Magnetic nanoparticle-decorated metal organic frameworks for chemiluminescence detection of glutathione.

A chemiluminescence (CL) method for determination of glutathione (GSH) was developed with magnetic nanoparticle-decorated metal organic frameworks (FeO NPs@Cu-TATB). The composite material was synthesized via a hydrothermal method and glutathione (GSH) can be detected by both visual and chemiluminescence (CL) methods. The synthesized FeO NPs@Cu-TATB exhibited excellent catalytic activity in the luminol-HO CL system.

Characteristics of endoplasmic reticulum stress in colorectal cancer for predicting prognosis and developing treatment options.

Background: An increasing body of evidence supports an essential role for endoplasmic reticulum stress (ERS) in colorectal cancer (CRC). In this study, we developed an ERS-related genes (ERSRGs) model to aid in the prognostic evaluation and treatment of CRC patients.

Methods: The training set and validation set data were extracted from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO), respectively.

MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.

MicroRNAs (miRNAs) participate in the formation of multiple diseases, including gastric cancer (GC), through modulating specific targets. Here, we explored the functions and regulatory mechanisms of miR-205-5p in GC. MiR-205-5p levels were detected in GC cells through qRT-PCR.

Stable acyclic aliphatic solid enols: synthesis, characterization, X-ray structure analysis and calculations.

A synthetic approach to stable enols was introduced and series of acyclic aliphatic solid enols were obtained and characterized. Relationship between the structure and the stability of these enols was discussed. Gaussian 09 calculations had been carried out to rationalize the stability of the enols.