Enhancing glaucoma care with smart contact lenses: An overview of recent developments.

Glaucoma is a leading cause of irreversible blindness worldwide, affecting millions of individuals due to its progressive damage to the optic nerve, often caused by elevated intraocular pressure (IOP). Conventional methods of IOP monitoring, such as tonometry, provide sporadic and often inaccurate readings due to fluctuations throughout the day, leaving significant gaps in diagnosis and treatment. This review explores the transformative potential of smart contact lenses equipped with continuous IOP monitoring and therapeutic capabilities.

Colorimetric detection of hydrogen peroxide and cholesterol using FeO-brominated graphene nanocomposite.

FeO-brominated graphene (FeO-GBR) nanocomposites were synthesized via an in situ method using the precursors FeSO.7HO and GBR in different (1:1, 1:2, 2:1, 1:5, 1:10, 1:20, and 5:1) weight ratios at pH 11.5.

Highly selective fluorescence 'turn off' sensing of picric acid and efficient cell labelling by water-soluble luminescent anthracene-bridged poly(N-vinyl pyrrolidone).

A novel, water-soluble, luminescent anthracene-bridged AA-type bi-arm poly(N-vinylpyrrolidone) (ATC-PNVP) was synthesized using a click reaction between alkyne-terminated PNVP and 9,10-bis(azidomethyl)anthracene. The resultant anthracene-bridged PNVP (ATC-PNVP) was characterized using 1H NMR, FTIR, UV-Vis, and fluorescence spectroscopic methods and GPC analysis. ATC-PNVP showed effective fluorescence properties in an aqueous medium.

Surface ozone in the Doon Valley of the Himalayan foothills during spring.

Elevated ozone (O) pollution is observed every spring over the Northern Indian region including the Himalayan foothills, with a maximum typically in the month of May. However, studies investigating influences of photochemistry and dynamics in the valleys of Central Himalaya are limited. Here, in situ surface O observations conducted at Dehradun (77.

Systematic evaluation of the dependence of deoxyribozyme catalysis on random region length.

Functional nucleic acids are DNA and RNA aptamers that bind targets, or they are deoxyribozymes and ribozymes that have catalytic activity. These functional DNA and RNA sequences can be identified from random-sequence pools by in vitro selection, which requires choosing the length of the random region. Shorter random regions allow more complete coverage of sequence space but may not permit the structural complexity necessary for binding or catalysis.