Publications by authors named "Jae-Kyeong Lee"

Strains Mo2-6T, S9, KG4-3T, and 50Mo3-2, identified as coagulase-negative, Gram-stain-positive, halotolerant, non-motile coccoid bacteria, were isolated from traditional Korean soybean foods. Strains Mo2-6T and S9 were both catalase- and oxidase-negative, whereas KG4-3T and 50Mo3-2 were catalase-positive but oxidase-negative. The optimal growth conditions for Mo2-6T and S9 were 30°C, 2% NaCl, and pH 7.

View Article and Find Full Text PDF

Background: Bacterial co-infection has been associated with adverse outcomes in patients with COVID-19. Streptococcus pneumoniae is a common cause of community-acquired pneumonia and may contribute to poor clinical outcomes when co-detected in COVID-19 patients. This study aimed to investigate the clinical significance of pneumococcal positivity in hospitalized patients with COVID-19.

View Article and Find Full Text PDF

Two Gram-stain-negative, strictly aerobic, non-motile, rod-shaped bacteria, designated D3-12ᵀ and G2-2ᵀ, were isolated from the phycosphere of marine red algae. Both strains exhibited catalase- and oxidase-positive activities. Strain D3-12ᵀ grew optimally at 30°C, pH 7.

View Article and Find Full Text PDF

Conventional electrospun nanofibrous membranes have been widely used for tissue engineering scaffolds because they can mimic extracellular matrix (ECM), which plays a significant role in cell proliferation, adhesion, and differentiation. However, the inadequate mechanical strength and biological functions of electrospun nanofibrous scaffolds limit the range of their practical applications. In this study, we prepared a uniform levan-based core-shell composite (csCAL) nanofibrous membrane using the coaxial electrospinning technique.

View Article and Find Full Text PDF
Article Synopsis
  • * The study identified 1,369 characterized and 16,204 potential β-lactamases from protein databases, confirming nine new β-lactamases with less than 35% identity to known ones, highlighting diversity among 1,163 β-lactamases from eight clusters.
  • * Gut β-lactamase abundance varies by country, with Japan having the highest and Fiji the lowest; higher abundance correlates with β-lactam use and income, and is significantly increased in patients with certain diseases, emphasizing the importance of
View Article and Find Full Text PDF

COVID-19 can lead to pulmonary complications, including organizing pneumonia. Steroids are essential in treating post-COVID-19 organizing pneumonia. However, research on the clinical benefits of initiating steroid treatment early for this condition is limited.

View Article and Find Full Text PDF

Background: A pulmonary artery-to-aorta (PA/A) ratio of ≥1 is a reliable indicator of pulmonary hypertension and is associated with an increased risk of acute exacerbation of chronic obstructive pulmonary disease (COPD) and long-term mortality in patients with stable COPD. However, it is unclear whether a PA/A ratio of ≥1 is associated with mortality in patients hospitalized with acute exacerbation of COPD. The purpose of this study was to evaluate the clinical course and mortality of patients with PA/A ratios of ≥1 who were hospitalized with acute exacerbation of COPD.

View Article and Find Full Text PDF
Article Synopsis
  • A new Gram-stain-negative and yellow-pigmented bacterium, strain GPA1, was discovered in a plastic waste landfill in South Korea, characterized as a non-motile short rod that grows well at temperatures of 15-40°C, with an optimum at 30°C, and prefers pH levels of 7.0-8.0.
  • The bacterium contains menaquinone-7 as its sole respiratory quinone and features specific fatty acids and polar lipids, indicating unique biochemical properties.
  • Phylogenetic analysis reveals strain GPA1 as a distinct species within its genus, showing a very high similarity to related strains but notable differences in genetic identity, leading to the proposal of a novel species
View Article and Find Full Text PDF

Few studies have examined the risk factors associated with the type of acute respiratory failure (ARF) in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). This study evaluated the clinical characteristics and prognosis of patients hospitalized for acute exacerbation of COPD based on the type of ARF. The medical charts of hospitalized patients with acute exacerbation of COPD between 2016 and 2021 were retrospectively reviewed.

View Article and Find Full Text PDF

A Gram-stain-negative, facultative aerobic, catalase- and oxidase-positive, non-motile, non-flagellated, and coccus-shaped bacterium, strain J2-16, isolated from a marine green alga, was characterized taxonomically. Strain J2-16 grew at 20-40 °C (optimum, 30 °C), pH 6.0-10.

View Article and Find Full Text PDF

Two Gram-stain-negative, facultatively aerobic, and motile rod bacteria, designated as strains KJ51-3 and 15G1-11, were isolated from marine algae collected in the Republic of Korea. Both strains exhibited catalase- and oxidase-positive activities. Optimum growth conditions for strain KJ51-3 were observed at 30 °C and pH 6.

View Article and Find Full Text PDF

Two Gram-stain-negative, strictly aerobic rods, designated as RMAR6-6 and KMA01, exhibiting catalase- and oxidase-positive activities, were isolated from marine red algae in the Republic of Korea. Cells of strain RMAR6-6 exhibited flagellar motility, while those of strain KMA01 were non-motile. Strain RMAR6-6 exhibited optimal growth at 30-35°C and pH 7.

