Publications by authors named "Inam Danish Khan"

Purpose: This study aims to renew the management of viral epidemic conjunctivitis by introducing a one-time, low-concentration ocular surface povidone-iodine (LOS-pI) wash.

Methods: Among the 3,002 patients screened, 1,328 with acute conjunctivitis were categorized into two groups. Group A (664 patients) underwent a 1% betadine wash in addition to the standard treatment protocol (Eye Lubricant + Moxifloxacin 0.

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Climate change and shifts in land use/land cover (LULC) are critical factors affecting the environmental, societal, and health landscapes, notably influencing the spread of infectious diseases. This study delves into the intricate relationships between climate change, LULC alterations, and the prevalence of vector-borne and waterborne diseases in Coimbatore district, Tamil Nadu, India, between 1985 and 2015. The research utilised Landsat-4, Landsat-5, and Landsat-8 data to generate LULC maps, applying the maximum likelihood algorithm to highlight significant transitions over the years.

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Cytomegalovirus (CMV) colitis occurs commonly in immunocompromised patients with high mortality. CMV infection has also been reported in immunocompetent individuals and it has a varied clinical presentation. When HIV-infected patients are started on antiretroviral therapy (ART) there is a reconstitution of the immune system which results in the paradoxical worsening of existing conditions or development of new disease conditions known as immune reconstitution inflammatory syndrome (IRIS).

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Article Synopsis
  • Device-associated infections (DAIs) like VAP, CLABSI, and CAUTI significantly threaten patient safety and can be prevented through effective surveillance and infection control methods.
  • A study involving over 2000 ICU patients revealed a DAI incidence rate of 7.40 per 1000 device days, with multiresistant pathogens being the most common infections identified.
  • The overall mortality rate in the ICU was 24.85%, with a lower rate of 9.79% for patients who developed DAIs, highlighting the importance of proactive infection prevention measures.
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Article Synopsis
  • Enteric fever, caused by multidrug-resistant Salmonella, is a growing public health issue in developing countries, particularly in Pakistan and India, prompting the use of WHO reserve antibiotics like azithromycin.
  • A study of 782 blood culture isolates from a large North Indian hospital revealed significant resistance rates of S. Typhi and S. Paratyphi, with 6.1% resistance to co-trimoxazole and 2.73% multidrug resistance in S. Typhi.
  • The findings emphasize the need for continuous monitoring of antibiotic resistance and implementation of water, sanitation, hygiene, and vaccination measures to control the spread of enteric fever.
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Objective: Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance that is diagnosed for the first time during pregnancy. This prospective study was undertaken to validate the single-step non-fasting 75 gm Diabetes in Pregnancy Study Group of India (DIPSI) criteria of GDM in Indian patients in comparison with the two-step fasting 100 gm glucose challenge through the Carpenter Coustan criteria (CCC).

Materials And Methods: Two hundred patients underwent comparative testing using the DIPSI criteria and CCC.

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Background: Device-Associated Healthcare-Associated Infections (DA-HAI), including Ventilator-Associated Pneumonia (VAP), Central-Line-Associated Blood Stream Infection (CLABSI), and Catheter-Related Urinary Tract Infection (CAUTI), are considered as principal contributors to healthcare hazard and threat to patient safety as they can cause prolonged hospital stay, sepsis, and mortality in the ICU. The study intends to characterize DA-HAI in a tertiary care multidisciplinary ICU of a teaching hospital in eastern India.

Methods: This prospective outcome-surveillance study was conducted among 2157 ICU patients of a 760-bedded teaching hospital in Eastern India.

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Trichosporonosis is an emerging infection predominantly caused by Trichosporon asahii which is a ubiquitous and exclusively anamorphic yeast. T. asahii urinary tract infection is rare and remains scantily reported.

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Background: One-tenth of all infectious diseases are attributable to emerging organisms. As emerging organisms sporadically affect a relatively small percentage of population they are not studied at large. This study was aimed at studying the characteristics of emerging organisms encountered from various clinical samples in an apex tertiary care multispeciality teaching and research hospital.

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Background: Dengue is an emerging public health problem causing serious morbidity and mortality in tropical developing countries. Early, sensitive and specific diagnosis is paramount for clinical decision making. Currently available diagnostic tests are limited in scope and utility.

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Background: High Altitude Pulmonary Oedema (HAPO) is the most common challenging emergency at Siachen Glacier. This study was aimed at studying various aspects of Extreme Altitude Pulmonary Oedema (>5500 m/18,000 ft) while correlating it with acclimatization and post acclimatization duration of stay in retrospect and response to HAPO Bag nursing prospectively.

Methods: All clinical cases of HAPO on Siachen were included.

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