Publications by authors named "Jiancheng An"
The spectraplakin family protein GAS2 was originally identified as a growth arrest-specific protein, and recent studies have revealed its involvement in multiple cellular processes. Its dual interaction with actin filaments and microtubules highlights its essential role in cytoskeletal organization, such as cell division, apoptosis, and possibly tumorigenesis. However, the structural basis of cytoskeletal dynamics regulation by GAS2 remains unclear.
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- The paper addresses the issue of misdetection and missed detection in breast mass detection using existing target detection models.
- It introduces an improved model called D-Mask R-CNN, which modifies the structure of Feature Pyramid Networks (FPN) and the Region Proposal Network (RPN) to enhance detection accuracy.
- Testing on the CBIS-DDSM dataset showed that the improved model achieved a mean Average Precision (mAP) of 0.66, outperforming the original Mask R-CNN by 0.05.
The eubacterial β sliding clamp (DnaN) plays a crucial role in DNA metabolism through direct interactions with DNA, polymerases, and a variety of protein factors. A canonical protein-DnaN interaction has been identified in Escherichia coli and some other species, during which protein partners are tethered into the conserved canonical hydrophobic crevice of DnaN via the consensus β-binding motif. Caulobacter crescentus is an excellent research model for use in the investigation of DNA replication and cell-cycle regulation due to its unique asymmetric cell division pattern with restricted replication initiation; however, little is known about the specific features of C.
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