Association between hs-CRP/HDL-C ratio and risk of prediabetes or diabetes: a cross-sectional study based on NHANES 2015-2023.

Background: The hs-CRP/HDL-C ratio is a novel marker reflecting inflammation and lipid metabolism disorders, but systematic investigations regarding its association with prediabetes and diabetes are still lacking. This study aimed to explore the association between the hs-CRP/HDL-C ratio and the presence of prediabetes and diabetes, thereby providing a theoretical basis for identifying individuals with dysglycemia at an earlier stage.

Methods: A total of 18,472 eligible adult participants were included based on NHANES data from 2015 to 2023.

PpMATE49, a multidrug and toxic compound extrusion transporter, confers manganese toxicity tolerance in peach (Prunus persica).

Multidrug and toxic compound extrusion (MATE) transporters play critical roles in plant stress responses, including heavy metal detoxification. Although manganese (Mn) toxicity severely limits crop productivity worldwide, the involvement of MATE transporters in Mn tolerance remains poorly understood, especially in perennial fruit crops. In this study, we identified 65 MATE genes in Prunus persica genome, phylogenetically classified into four distinct clades.

The incidence, clinical characteristics, and outcome of polytrauma patients with the combination of pulmonary contusion, flail chest and upper thoracic spinal injury.

Background: Chest trauma was the third most common cause of death in polytrauma patients, accounting for 25% of all deaths from traumatic injury. Chest trauma involves in injury to the bony thorax, intrathoracic organs and thoracic medulla. This study aimed to investigate the incidence, clinical characteristics, and outcome of polytrauma patients with pulmonary contusion, flail chest and upper thoracic spinal injury.

[Features of lung dysfunction in children with Mycoplasma pneumoniae pneumonia with different chest imaging findings].

Objective: To explore the features of pulmonary dysfunction in children with Mycoplasma pneumoniae pneumonia (MPP) with different chest imaging findings.

Methods: The clinical data from 215 children with MPP were reviewed. These patients were grouped based on chest image findings (bronchopneumonia, n=125; lobar pneumonia, n=69; interstitial pneumonia, n=21).

Female sex hormones are associated with the reduction of serum sodium and hypertension complications in patients with aldosterone-producing adenoma.

This study was conducted to evaluate gender-related differences in clinical characteristics and vascular complications in patients with aldosterone-producing adenomas (APA). Clinical characteristics, biochemical markers and incidence of vascular complications were compared by gender in 187 consecutive patients with APA confirmed by pathological diagnosis. Patients were separated into two groups based on ages either older or younger than 49 years, the average age of menopause among Chinese women (<49 y and ≥49 y).

[Epidemiologic characteristics of hand-foot-mouth disease in Guiyang between 2008 and 2010].

Objective: To study the epidemiologic characteristics of hand-foot-mouth disease (HFMD) in Guiyang between 2008 and 2010.

Methods: The epidemiologic characteristics of HFMD were analyzed by descriptive statistical methods based on the data from the China Information System for Disease Control and Prevention.

Results: A total of 27383 cases of HFMD were recorded in Guiyang between 2008 and 2010.

Overexpression of Zip-2 mRNA in the leukocytes of asthmatic infants.

The increase in prevalence of asthma is strongly dependent on environmental factors, including foods. Significant decreases in the intake of dietary zinc may be an important contributing factor to the increasing incidence of asthma. As zinc can not passively diffuse across cell membranes, specific zinc transporters are required for zinc influx and efflux.