In situ observation of oxygen ion dynamics in topological phase change memristors through self-assembled interface design.

Resistive switching memory represents a potentially transformative advancement in next-generation nonvolatile memory and neuromorphic technologies. Recently, vertically aligned nanocomposites (VANs) have been proposed to optimize the memristive performance of single-phase memories. However, the microscopic mechanism of dynamic resistive switching in these VAN architectures is still elusive.

A Simple Optical Convolution Strategy Based on Versatile Adjustable Optical Convolution Kernel for All-Optical Convolution Computing.

Convolutional neural network (CNN) is currently one of the most important artificial neural networks. However, traditional CNN hardware architectures suffer from significant increases in energy consumption and processing time as the demand for artificial intelligence tasks grows. Here, a novel optical convolution computing strategy is proposed that leverages a continuously adjustable photoluminescent device (CA-PLD) as the optical convolution kernel, enabling parallel, all-optical convolution computing and greatly simplifying the traditional convolution process.

Manual manipulation and ex vivo flexible ureteroscopic lithotripsy to salvage deceased donor kidneys with renal stones: a case series.

Background: Nephrolithiasis is generally considered a relative contraindication for kidney donation. This study aimed to evaluate the feasibility and effectiveness of a surgical technique designed to salvage deceased donor kidneys with renal stones. The technique involves manual manipulation of the recovered kidney combined with flexible ureteroscopic lithotripsy (MM-FURSL) to clear the stones prior to transplantation.

Single-Center Retrospective Analysis of Prophylaxis and Treatment of Pneumocystis carinii Pneumonia in Patients with Renal Dysfunction After Renal Transplantation.

BACKGROUND Pneumocystis carinii is an opportunistic pathogen that can cause severe lung infections after renal transplantation. Trimethoprim-sulfamethoxazole (TMP-SMX) has been recognized as a first-line treatment for chemoprophylaxis of Pneumocystis carinii pneumonia (PCP). This study aimed to establish a personalized chemoprophylaxis prescription specifically for those recipients with renal insufficiency.

MicroRNA-200c is involved in proliferation of gastric cancer by directly repressing p27.

P27, also known as Cyclin-dependent kinase inhibitor 1B, is an important check-point protein in the cell cycle. It has been identified that although as a tumor suppressor, P27 is expressed in different cancer cell types, which shows the therapeutic potential in tumor genesis. In this study, we examined the upstream regulatory mechanism of P27 at the microRNA (miRNA) level in gastric carcinogenesis.

MiR-320a inhibits gastric carcinoma by targeting activity in the FoxM1-P27KIP1 axis.

MicroRNAs (miRNAs) regulate tumorigenesis by inhibiting gene expression. In this study, we showed that miR-320a expression is decreased in human gastric cancer tissues and correlates inversely with expression of FoxM1, a key cell cycle regulator involved in gastric carcinoma. By contrast, the expression of P27KIP1, a downstream effector of FoxM1, correlates positively with miR-320a levels.