Ferroptosis-related lncRNAs as prognostic biomarkers in renal cell carcinoma: a systematic review and meta-analysis.

Background: Abundant evidences have indicated that long non-coding RNAs (lncRNAs) can be used to evaluate the prognosis of patients with renal cell carcinoma (RCC), and the purpose of this study was to evaluate the association between ferroptosis-related lncRNAs (FRLs) and the prognosis of patients with RCC by means of a meta-analysis.

Materials And Methods: All studies assessing the prognosis of patients with FRLs and RCC were collected up to 31 October 2024 by searching databases such as PubMed, Web of Science, Embase, Scopus and Cochrane Library. Pooled analyses were performed on the collected data, including metrics such as gender, age, risk score, tumor stage, and tumor grade.

A universal strategy toward two-component organic-inorganic metal halide luminescent glasses and glass-crystal composites.

The development of melt-quenched organic-inorganic metal halide (OIMH) glasses is hampered by the scarcity of suitable organic molten salts and low luminescence efficiency. Herein, we developed a series of two-component OIMH amorphous glasses consisting of (TPG)MnBr (TPG, triphenylguanidium) and AMnBr (A, organic molten cation), named α(ATPG). The high glass-formation ability (GFA) in (TPG)MnBr provides a platform to modulate the crystallization of another molten AMnBr by homogeneous melting.

Branched Alkyl Chains Tunable Organic-Inorganic Hybrid Manganese Halides for Anti-counterfeiting, White Light-emitting Diode and X-ray Imaging Applications.

Manganese-based organic-inorganic metal halides (Mn-based OIMHs) scintillators have aroused a research upsurge due to their outstanding photoluminescence performance, low toxicity, and tunable structures. Herein, we demonstrate a molecular engineering strategy that synergistically enhances luminescence efficiency and radiation sensitivity by systematic elongation of branched alkyl chains in phosphonium-based cations. The (4-DEATBP)MnBr (4-DEATBP = (4-(diethylamino)butyl)triphenylphosphonium) crystal exhibits remarkable thermochromic luminescence properties and anti-thermal quenching effect, highlighting the application potential in high-temperature anti-counterfeiting and information encryption.

An anti-thermal-quenching organic-inorganic hybrid manganese-based single-crystal scintillator for high-temperature X-ray imaging.

High-temperature X-ray detection holds promising potential in practical applications in the development of industry. Organic-inorganic manganese-based halide (OIMH) scintillators have undergone a research upsurge due to their high X-ray attenuation ability, low preparation cost, outstanding photoluminescence performance, and flexible structures. However, the thermal quenching effects of OIMH materials limit their applications at high temperatures.

Organic-Inorganic Hybrid Rare Earth Halide Glasses for Tunable Multicolor X-ray Scintillation.

Rare earth-based all-inorganic glass-ceramics have played an important role in the field of optoelectronics. However, the research of organo-inorganic hybrid rare earth halide glass that can be produced at low temperatures is still in the blank stage. In this paper, we report for the first time novel amorphous organic-inorganic hybrid rare earth-based halide luminescent glasses, BzmimLnCl (Bzmim = 1-benzyl-3-methylimidazolium; Ln = Tb, Eu), and realize tunable multicolor photoluminescence emission.

Anion-π interaction guided switchable TADF and low-temperature phosphorescence in phosphonium salts for multiplexed anti-counterfeiting.

Anion-π interactions have gained continuous attention in diverse organic aggregates, as they can effectively alter emission behavior. Herein, the anion-π interaction is introduced to phosphonium salts, which exhibit tunable thermally activated delayed fluorescence and phosphorescence emission. Intriguingly, the emission spectra evolve from deep-blue to yellow emission by regulation of the anion-π interaction strength through varying the anions, such as BF , CFSO , PF , and NO, accompanied by adjustable luminescent decay times from milliseconds to several seconds.

Crystallization of CsPbBr Nanocrystals within a Melt-Quenched Glassy Coordination Polymer.

Lead halide perovskite nanocrystal materials such as CsPbX (X = Cl, Br, and I) have triggered an intense research upsurge due to their excellent scintillation performance. Herein, an crystallization strategy is developed to grow CsPbBr nanocrystals (NCs) within a low-melting-point (280 °C) coordination polymer (CP) glass. The viscosity of coordination glass is reduced through a low-temperature (e.

Bisphosphonium cation based metal halide glass scintillators with tunable melting points.

