Exploring the role of diet quality and adiposity in the pain experience: a mediation analysis.

Purpose: Improving diet quality may lower chronic musculoskeletal pain (CMP) directly or through weight loss. This study examined whether a dietary intervention for weight-loss improved diet quality and CMP in adults with elevated adiposity. It also investigated whether adiposity mediated a relationship between diet quality and pain.

Effect of work-to-rest ratio on acute responses to repeated-sprint training in hypoxia in elite track endurance cyclists.

Repeated-sprint training in hypoxia (RSH) is increasingly used by athletes to improve repeat sprint ability in normoxia. However, the physiological responses to varying protocols remain unclear. This study aimed to determine how different RSH protocols affect acute physiological responses in elite cyclists.

Exploiting the vulnerability of SARS-CoV-2 with a partnership of mucosal immune function and nutrition: a narrative review.

To achieve infectivity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, must first traverse the upper respiratory tract mucosal barrier. Once infection is established, the cascading complexities of the pathophysiology of COVID-19 makes intervention extremely difficult. Thus, enhancing the defensive properties of the mucosal linings of the upper respiratory tract may reduce infection by SARS-CoV-2 and indeed by other viruses such as influenza, which have been responsible for the two major pandemics of the last century.

Impact of dietary cholesterol from eggs and saturated fat on LDL cholesterol levels: a randomized cross-over study.

Background: Cardiovascular disease (CVD) remains a leading cause of death. Although dietary cholesterol from eggs has been a focus of dietary guidelines, recent evidence suggests that saturated fat has a greater impact on LDL cholesterol.

Objectives: This study examined the independent effects of dietary cholesterol and saturated fat on LDL concentrations.

Polyphenol-Rich Snack Consumption during Endurance Exercise Training Improves Nitric Oxide Bioavailability but does not Improve Exercise Performance in Male Cyclists: A Randomised Controlled Trial.

Background: Antioxidants and nitric oxide (NO) precursors may improve endurance exercise performance by reducing oxidative stress and increasing NO production. Almonds, dried grapes, and cranberries (AGC) are good sources of antioxidants and NO precursors.

Objectives: To determine whether AGC consumption improved physiological responses and endurance cycling time-trial performance in response to training.

The Cumulative Impacts of Fatigue during Overload Training Can Be Tracked Using Field-Based Monitoring of Running Stride Interval Correlations.

Integrating running gait coordination assessment into athlete monitoring systems could provide unique insight into training tolerance and fatigue-related gait alterations. This study investigated the impact of an overload training intervention and recovery on running gait coordination assessed by field-based self-testing. Fifteen trained distance runners were recruited to perform 1-week of light training (baseline), 2 weeks of heavy training (high intensity, duration, and frequency) designed to overload participants, and a 10-day light taper to allow recovery and adaptation.

Optimizing Wearable Device and Testing Parameters to Monitor Running-Stride Long-Range Correlations for Fatigue Management in Field Settings.

Purpose: There are important methodological considerations for translating wearable-based gait-monitoring data to field settings. This study investigated different devices' sampling rates, signal lengths, and testing frequencies for athlete monitoring using dynamical systems variables.

Methods: Secondary analysis of previous wearables data (N = 10 runners) from a 5-week intensive training intervention investigated impacts of sampling rate (100-2000 Hz) and signal length (100-300 strides) on detection of gait changes caused by intensive training.

A Mediterranean Diet and Walking Intervention to Reduce Cognitive Decline and Dementia Risk in Independently Living Older Australians: The MedWalk Randomized Controlled Trial Experimental Protocol, Including COVID-19 Related Modifications and Baseline Characteristics.

Background: Several clinical trials have examined diet and physical activity lifestyle changes as mitigation strategies for risk factors linked to cognitive decline and dementias such as Alzheimer's disease. However, the ability to modify these behaviors longer term, to impact cognitive health has remained elusive.

Objective: The MedWalk trial's primary aim is to investigate whether longer-term adherence to a Mediterranean-style diet and regular walking, delivered through motivational interviewing and cognitive-behavioral therapy (MI-CBT), can reduce age-associated cognitive decline and other dementia risk factors in older, independently living individuals without cognitive impairment.

Effects of Cold-Water Immersion Compared with Other Recovery Modalities on Athletic Performance Following Acute Strenuous Exercise in Physically Active Participants: A Systematic Review, Meta-Analysis, and Meta-Regression.

Background: Studies investigating the effects of common recovery modalities following acute strenuous exercise have reported mixed results.

Objectives: This systematic review with meta-analysis and meta-regression compared the effects of cold-water immersion (CWI) against other common recovery modalities on recovery of athletic performance, perceptual outcomes, and creatine kinase (CK) following acute strenuous exercise in physically active populations.