View Article and Find Full Text PDF

Mitt. (Jungermanniidae, Porellaceae), a bryophyte is widespread in temperate Asia and North America. In Korea, is mainly observed in shaded and dried rocks or tree trunks on mountains.

View Article and Find Full Text PDF

Background: Hyperuricemia is common during tuberculosis (TB) treatment, especially in association with pyrazinamide (PZA). This study investigated the relationship between major adverse cardiovascular events (MACEs) and hyperuricemia during TB treatment.

Methods: We conducted a single-center retrospective cohort study.

View Article and Find Full Text PDF

In this study, we aimed to investigate the feasibility of serum Krebs von den Lungen-6 (KL-6) as a potential biomarker for treatment-related ILD (TR-ILD) in lung cancer. We recruited patients with lung cancer in whom KL-6 was measured to differentiate between pneumonia and ILD (category 1), diagnose and assess the severity of suspicious ILD (category 2), or evaluate baseline levels before cancer treatment (category 3). Among 1,297 patients who underwent KL-6 testing, 422 had lung cancer, and TR-ILD was detected in 195 patients.

View Article and Find Full Text PDF

A Gram-stain-positive alkali-tolerant and strictly aerobic bacterium, designated strain P16, was isolated from a marine red alga, , in the Yellow Sea, Republic of Korea. Cells were motile rods with peritrichous flagella and exhibited catalase and oxidase activities. The optimal growth of strain P16 was observed to occur at 30 °C and pH 8.

View Article and Find Full Text PDF

A Gram-positive, non-motile, and non-spore-forming lactic acid bacterium, designated as BK2, was isolated from kimchi, a Korean traditional fermented vegetable food, and the taxonomic characteristics of strain BK2, along with strain LMG 11983, were analyzed. Both strains optimally grew at 30°C, pH 7.0, and 1.

View Article and Find Full Text PDF

Nontuberculous mycobacteria (NTM) are ubiquitous organisms, but can cause a chronic pulmonary infection in some patients. Therefore, there could be host factors susceptible to this disease. A structural lung disease including damages of lungs caused by previous respiratory infection has been suggested as a host factor.

View Article and Find Full Text PDF

A Gram-stain-negative, yellow-pigmented and facultatively aerobic bacterium, designated strain U1, was isolated from plastic dumped soil sampled in the Republic of Korea. Cell of strain U1 were non-motile rods showing catalase-negative and oxidase-positive activities. Strain U1 was shown to grow at 10-37 °C (optimum, 25-30 °C) and pH 6.

View Article and Find Full Text PDF

Background: Hemocoagulase batroxobin is used to prevent hemostasis or bleeding in surgical and trauma patients; however, the role of batroxobin in patients with hemoptysis is not well understood. We evaluated the risk factors and prognosis of acquired hypofibrinogenemia in hemoptysis patients treated systemically with batroxobin.

Methods: We retrospectively reviewed the medical charts of hospitalized patients who were administered batroxobin for hemoptysis.

View Article and Find Full Text PDF

Objective: In-hospital tuberculosis (TB) transmission remains a concern. Airborne infection isolation (AII) can be discontinued in hospitalized patients with suspected active pulmonary TB when the results of three consecutive sputum acid-fast bacilli (AFB) smears are negative. However, fiberoptic bronchoscopy can be performed in patients who may have difficulty in producing sputum samples.

View Article and Find Full Text PDF

Objective: Pulmonary arteriovenous malformation (PAVM) is a rare pulmonary disease. Although most patients with PAVMs are asymptomatic, cerebral complications associated with PAVMs are often fatal. This study aimed to evaluate the risk factors for cerebral complications in patients with PAVMs.

View Article and Find Full Text PDF

Tracheal tumors are rare diseases. They can cause narrowing of a central airway, a severe respiratory distress, and death. The objective of this case series is to highlight the role of rigid bronchoscopy in diagnosing and treating carina masses which are difficult to remove surgically.

View Article and Find Full Text PDF

Since it is a widely known fact that smoking cessation is beneficial physically and cognitively, efforts should be made to enable smokers to quit smoking through policy. Intensive care smoking cessation camps generally show a high smoking cessation success rate, but research is needed to determine which smokers should be admitted due to costeffectiveness. Although many studies have been conducted to find factors related to smoking cessation success, there is still controversy about the will and success rate of smoking cessation of elderly smokers.

View Article and Find Full Text PDF

Rationale: Nontuberculous mycobacteria (NTM)-associated pleuritis is a very rare disease. Here, we describe 2 cases of life-threatening Mycobacterium intracellulare-associated pleuritis in immunocompetent hosts.

Patient Concerns: A 78-year-old man with sudden onset-onset dyspnea (case 1) and an 80-year-old man with cough, sputum and fever (case 2) presented to our emergency room.

View Article and Find Full Text PDF