Organic-inorganic metal halide (OIMH) glass offers the advantages of large-scale production, high transparency, and minimal light scattering. However, undesired crystallization in OIMH glass can occur, leading to deteriorated transparency. Herein, a series of bisphosphonium organic cations were designed to construct Mn-based metal halide crystals with a photoluminescence quantum yield (PLQY) near unity, alongside the development of highly thermally stable OIMH glasses.

Large-Area Laminar TEAMnI Single-Crystal Scintillator for X-ray Imaging with Impressive High Resolution.

Current X-ray imaging scintillators are dominated by inorganic scintillators grown through a high-temperature process. Exploring new types of scintillators with mild growth conditions, high light yields, and eco-friendly chemical compositions is essential and challenging. Herein, the zero-dimensional large-area laminar organic-inorganic hybrid metal halide TEAMnI (TEA = tetraethylammonium) single crystal with dimensions of 50 mm × 60 mm × 0.

Multidentate Chelation Heals Structural Imperfections for Minimized Recombination Loss in Lead-Free Perovskite Solar Cells.

Tin-based perovskite solar cells (Sn-PSCs) have emerged as promising environmentally viable photovoltaic technologies, but still suffer from severe non-radiative recombination loss due to the presence of abundant deep-level defects in the perovskite film and under-optimized carrier dynamics throughout the device. Herein, we healed the structural imperfections of Sn perovskites in an "inside-out" manner by incorporating a new class of biocompatible chelating agent with multidentate claws, namely, 2-Guanidinoacetic acid (GAA), which passivated a variety of deep-level Sn-related and I-related defects, cooperatively reinforced the passivation efficacy, released the lattice strain, improved the structural toughness, and promoted the carrier transport of Sn perovskites. Encouragingly, an efficiency of 13.

Zero-Dimensional Zn-Based Halides with Ultra-Long Room-Temperature Phosphorescence for Time-Resolved Anti-Counterfeiting.

Though fluorescence-tag-based anti-counterfeiting technology has distinguished itself with cost-effective features and huge information loading capacity, the clonable decryption process of spatial-resolved anti-counterfeiting cannot meet the requirements for high-security-level anti-counterfeiting. Herein, we demonstrate a spatial-time-dual-resolved anti-counterfeiting system based on new organic-inorganic hybrid halides BAPPZn (Cl Br ) (BAPP=1,4-bis(3-ammoniopropyl)piperazinium, y=0-1) with ultra-long room-temperature phosphorescence (RTP). Remarkably, the afterglow lifetime can be facilely tuned by regulating the halide-induced heavy-atom effect and can be identified by the naked eyes or with the help of a simple machine vision system.

Water-Molecule-Induced Emission Transformation of Zero-Dimension Antimony-Based Metal Halide.

Low-dimensional organic-inorganic metal halides have recently emerged as a class of promising luminescent materials. However, the intrinsic toxicity of lead would strongly hamper future application. Herein, we synthesized a new type of lead-free zero-dimensional (0D) antimony-based organic-inorganic metal halide single crystals, (PPZ)SbCl·5HO (PPZ = 1-phenylpiperazine), which features a broadband emission at 720 nm.

Indium-antimony-halide single crystals for high-efficiency white-light emission and anti-counterfeiting.

Although single-source white emissive perovskite has emerged as a class of encouraging light-emitting material, the synthesis of lead-free halide perovskite materials with high luminous efficiency is still challenging. Here, we report a series of zero-dimensional indium-antimony (In/Sb) alloyed halide single crystals, BAPPIn Sb Cl (BAPP = CHN, = 0 to 1), with tunable emission. In BAPPInSbCl, bright yellow emission with near 100% photoluminescence quantum yield (PLQY) is yielded when it was excited at 320 nm, which turns into bright white-light emission with a PLQY of 44.

Superlubricity between a silicon tip and graphite enabled by the nanolithography-assisted nanoflakes tribo-transfer.

Superlubricity between a cone-shaped (sharp) silicon tip and graphite remains a challenge in the nanotribology field. In this paper, an efficient method of achieving superlubricity between a cone-shaped silicon tip and graphite was proposed. Graphite nanoflakes were transferred onto the silicon tip by repeatedly rubbing against the scratches produced by nanolithography on a graphite surface.

Structural Health Monitoring System Based on FBG Sensing Technique for Chinese Ancient Timber Buildings.

Due to the long-term service, Chinese ancient timber buildings show varying degrees of wear. Thus, structural health monitoring (SHM) for these cultural and historical treasures is desperately needed to evaluate the service status. Although there are some FBG sensing-based SHM systems, they are not suitable for Chinese ancient timber buildings due to the differences in architectural types, structural loads, materials, and environment.