Study Design: Systematic review, meta-analysis, and meta-regression.

Longitudinal haematological responses to training load and heat acclimation preceding a male team pursuit cycling world record.

This study evaluated relationships between changes in training load, haematological responses, and endurance exercise performance during temperate and heat acclimation (HA) training preceding a male team cycling pursuit world record (WR). Haemoglobin mass (Hb) and concentration ([Hb]), plasma volume (PV) and blood volume (BV) were assessed in nine male track endurance cyclists (∼3 occasions per month) training in temperate conditions (247-142 days prior to the WR) to establish responses to differing acute (ATL) and chronic (CTL) training loads. Testing was performed again pre- and post-HA (22-28 days prior to the WR).

Potential methylation-regulated genes and pathways in hepatocellular neoplasm, not otherwise specified.

Background And Aims: The molecular basis of hepatocellular neoplasm, not otherwise specified (HCN-NOS) is unknown. We aimed to identify gene expression patterns, potential methylation-regulated genes and pathways that characterize the tumor, and its possible relationship to hepatoblastoma and hepatocellular carcinoma (HCC).

Approach & Results: Parallel genome-wide profiling of gene expression (RNAseq) and DNA methylation (EPIC850) was performed on 4 pairs of pre-treatment HCN-NOS tumors and adjacent non-tumor controls.

A Food Relief Charter for South Australia-Towards a Shared Vision for Pathways Out of Food Insecurity.

Chronic food insecurity persists in high-income countries, leading to an entrenched need for food relief. In Australia, food relief services primarily focus on providing food to meet immediate need. To date, there has been few examples of a vision in the sector towards client outcomes and pathways out of food insecurity.

Sport Participation and Subjective Outcomes of Health in Middle-Aged Men: A Scoping Review.

Although sport participation is intrinsically motivating and improves the physical health of middle-aged men, its influence on subjective health measures, such as health-related quality of life, self-rated health, or well-being is unclear. The purpose of this scoping review was to describe the existing literature that has assessed male sport participants and their subjective health. MEDLINE, Embase, Emcare, PsycInfo, SPORTDiscus, Cochrane Library, and Web of Science were searched, and reference lists of included studies were pearled.

Impact of Cold-Water Immersion Compared with Passive Recovery Following a Single Bout of Strenuous Exercise on Athletic Performance in Physically Active Participants: A Systematic Review with Meta-analysis and Meta-regression.

Background: Studies investigating the effects of cold-water immersion (CWI) on the recovery of athletic performance, perceptual measures and creatine kinase (CK) have reported mixed results in physically active populations.

Objectives: The purpose of this systematic review was to investigate the effects of CWI on recovery of athletic performance, perceptual measures and CK following an acute bout of exercise in physically active populations.

Study Design: Systematic review with meta-analysis and meta-regression.

Markers of Cardiac Autonomic Function During Consecutive Day Peak Exercise Tests in People With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) have been shown to exhibit altered ventilatory characteristics on the second of two progressive maximal cardiopulmonary exercise tests (CPET) performed on consecutive days. However, maximal exercise can exacerbate symptoms for ME/CFS patients and cause significant post-exertional malaise. Assessment of heart rate (HR) parameters known to track post-exertional fatigue may represent more effective physiological markers of the condition and could potentially negate the need for maximal exercise testing.

Randomised controlled trial comparing two group-based exercise programmes (team sport vs circuit training) on men's health: study protocol.

Introduction: Physical activity promotes physical, psychological and social health. Despite this, almost half of middle-aged (35-54 years) Australian men are insufficiently active. Exercise adherence is increased with social interaction in a group setting.

Heart-Rate Acceleration Is Linearly Related to Anaerobic Exercise Performance.

Purpose: To prescribe training loads to improve performance, one must know how an athlete is responding to loading. The maximal rate of heart-rate increase (rHRI) during the transition from rest to exercise is linearly related to changes in endurance exercise performance and can be used to infer how athletes are responding to changes in training load. Relationships between rHRI and anaerobic exercise performance have not been evaluated.

Effects of very low-carbohydrate vs. high-carbohydrate weight loss diets on psychological health in adults with obesity and type 2 diabetes: a 2-year randomized controlled trial.

Aims: Very low-carbohydrate (LC) diets are popular for type 2 diabetes (T2DM) management; however, long-term effects on psychological health remain largely unknown. This study reports the effects of a LC diet on mood and cognitive function after 2 years and explores the potential predictors of changes in psychological health.

Methods: 115 adults (57% males; age: 58.