Response of intertidal fucales to low-tide heat stress at their southern distributional limit.

The increasing intensity and frequency of atmospheric heatwaves threaten the physiological capabilities of intertidal canopy-forming macroalgae, especially at their southern range, where species live closer to their upper thermal limits. While heat stress experiments on these species are increasingly common, few incorporate realistic intertidal conditions. This study assessed the physiological responses of key intertidal macroalgae across the intertidal range (Fucus serratus, Fucus spiralis, Ascophyllum nodosum, and Pelvetia canaliculata), at their southern distribution limit in the NW Iberian Peninsula to simulate heat stress using a custom setup that replicated realistic conditions, including tidal cycles and temperature patterns.

Effect of Comorbidities on the Mortality of Patients With COVID-19: A Systematic Review of Reviews and Meta-Analyses.

Studies with strong scientific evidence have demonstrated that comorbidities are associated with fatal outcomes in patients with SARS-CoV-2 infection. To aggregate the findings of these studies and assess the magnitude of the effect of different chronic diseases on COVID-19 mortality, we conducted a systematic review of reviews and meta-analysis. Six databases were searched to retrieve systematic reviews with meta-analysis published during the early years of the pandemic.

Hypertension induced by peri-pubertal protein restriction depends on renin-angiotensin system dysfunction in adult male rats.

Background And Aims: Hypertension depends on renin-angiotensin system dysfunction; however, little is known about its implications in the outcomes of neurogenic hypertension induced by peri-pubertal insults. This study aimed to evaluate whether hypertension induced by a peri-pubertal low-protein diet is related to renin-angiotensin system dysfunction in adult male Wistar rats.

Methods And Results: Thirty-day-old male Wistar rats were fed a low-protein diet (4 % casein) for 30 days and subsequently fed a 20.

Envelope Protein in Differential Serodiagnosis of Dengue, Zika and Chikungunya Viruses: A Systematic Review.

Objectives: This systematic review was conducted to evaluate the applicability of the envelope (E) protein in the diagnosis of arboviruses.

Methods: This review was performed in accordance with the PRISMA statement. Five databases were explored (PubMed, Web of Science, Scopus, EMBASE, and IEDB).

Progesterone and brassinosteroids synergistically enhance progesterone removal and antioxidant capacity of L.

Progesterone (PROG) has been detected at various concentrations in the environment and has adverse effects on humans and wildlife. This work evaluated the impact of PROG in L. plants, its removal capacity, and how 2,4-epibrassinolide (24-EBL) affects this process.

Mortality of Young Women due to Breast Cancer in Low, Middle and High-Income Countries: Systematic Literature Review and Meta-Analysis.

Objective: To identify the difference in breast cancer mortality rates among young women according to countries' economic classification.

Methods: A systematic literature review included retrospective studies on breast cancer mortality rates in women aged 20 to 49 years. Databases used were PubMed, Web of Science, Scopus, and Virtual Health Library, with articles selected in English, Portuguese, and Spanish.

Aesthetic assessment instrument for breasts reconstruction.

Introduction: Few validated aesthetic assessment instruments in breast reconstruction use discrete scales to facilitate studies with multiple evaluators.

Objective: This research aimed to propose an aesthetic assessment scale for reconstructed breasts.

Methodology: A scale was suggested using discrete variables, with responses ranging from 1 to 10, and the responses for each category could be summed to obtain an average that could be used in studies with multiple evaluators.

Acute viral bronchiolitis phenotype in response to glucocorticoid and bronchodilator treatment.

Objective: To analyze whether infants admitted to hospital with Acute Viral Bronchiolitis (AVB), who received glucocorticoids and bronchodilators, and who had an atopic phenotype, spent less time in hospital and/or less time on oxygen therapy when compared to those who did not have the phenotype.

Method: A cross-sectional, retrospective epidemiological study was developed with data from medical records of infants admitted to hospital due to AVB from 2012 to 2019 in a sentinel public hospital. It was verified that the frequency of prescription of glucocorticoids, bronchodilators and antibiotics.

Statistical heterogeneity in meta-analysis of hypertension and exercise training: A meta-review.

We aim to evaluate the prevalence of reporting and the extent of statistical heterogeneity of systematic reviews with meta-analyses (SRMAs) of exercise training for hypertension and to provide practical recommendations for dealing with statistical heterogeneity. We systematically searched on four databases (from 2002 to September of 2023) for SRMAs comparing exercise interventions vs. a non-exercise control on blood pressure (BP) control in adults with hypertension.

Fungicides as a risk factor for the development of neurological diseases and disorders in humans: a systematic review.

Although studies show that pesticides, especially insecticides, may be toxic to humans, publications on the neurological effects of fungicides are scarce. As fungicides are used widely in Brazil, it is necessary to gather evidence to support actions aimed at safely using of these chemicals. We investigated through a systematic review of publications on the use of fungicides and consequences of exposure related to nervous system diseases or neurological disorders in humans.

Recreational futsal provides broad-spectrum fitness and health benefits but no blood pressure effects in men with treated hypertension - a randomised controlled trial.

We determined the coadjuvant effect of a recreational futsal (RF) programme versus standard care alone (CON) in men with treated arterial hypertension (TAHT). Thirty-nine men with TAHT were randomised to RF ( = 20; 48 ± 8 years; systolic blood pressure [SBP]: 122 ± 14 mmHg) with 2-3 one-hour sessions/week for 3 months, or to CON ( = 19; 51 ± 6 years; SBP: 126 ± 13 mmHg). Participants were assessed at baseline, at 3 months, and after 1 month of training cessation (4 months).

