BuZhong YiQi Formula Alleviates Diabetes-Caused Hyposalivation by Activating Salivary Secretion Pathway in the Parotid and Submandibular Glands of Rats.

: BuZhong Yiqi Formula (BZYQF) has significant ameliorative effects on type 2 diabetes mellitus (T2DM). However, its efficacy in alleviating the hyposalivation caused by T2DM needs to be confirmed, and its mechanism is unclear. : Network pharmacology and molecular docking were combined to analyze the molecular mechanism by which BZYQF alleviates T2DM-caused hyposalivation.

Extrarenal renal cell carcinoma in the adrenal region: a case report.

This case report describes a rare instance of extrarenal clear cell renal cell carcinoma (ccRCC) in a 48-year-old woman who presented with a loss of consciousness. Abdominal CT revealed a 24 × 31 mm mass in the left adrenal region, with no kidney involvement. The mass was surgically excised, and histopathological examination confirmed the diagnosis of ccRCC.

Genome-Wide Identification of the bHLH Gene Family in and Its Expression Analysis in Different Floral Tissues.

Background: The bHLH genes play a crucial role in plant growth, development, and stress responses. However, there is currently limited research on bHLH genes in the important horticultural plant Franch.

Methods: In this study, we conducted a comprehensive genome-wide identification and in-depth analysis of the bHLH gene family in using bioinformatics approaches.

Computer-assisted three-dimensional individualized extreme liver resection for hepatoblastoma in proximity to the major liver vasculature.

Background: The management of hepatoblastoma (HB) becomes challenging when the tumor remains in close proximity to the major liver vasculature (PMV) even after a full course of neoadjuvant chemotherapy (NAC). In such cases, extreme liver resection can be considered a potential option.

Aim: To explore whether computer-assisted three-dimensional individualized extreme liver resection is safe and feasible for children with HB who still have PMV after a full course of NAC.

LINC00240/miR-155 axis regulates function of trophoblasts and M2 macrophage polarization via modulating oxidative stress-induced pyroptosis in preeclampsia.

Background: This study aimed to investigate the effects of LINC00240/miR-155/Nrf2 axis on trophoblast function and macrophage polarization in the pathogenesis of preeclampsia.

Methods: Bindings between LINC00240, miR-155 and Nrf2 were validated by dual luciferase reporter assay or RNA-immunoprecipitation. Cell proliferation, migration, invasion, and pyroptosis were detected by CCK-8, clone formation, wound healing, Transwell system, and flow cytometry, respectively.

Photo-excitation production of medically interesting isomers using intense γ-ray source.

Photon-induced nuclear excitation (i.e. photo-excitation) can be used for production of nuclear isomers, which have potential applications in astrophysics, energy storage, medical diagnosis and treatment.

LncRNA MALAT1 regulates trophoblast cells migration and invasion via miR-206/IGF-1 axis.

Preeclampsia (PE) is a pregnancy-specific syndrome that substantially leads to maternal and fetal mortality. Multiple factors contribute to the disease, but the exact pathogenesis still remains elusive. Here we explored the roles of lncRNA MALAT1 and miR-206 in PE.

Three-Dimensional Reduced Graphene Hydrogels Using Various Carbohydrates for High Performance Supercapacitors.

In present work, three-dimensional (3D) reduced graphene hydrogels (RGHs) are prepared through an efficient and facile strategy by employing three types of carbohydrates (glucose, fructose and sucrose) as reducing agents in aqueous solution of graphene oxide (GO) with ammonia. The formation of RGHs could be confirmed by X-ray powder diffraction (XRD), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FT-IR). The structures and porosity were characterized by field emission scanning electron microscopy (FESEM), high resolution transmission electron microscopy (HRTEM) and N2 sorption experiments.

Liver Fibrosis Can Be Induced by High Salt Intake through Excess Reactive Oxygen Species (ROS) Production.

High salt intake has been known to cause hypertension and other side effects. However, it is still unclear whether it also affects fibrosis in the mature or developing liver. This study demonstrates that high salt exposure in mice (4% NaCl in drinking water) and chick embryo (calculated final osmolality of the egg was 300 mosm/L) could lead to derangement of the hepatic cords and liver fibrosis using H&E, PAS, Masson, and Sirius red staining.

High salt intake negatively impacts ovarian follicle development.

Many human disorders induce high salinity in tissues and organs, interfering with their normal physiological functions. Using a mouse model, we demonstrated that high salt intake caused infertility. Specifically, we established that high salinity dramatically affects ovarian follicle development and the extent of follicular atresia.

Selective recognition of sulfate anions in a 95% ethanol solvent with a simple neutral salicylaldehyde dansyl hydrazine Schiff base tuned by Brønsted-Lowry acid-base reaction.

