Publications by authors named "Hua-Jun Cai"
10-year experience with single-site laparoscopic-assisted Soave operation for Hirschsprung disease.
Minim Invasive Ther Allied Technol
June 2025
Background: The aim of this study was to investigate the clinical outcomes after a transumbilical single-site laparoscopic-assisted Soave operation (TSLSO) for Hirschsprung disease (HD) in children, with a 10-year follow‑up results assessment.
Methods: We retrospectively analyzed the clinical data of 165 children with HD from January 2013 to January 2023. The operation method was a TSLSO.
Article Synopsis
- - Neuroendocrine neoplasms (NENs) are diverse tumors that originate from neuroendocrine cells, with gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) being the most common type.
- - Recent studies show that GEP-NENs are becoming more prevalent and may have a more aggressive nature than previously thought, leading to limited life expectancy for patients.
- - The review highlights the need for improved research on diagnosis and management of GEP-NENs, addressing current limitations in understanding their epidemiology, clinical features, and treatments.
Article Synopsis
- Immunotherapies targeting ligand-receptor interactions (LRIs) are being developed for treating colorectal cancer (CRC), but their impact on the disease's progression and treatment effectiveness remains unclear.
- The study analyzed over 55,000 single-cell RNA sequencing samples and additional data from 1,411 CRC patients to understand LRIs' roles in tumor microenvironment, immunotherapy response, and patient prognosis.
- Findings include identifying CRC subtypes based on LRIs, establishing a prognostic model linked to these interactions, and suggesting potential targets for CRC therapy, improving risk assessments for patients.
Development and validation of a ferroptosis-related lncRNAs prognosis signature in colon cancer.
Bosn J Basic Med Sci
October 2021
Ferroptosis is a form of iron-dependent programmed cell death. Regulation of ferroptosis in tumor cells is a novel treatment modality. The present study aimed to investigate ferroptosis-related long non-coding RNAs (lncRNAs) and construct a prognostic model for colon adenocarcinoma (COAD).
View Article and Find Full Text PDFGold-catalyzed intermolecular hydroamination of allenes with sulfonamides.
Beilstein J Org Chem
June 2013
A co-catalyst of (PPh3)AuCl/AgOTf for the intermolecular hydroamination of allenes with sulfonamides is shown. The reaction proceeded smoothly under mild conditions for differently substituted allenes giving N-allylic sulfonamides in good yields with high regioselectivity and E-selectivity.
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