Publications by authors named "Alison M Coates"

Purpose: Improving diet quality may lower chronic musculoskeletal pain (CMP) directly or through weight loss. This study examined whether a dietary intervention for weight-loss improved diet quality and CMP in adults with elevated adiposity. It also investigated whether adiposity mediated a relationship between diet quality and pain.

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Study Objectives: Cortisol regulates various physiological systems and exhibits a circadian rhythm influenced by sleep-wake and light-dark cycles. The cumulative effects of consecutive night shifts and nighttime eating on cortisol dynamics are not well understood. This sub-study of a larger randomised controlled trial aimed to explore these relationships.

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Background: Weight gain and an increased risk of developing type 2 diabetes are recognised consequences of night shift work. We tested the effectiveness of two modified intermittent fasting (IF) strategies compared with continuous energy restriction (CER) on weight loss and improvements in insulin resistance in night shift workers.

Methods: A parallel group, three-arm randomised superiority clinical trial (Melbourne and Adelaide) recruited night shift workers (aged ≥ 25 and ≤ 65 years) with overweight/obesity.

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Background: Cardiovascular disease (CVD) remains a leading cause of death. Although dietary cholesterol from eggs has been a focus of dietary guidelines, recent evidence suggests that saturated fat has a greater impact on LDL cholesterol.

Objectives: This study examined the independent effects of dietary cholesterol and saturated fat on LDL concentrations.

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Background: Antioxidants and nitric oxide (NO) precursors may improve endurance exercise performance by reducing oxidative stress and increasing NO production. Almonds, dried grapes, and cranberries (AGC) are good sources of antioxidants and NO precursors.

Objectives: To determine whether AGC consumption improved physiological responses and endurance cycling time-trial performance in response to training.

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Context: Nut consumption is attributed to improvements in risk factors for cardiovascular disease (CVD), including high blood pressure (BP) and dyslipidemia. However, it is unclear whether these effects are altered with concurrent treatment with BP and lipid-lowering medication.

Objective: We sought to investigate the effects of the consumption of whole tree nuts and peanuts (collectively termed nuts) on BP and lipids, and whether BP and lipid-lowering medication use alters these effects.

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Temporal patterns of eating and diet composition are influenced by factors including circadian preference (chronotype) and work schedule, yet their combined influence is unknown. We investigated relationships between chronotype, temporal eating patterns (duration of eating window (DEW), time of first (FEO) and last (LEO) eating occasions), and diet composition on workdays (WD) and work-free days (FD). Non-shift workers ( = 39) completed the Chrononutrition Questionnaire (CNQ) (age: 38.

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Objectives: The relationship between nut intake and disability-free survival (healthy lifespan) in later life is unclear. The objective was to evaluate the association between nut intake and disability-free survival in a cohort of adults aged ≥70 years, and whether this varied according to overall diet quality.

Methods: This prospective cohort study involved 9916 participants from the ASPREE Longitudinal Study of Older Persons.

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Aims/hypothesis: Night-shift work causes circadian misalignment and impairs glucose metabolism. We hypothesise that food intake during night shifts may contribute to this phenomenon.

Methods: This open-label, multi-arm, single-site, parallel-group controlled trial involved a 6 day stay at the University of South Australia's sleep laboratory (Adelaide, SA, Australia).

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Article Synopsis
  • - The study explored how dietary intake relates to pain and physical function, investigating whether this relationship is influenced by factors like body mass index (BMI), waist circumference, or body fat in a group of 654 participants (57% women).
  • - It found that while better diet quality (measured by the Dietary Guidelines Index) was linked to lower bodily pain, adiposity did not mediate this connection, meaning diet quality directly affects pain levels regardless of body weight.
  • - The results suggest that maintaining a good diet may play a significant role in managing pain and enhancing physical function, particularly in women.
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Study Objectives: This protocol paper outlines the methods that will be used to examine the impact of altering meal timing on metabolism, cognitive performance, and mood during the simulated night shift.

Methods: Participants (male and female) will be recruited according to an a priori selected sample size to complete a 7-day within and between participant's laboratory protocol. Participants will be randomly assigned to one of the three conditions: meal at night or snack at night or no meal at night.

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Article Synopsis
  • * After a 3-month dietary intervention, participants lost an average of 7 kg and showed improvements in functional mobility, with a significant reduction in the prevalence of CMP and multisite pain.
  • * No improvements in systemic inflammation were observed; however, changes in pain levels were not directly linked to the amount of weight lost, indicating that factors beyond weight loss may influence pain reduction.
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The irregular eating patterns of both shift workers and evening chronotypes adversely affect cardiometabolic health. A tool that conveniently captures temporal patterns of eating alongside an indicator of circadian rhythm such as chronotype will enable researchers to explore relationships with diverse health outcome measures. We aimed to investigate the test-retest reliability and convergent validity of a Chrononutrition Questionnaire (CNQ) that captures temporal patterns of eating and chronotype in the general population (non-shift workers, university students, retirees, unemployed individuals) and shift work population.