A new Schiff base compound, 5-(dimethylamino)-N'-(2-hydroxybenzylidene)naphthalene-1-sulfonohydrazide (R), has been synthesized, characterized, and employed as a selective fluorescence receptor for the recognition of sulfate anions. UV-vis absorption, fluorescence emission, (1)H NMR spectra and DFT calculation studies on the system have been carried out to determine the nature of the interactions between R and anions. The results reveal that the deprotonation of the phenol without the need of a strong base leads to the formation of a hydrogen-bonding complex with a -SO2-NH- group, which is responsible for the spectra changes.

The effect of 2n gametes on sex ratios in Actinidia.

Sex can sometimes lead to complications. In some crops, 2n gametes have been exploited by plant breeders to transfer genetic variation between taxa of different ploidy levels. However, their role and use in dioecious genera have received relatively little attention.

Cohort Profile: the China-Anhui Birth Cohort Study.

The China-Anhui Birth Cohort Study (C-ABCS) was set up to examine the delayed, cumulative and interactive effects of maternal environmental exposures on birth outcomes and children's development. The C-ABCS recruited pregnant women from six major cities of Anhui province, China, between November 2008 and October 2010. A range of data (including demographic, obstetric, occupational, nutritional and psychosocial factors) were collected by both interviews and laboratory tests.

Cross-coupling reactions of two different activated alkenes through tetrabutylammonium fluoride (TBAF) promoted deprotonation/activation strategy: a regioselective construction of quaternary carbon centers.

A novel TBAF-promoted intermolecular crossed-conjugate addition has been developed. For a range of cyclic β-halo-α,β-unsaturated carbonyl compounds, the vinylogous enolates generated by deprotonation at the γ-position preferentially reacted with Michael acceptors at the α-position to deliver cross-coupling products in good yields.

Natural hybridization between Rhododendron delavayi and R. cyanocarpum (Ericaceae), from morphological, molecular and reproductive evidence.

The natural hybridization that occurs between two sympatric species of Rhododendron subgenus Hymenanthes in Yunnan, China, was investigated. In field observations, it was noted that the putative hybrids between R. delavayi Franch.

[Effects of sludge retention time (SRT) on the characteristics of membrane bioreactor (MBR)].

The effects of sludge retention time (SRT) on extracellular polymeric substances (EPS) content, the characteristics of sludge, the size distribution of sludge particles and the membrane resistance of filtration in the membrane bioreactor were studied. The results indicate that the EPS content is about 90 mg/g in the mixed liquor and 0.8 g/m2 on the membrane surface at 30 d of SRT.

[Current situation and control strategy of nosocomial infection in intensive care unit].

Intensive care unit (ICU) is a place with high risk of nosocomial infections. Effective control of nosocomial infections in ICU brings both social and economic benefits. This article summarizes ten main points in the control strategy of ICU infections.

[Economic loss of nosocomial infections in patients with cerebral hemorrhage or cerebral infarction].

Objective: To evaluate the economic loss of nosocomial infections (NI) in patients with cerebral hemorrhage or cerebral infarction.

Methods: We used case-control method to compare the medical expenses between 46 pairs of cerebral hemorrhage or cerebral infarction patients with or without NI.

Results: The median hospital stay, total treatment expense, medications expense, examination expense, and treatment expense of NI were significantly higher in the NI group than in non-NI group (all P < 0.

[Spatial variability and the relationships of soil mineral N and topographic factors in a small watershed].

Objective of this study was to understand the spatial pattern of soil properties and topographic factors and their relationships in a small watershed. We used classical statistical coupling with geo-statistical theory to characterize and compare the spatial variability of soil mineral N and topographic factors in the wind-water erosion crisscross region on the Loess Plateau. The results show that: 1) The nitrate's variable extent is strong while other properties are moderate variability, and the impacts of soil types, land uses on variable extent are significant.

Natural hybridization origin of Rhododendron agastum (Ericaceae) in Yunnan, China: inferred from morphological and molecular evidence.

The natural hybridization that occurs between two sympatric species of Rhododendron subgenus Hymenanthes in Yunnan, China, was investigated. The assumed parents, Rhododendron delavayi Franch. and R.

[Role of cytokeratin expression in differential diagnosis of intraductal proliferative lesions of breast].

Objective: To evaluate the expression of cytokeratins in intraductal proliferative lesions of breast, including usual ductal hyperplasia (UDH), atypical ductal hyperplasia (ADH), ductal carcinoma-in-situ (DCIS) and its role in differential diagnosis.

Methods: Ninety two cases of paraffin-embedded lesional breast tissue, 30 cases of frozen samples, cell cultures of hyperplastic ductal cells and 2 invasive ductal carcinoma cell lines (T47D and MCF-7) were used for this study. Immunohistochemistry was performed using EnVision method for 34betaE12, CK8 and CK14.

[Gene diagnosis of facioscapulohumeral muscular dystrophy].

Objective: To observe the characteristics of changes of p13E-11 labelled 4q35 EcoRI fragments and to make a gene diagnosis of facioscapulohumeral muscular dystrophy(FSHD).

Methods: Genomic DNA was extracted and was digested by EcoR I /Bln I. After pulsed field gel electrophoresis, it was hybridized with probe p13E-11 by Southern blot.