Changes in physical activity before and after the diagnosis of dyslipidemia and the risk of atrial fibrillation: a population-based study in South Korea.

Objective: While physical activity is known to influence atrial fibrillation risk in the general population, evidence is limited among patients newly diagnosed with dyslipidemia. This study aimed to evaluate the association between changes in physical activity before and after dyslipidemia diagnosis and atrial fibrillation risk.

Methods: Using the Korean National Health Insurance Service database, we identified 441,509 Korean adults newly diagnosed with dyslipidemia between 2011 and 2015, free of atrial fibrillation at baseline and with complete data.

Increased risk of colorectal adenoma and benign colorectal polyp associated with infection: a systematic review and meta-analysis.

Background: Although the association between () infection and the risk of colorectal adenomas (CRAs) is suggested, specific analysis of the histological subtype of CRA is limited. The aim of the study was to conduct a meta-analysis on the risk of histological classifications of CRA as benign colorectal polyp (BCP), CRA, and advanced CRA to investigate the effects of .

Methods: A comprehensive literature searches of the PubMed, Embase, and Cochrane databases through January 2024.

Association of Metabolic Dysfunction-Associated Steatotic Liver Disease With Sudden Sensorineural Hearing Loss Among Older Adults.

Objectives: This study examined the association between metabolic dysfunction-associated steatotic liver disease (MASLD) and the risk of sudden sensorineural hearing loss (SSNHL) in elderly individuals.

Methods: A population-based cohort study using the Korean National Health Insurance Service-Senior cohort included 189,623 individuals aged 65 and older, categorized as non-SLD or MASLD. Cox proportional hazards regression and Fine-Gray subdistribution hazard models were used to evaluate the risk of SSNHL and Ménière's disease, considering all-cause mortality as a competing event.

Combined Effects of Statin Medication Adherence and Fine Particulate Air Pollution on Cardiovascular Disease Among Older Adults.

Background: Emerging research suggests the potential combined effects of statin medication and fine particulate matter exposure on cardiovascular disease (CVD) risk among older adults. These findings underscore the need for further detailed investigations. This cohort study aims to examine the combined effects of adherence to statins and particulate matter with aerodynamic diameter ≤2.

Association between cholecystectomy and chronic kidney disease risk: a nationally retrospective cohort study.

Background: Cholecystectomy, a common surgery, has been associated to various health issues. Some evidence suggests associations between gallbladder removal and elevated risks of metabolic and cardiovascular diseases. However, the potential association between cholecystectomy and chronic kidney disease (CKD) remains understudied.

Association of Physical Activity with Dementia Risk in Cancer Survivors: A Korean Nationwide Cohort Study.

Purpose: This study aimed to investigate the impact of physical activity on dementia risk among cancer survivors in South Korea.

Materials And Methods: This retrospective, population-based cohort study included 344,152 cancer survivors identified from the National Health Insurance Service database in South Korea. The mean follow-up time was 5.

Association between Antibiotic Use and Subsequent Risk of Breast Cancer: A Nationwide Retrospective Cohort Study in South Korea.

Several studies have revealed a possible association between antibiotic use and breast cancer in the Western population of women. However, its association with the Asian population remains unclear. Data utilized in this nationwide population-based retrospective cohort study were obtained from the Korean National Health Insurance Service database.

Combined Effects of Air Pollution and Changes in Physical Activity With Cardiovascular Disease in Patients With Dyslipidemia.

Background: Sedentary behavior elevates cardiovascular disease (CVD) risk in patients with dyslipidemia. Increasing physical activity (PA) is recommended alongside pharmacological therapy to prevent CVD, though benefits across environmental conditions are unclear.

Methods And Results: We analyzed data from 113 918 newly diagnosed patients with dyslipidemia (2009-2012) without prior CVD, sourced from the Korea National Health Insurance Service.

Antibiotic Exposure and Risk of Parkinson Disease in South Korea: A Nationally Representative Retrospective Cohort Study.

Background And Objectives: Recent studies have suggested that antibiotics could be a contributing factor to Parkinson disease (PD), but validation in other population cohorts, such as Asians, is needed. This study examined the association between exposure to antibiotics and PD risk in the Korean population.

Methods: Using the National Health Insurance Service (NHIS) database, this population-level cohort research study from Korea included 298,379 people aged 40 years and older who underwent a national health examination in 2004-2005.

Association between antibiotic use and the risk of rheumatoid arthritis: a retrospective cohort study in South Korea.

Objectives: Certain studies propose that antibiotic use may influence RA incidence, but the clear association between antibiotics and RA remains unclear. Therefore, this study aimed to examine the relationship between antibiotics and RA risk to provide additional epidemiological evidence.

Methods: This population-based retrospective cohort study was conducted with adults aged 40 years or older using the Korean National Health Insurance Service database.

Association between antibiotics use and osteoporotic fracture risk: a nationally representative retrospective cohort study.

Unlabelled: This population-based retrospective cohort study aimed to estimate the association between antibiotic exposure and osteoporotic fracture risk. Long-term antibiotic use was associated with the risk of osteoporotic fracture. An increase in the number of antibiotic classes prescribed may also be associated with an increased osteoporotic fracture risk.

Incidence of hearing loss following COVID-19 among young adults in South Korea: a nationwide cohort study.

Background: The association of COVID-19 with hearing loss (HL) is unclear among young adults and needs to be investigated. This study was conducted to determine the association of COVID-19 with HL and sudden sensorineural hearing loss (SSNHL) in young adults.

Methods: This nationwide population-based cohort study used data from the Korea Disease Control and Prevention Agency-COVID-19-National Health Insurance Service.

Evolutionary changes in metabolic dysfunction-associated steatotic liver disease and risk of hepatocellular carcinoma: A nationwide cohort study.

Background/aims: To determine the association between evolutionary changes in metabolic dysfunction-associated steatotic liver disease (MASLD) status and the risk of hepatocellular carcinoma (HCC) in a nationwide population-based cohort.

Methods: Information on study participants was derived from the Korea National Health Insurance Service database. The study population consisted of 5,080,410 participants who underwent two consecutive biennial health screenings between 2009 and 2012.

Association of balance impairment with risk of incident cardiovascular diseases among older adults.

Background: Rapid decline in balance is a hallmark of aging, elevating the risk of falls and other age-related geriatric illnesses among older adults.

Objective: Our aim was to assess whether impairment in balance function is associated with the risk of incident CVD in older adults.

Design: Retrospective cohort analysis.

Risk of Bell's palsy following SARS-CoV-2 infection: a nationwide cohort study.

Objectives: Despite some evidence of an increased risk of neurologic symptoms following viral vector COVID-19 vaccine administration, it is unclear whether SARS-CoV-2 infection is associated with Bell's palsy (BP), especially over a long enough follow-up period.

Methods: The study population of this nationwide population-based study was derived from the South Korean population, including 11 593 365 and 36 565 099 participants with and without COVID-19, respectively. The Fine and Gray's regression model was utilized to calculate the adjusted subdistribution hazard ratio (aSHR), considering death as a competing risk, to assess the association between SARS-CoV-2 infection and the risk of BP.

Inverse association between changes in systolic and diastolic blood pressure and risk of depression: A nationally representative cohort study.

Background: Depression is one of complex mental disorders with diverse etiological factors but the association between blood pressure (BP) and depression is unknown. We aimed to investigate the association between changes in BP (systolic and diastolic) and incident depression.

Methods: From the National Health Insurance Service-Health Screening Cohort (NHIS-HEALS), 224,192 participants who underwent biennial health screenings from period I (2004-05) and II (2006-07) were included in the study.