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  • A review of randomised controlled trials found 7 studies focused on the impact of ER diets with or without nuts on weight, body composition, and glycaemic control in adults.
  • While all studies showed weight loss with ER diets, only about half found that adding nuts significantly enhanced weight loss, and there was limited evidence for additional benefits regarding body composition or blood sugar control; however, no negative health effects were linked to nut consumption.
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  • Previous research suggested that high dietary cholesterol raises LDL cholesterol and increases cardiovascular disease risk, but new studies indicate saturated fat may be more to blame; eggs, despite being high in cholesterol, are low in saturated fat and may not negatively impact health.* -
  • This paper outlines a study involving 52 adults who will follow three different diets, comparing the effects of high-cholesterol/low-saturated fat (egg diet), low-cholesterol/high-saturated fat (egg-free diet), and a control diet on their blood lipid levels and lipoproteins over a 15-week period.* -
  • The study will assess how physical activity influences blood lipids and examine any changes in blood levels of lutein and zeaxanth
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Article Synopsis
  • The study aims to investigate how dietary patterns and lifestyle behaviors impact individuals suffering from chronic musculoskeletal pain, focusing on those who experience pain for at least 3 months.
  • Participants will undergo two clinic visits to take physical measurements and complete questionnaires, alongside a 2-week self-monitoring phase where they track their diet, sleep, mood, and pain levels.
  • The research seeks to enhance understanding of the role of diet in managing chronic pain, with findings intended to improve future dietary interventions for those affected.
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  • This study compared the effects of an almond-enriched diet (AED) with a carbohydrate-rich snack diet (nut-free control diet, NFD) on weight and cardiometabolic health over 9 months.
  • Participants aged 25-65 with a BMI between 27.5-34.9 lost similar amounts of weight during the first 3 months, with both diets resulting in significant health improvements, such as lower blood pressure and better cholesterol levels.
  • The AED produced greater positive changes in specific lipoprotein particles compared to the NFD, suggesting potential benefits for heart health, while both diets support effective weight management.
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Diet quality often changes as shift workers adjust to atypical work schedules, however, limited research exists examining the early effects of starting rotating shift work on diet and body composition. This study explored dietary behavior changes occurring in graduate paramedics during the first year of exposure to rotating shift work, and investigated dietary intake, diet quality and anthropometric changes over two years. Participants from a graduate paramedic cohort in Melbourne, Australia were approached after two years of shift work for study inclusion.

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Article Synopsis
  • - Recent evidence since 2018 on the link between egg consumption and cardiovascular disease (CVD) shows mixed results, with some studies suggesting increased risk of CVD mortality while others find no significant association.
  • - Most observational studies indicate that egg intake does not worsen CVD risk factors and may even reduce risk, but high egg consumption habits vary significantly across different ethnic groups.
  • - Given the inconsistency in findings, dietary advice should prioritize overall diet quality rather than focusing solely on egg consumption to enhance cardiovascular health.
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The negative impact of an unhealthy diet on the shiftworker population has been well-documented. However, little evidence exists on the underlying reasons for unhealthy eating behaviours and the existing barriers to healthy eating withinshiftwork environments. This qualitative study investigated the dietary behaviours reported by shiftworkers through Facebook comments.

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Workers employed in rotating shift schedules are at a higher metabolic risk compared with those in regular day and fixed shift schedules; however, the contribution of diet is unclear. This systematic review aimed to investigate how rotating shift work schedules affect dietary energy intake and dietary patterns compared with regular day and fixed shift schedules. In addition, intraperson energy intake and dietary pattern comparisons within rotating shift schedules were investigated.

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Article Synopsis
  • The study explores how consuming almonds (AL) influences appetite-regulating hormones and self-reported appetite compared to a carbohydrate-rich snack bar (SB) in overweight and obese adults.
  • Results showed that post-meal hormonal responses were more favorable after eating almonds, with a significantly lower C-peptide response and increased levels of insulinotropic hormones.
  • Despite the hormonal differences favoring almonds, both groups reported similar appetite levels and energy intake after a buffet meal, suggesting future research is needed on long-term appetite effects.
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  • The study investigated dietary changes among breast cancer survivors with ongoing cognitive challenges, focusing on factors influencing these changes and barriers faced in adopting healthier eating habits.
  • Thirteen Australian survivors participated in interviews, revealing themes like changes in meal timing, increased plant-based foods, and a shift towards convenience eating, as well as various reasons for these changes such as treatment effects and support from others.
  • Barriers to intentional dietary modifications included time constraints, cravings for certain foods, and a lack of resources or ideas for healthy meals, highlighting the complexity of maintaining dietary changes post-cancer treatment.
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Purpose Of Review: The aim of this short review is to provide an updated commentary on the current literature examining the impact of meal timing on obesity and weight gain in adults. The potential mechanisms, including novel and emerging factors, behind timing of food intake across the 24-h period in the development of obesity, and dietary strategies manipulating meal timing to ameliorate weight gain are also explored.

Recent Findings: Dietary patterns that feature meal timing outside of the regular daytime hours can contribute to circadian disruption as food is metabolised in opposition to internal daily rhythms and can feedback on the timekeeping mechanisms setting these rhythms.

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