Stepwise dual pH and redox-responsive cross-linked polypeptide nanoparticles for enhanced cellular uptake and effective cancer therapy.

The systemic toxicity, reduced cellular internalization, and uncontrollable intracellular drug release of smart nanoparticles (NPs) still need to be overcome for effective cancer therapy. Herein, a series of stepwise dual pH and redox responsive cross-linked polypeptides based on poly(l-lysine-co-N,N-bis(acryloyl)cystamine-co-γ-glutamic acid) (PLBG), were prepared for enhanced cellular uptake and effective cancer therapy. The prepared cross-linked PLBG nanoparticles (PLBG-NPs) exhibit negatively charged surfaces under physiological conditions, and the surface charge of the PLBG-NPs was observed to switch from negative to positive in a slightly acidic tumor extracellular environment at a pH level of ∼6.

Electrical friction modulation on MoS using electron beam radiation without electrostatic interactions.

Nanoscale friction under different electronic states and the corresponding friction controlling methods are both scientifically interesting and technologically important. However, friction measurements under electrical modulation are severely hampered by electrostatic forces induced by the charge-trapping effect. Therefore, in this study, we developed a new modulation method free from the charge-trapping effect through electron beam radiation; this method successfully modulated the friction between few-layer MoS and the silicon tip on atomic force microscopy.

Surface design and preparation of multi-functional magnetic nanoparticles for cancer cell targeting, therapy, and imaging.

Recently, theranostic candidates based on superparamagnetic iron oxide nanoparticles (SPIONs) providing the combination of therapy and diagnosis have become one of the most promising system in cancer research. However, poor stability, premature drug release, lack of specific tumor cell targeting, and complicated multi-step synthesis processes still hinder them for potential clinical applications. In this research, the multi-functional magnetic nanoparticles (MNPs-DOX) were prepared a simple assembly process for targeted delivery of doxorubicin (DOX) and enhanced magnetic resonance (MR) imaging detection.

Reduction/temperature/pH multi-stimuli responsive core cross-linked polypeptide hybrid micelles for triggered and intracellular drug release.

The high toxicity, poor stability, premature drug release, and lack of intracellular stimuli responsibility of current polymeric micelles still hinder them for potential clinical applications. To address these challenges, a novel type of multi-stimuli responsive, core cross-linked polypeptide hybrid micelles (CCMs) was developed for triggered anticancer drug delivery in tumor microenvironment. The CCMs was prepared via free radical copolymerization by using N,N'-methylene-bis-acylamide (BACy) as the cross-linking agent, 2,2-azobisisobutyronitrile (AIBN) as the initiator, where poly (γ-benzyl-L-glutamate) (PBLG) and N-isopropylacrylamide (NIPPAM) as comonomers.

Microstructure Evolution and Flow Stress Model of a 20Mn5 Hollow Steel Ingot during Hot Compression.

20Mn5 steel is widely used in the manufacture of heavy hydro-generator shaft due to its good performance of strength, toughness and wear resistance. However, the hot deformation and recrystallization behaviors of 20Mn5 steel compressed under high temperature were not studied. In this study, the hot compression experiments under temperatures of 850-1200 °C and strain rates of 0.

Hot Deformation Behavior and a Two-Stage Constitutive Model of 20Mn5 Solid Steel Ingot during Hot Compression.

20Mn5 steel is widely used in the manufacture of heavy hydro-generator shaft forging due to its strength, toughness, and wear resistance. However, the hot deformation and recrystallization behaviors of 20Mn5 steel compressed under a high temperature were not studied. For this article, hot compression experiments under temperatures of 850-1200 °C and strain rates of 0.

Thickness dependent friction on few-layer MoS, WS, and WSe.

Nanoscale friction on two-dimensional (2D) materials is closely associated with their mechanical, electronic and photonic properties, which can be modulated through changing thickness. Here, we investigated the thickness dependent friction on few-layer MoS, WS, and WSe using atomic force microscope at ambient condition and found two different behavior. When a sharp tip was used, the regular behavior of decreasing friction with increasing thickness was reproduced.

Assessment of the associations between three VEGF polymorphisms and risk of prostate cancer.

Unlabelled: Vascular endothelial growth factor (VEGF) plays a crucial role in the regulation of angiogenesis and is involved in the development and metastasis of common cancers. There were several case-controls studies published to assess the associations of VEGF polymorphisms with risk of prostate cancer, but the findings were inconsistent. We performed a meta-analysis to provide a comprehensive assessment of the associations of three VEGF polymorphisms with risk of prostate cancer.