Laser-Modified Ti Surface Improves Paracrine Osteogenesis by Modulating the Expression of DKK1 in Osteoblasts.

Titanium surface modifications are widely used to modulate cellular behavior by recognition of topographical cues. However, how those modifications affect the expression of mediators that will influence neighboring cells is still elusive. This study aimed to evaluate the effects of conditioned media from osteoblasts cultured on laser-modified titanium surfaces on the differentiation of bone marrow cells in a paracrine manner and to analyze the expression of Wnt pathway inhibitors.

Combination of Conventional Drugs with Biocompounds Derived from Cinnamic Acid: A Promising Option for Breast Cancer Therapy.

Despite the options available for breast cancer (BC) therapy, several adverse effects and resistance limit the success of the treatment. Furthermore, the use of a single drug is associated with a high failure rate. We investigated through a systematic review the in vitro effects of the combination between conventional drugs and bioactive compounds derived from cinnamic acid in BC treatment.

Lumbosacral plexus block using a combination of ultrasound-guided lateral pre-iliac and parasacral approaches in cats.

Objective: To describe an ultrasound-guided lateral pre-iliac (LPI) and parasacral (PS) approach in feline cadavers (phase I) and compare the perioperative analgesic use and complications in cats administered LPI and PS blocks (group PNB) or epidural anesthesia (group EPI) for pelvic limb surgery (phase II).

Study Design: Experimental uncontrolled, anatomic and retrospective cohort study.

Animals: A group of eight feline cadavers and 52 medical records.

Intermittent high-intensity exercise for pre- to established hypertension: A systematic review and meta-analysis.

Objective: To determine the impact of intermittent high-intensity exercise training ([IHIE], including high-intensity interval training [HIIT] and recreational team sports [RTS]) on systolic (SBP) and diastolic blood pressure (DBP) in adults with pre- to established arterial hypertension.

Data Sources: MEDLINE, Cochrane Library, Embase, and SPORTDiscus.

Eligibility Criteria: Randomized controlled trials (RCTs) comparing the impact of IHIE on BP versus a non-exercise control.

Ultrasound Assessment in a Pregnant Woman? Not just for the Fetus.

Pericarditis is a relatively common diagnosis worldwide; however, there are few data published on the frequency, diagnosis, and management of pericardial diseases in pregnant women. Ultrasonography has established its utmost importance and is worldwide recognized in pregnancy and fetal evaluation. Moreover, point-of-care ultrasonography of pregnant women, guided by clinical examination and history, can play an equally fundamental role.

Subcellular compartmentalization of aluminum reduced its hazardous impact on rye photosynthesis.

Aluminum (Al) toxicity limits crops growth and production in acidic soils. Compared to roots, less is known about the toxic effects of Al in leaves. Al subcellular compartmentalization is also largely unknown.

Computational method for aid in the diagnosis of sixth optic nerve palsy through digital videos.

The sixth cranial nerve, also known as the abducens nerve, is responsible for controlling the movements of the lateral rectus muscle. Palsies on the sixth nerve prevent some muscles that control eye movements from proper functioning, causing headaches, migraines, blurred vision, vertigo, and double vision. Hence, such palsy should be diagnosed in the early stages to treat it without leaving any sequela.

Erector spinae plane block at the thoracolumbar spine: a canine cadaveric study.

Objective: To investigate the injectate spread and nerve staining of ultrasound-guided erector spinae plane (ESP) injections at the thoracolumbar spine in canine cadavers.

Study Design: Prospective, randomized, descriptive, anatomic study.

Animals: A total of 15 canine cadavers.

Portuguese translation, cross-cultural adaptation and reliability of Young Spine Questionnaire.

Objective: To translate and perform the cross-cultural adaptation of the Young Spine Questionnaire (YSQ) into Portuguese, and to assess its reliability.

Method: Translation and cross-cultural adaptations were conducted according to accepted international standards. A preliminary version underwent pilot-testing with 32 children (11-14 years), equally divided by gender and age.

Aesthetic assessment of breast reconstruction in the eyes of plastic surgeons versus nonplastic physicians.

Objective: The aim of this study was to evaluate the perception of the aesthetic result of breast reconstruction surgery from the perspective of plastic surgeons compared with physicians who are not specialists in plastic surgery.

Methods: Twenty patients who underwent breast reconstruction after mastectomy had their aesthetic results evaluated by 16 plastic surgeons and 16 nonplastic physicians, yielding a total of 620 ratings (320 ratings from plastic surgeons and 320 ratings from other specialists). For all analyses, the level of rejection adopted for the null hypothesis was 5% (p-value <0.

Asymptomatic Neurosyphilis in HIV infected patients at a Brazilian HIV and AIDS specialized service: a cross sectional study.

Background: Many human immunodeficiency virus (HIV) and syphilis co-infected patients are not diagnosed, which may evolve into asymptomatic neurosyphilis (ANS). We studied the occurrence of ANS an HIV-infected population.

Methods: This was a cross-sectional study of cerebrospinal fluid (CSF) samples collected from patients co-infected with HIV and Treponema pallidum.