Publications by authors named "Jaffer Hussain"
Natural products in the form of functional foods have become increasingly popular due to their protective effects against life-threatening diseases, low risk of adverse effects, affordability, and accessibility. Plant components such as phytosterol, in particular, have drawn a lot of press recently due to a link between their consumption and a modest incidence of global problems, such as Type 2 Diabetes mellitus (T2DM), cancer, and cardiovascular disease. In the management of diet-related metabolic diseases, such as T2DM and cardiovascular disorders, these plant-based functional foods and nutritional supplements have unquestionably led the market in terms of cost-effectiveness, therapeutic efficacy, and safety.
View Article and Find Full Text PDFDiscontinuation of Transmission Precautions for COVID-19 Patients: Polymerase Chain Reaction Diagnostics, Patient Delays, and Cycle Threshold Values.
Infect Dis Clin Pract (Baltim Md)
September 2021
Article Synopsis
- The study explores the challenges in determining when to safely discontinue transmission-based precautions for hospitalized COVID-19 patients, highlighting the contrasting guidelines from the CDC.
- A review of 196 patients revealed that many faced delays in leaving isolation due to repeated positive PCR tests, resulting in extended hospital stays and significant costs.
- The findings suggest that clinicians should consider additional data, such as cycle threshold (Ct) values from PCR tests, to make better-informed decisions on discontinuing precautions, especially for potentially contagious patients.
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman Disease (MCD). Recent mechanistic advances have discerned the importance of microRNAs in the virus-host relationship. KSHV has two modes of replication: lytic and latent phase.
View Article and Find Full Text PDFEvaluation of the bag-mediated filtration system as a novel tool for poliovirus environmental surveillance: Results from a comparative field study in Pakistan.
PLoS One
January 2019
Article Synopsis
- Poliovirus environmental surveillance (ES) is essential for tracking silent circulation of the virus, especially as clinical cases decline, and this study compares the effectiveness of a new bag-mediated filtration system (BMFS) to the traditional two-phase separation method.
- In a study conducted in Pakistan from February to November 2016 with 117 samples, BMFS showed significantly better detection rates for both vaccine-related and wild poliovirus types compared to the two-phase method.
- The enhanced detection in BMFS is attributed to a larger volume of water being tested (1620 mL vs. 150 mL), establishing it as a more effective technique for monitoring poliovirus in endemic regions.