking. Therefore, we aimed to investigate the hemodynamic effects of repeated epinephrine doses during CPR by monitoring augmented blood pressure after its administration in a swine model of cardiac arrest.
View Article and Find Full Text PDFis the primary opportunistic human pathogen responsible for a range of acute and chronic infections; it poses a significant threat to immunocompromised patients and is the leading cause of morbidity and mortality for nosocomial infections. Its high resistance to a diverse array of antimicrobial agents presents an urgent health concern. Among the mechanisms contributing to resistance in , the horizontal acquisition of antibiotic resistance genes (ARGs) via mobile genetic elements (MGEs) has gained recognition as a substantial concern in clinical settings, thus indicating that a comprehensive understanding of ARG dissemination within the species is strongly required for surveillance.
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