Am J Ind Med
September 2025
Background: Occupational heat stress recommendations aim to achieve thermal equilibrium and keep core temperature (T) below 38.0°C. We assessed the recommended alert limit curves when: (1) work-rest ratios are adjusted based on wet-bulb globe temperature (WBGT) at a fixed rate of metabolic heat production (H) and (2) H is adjusted based on WBGT at a fixed work-rest ratio.
View Article and Find Full Text PDFBartman, NE, Temple, JL, Hess, HW, Colburn, D, and Hostler, D. Exertional heat strain after an energy drink and caffeine-equivalent beverage in wildland firefighting garments. J Strength Cond Res 39(8): e1026-e1035, 2025-Caffeine is widely consumed for its stimulant properties and potential ergogenic benefits.
View Article and Find Full Text PDFJ Appl Physiol (1985)
March 2025
Violation of the National Institute of Occupational Safety and Health (NIOSH) heat stress recommendations by exceeding the allowable wet bulb globe temperature (WBGT) for a given work intensity and work-rest ratio augments acute kidney injury (AKI) risk. Here, we tested the hypothesis that exceeding the allowable work intensity at a given WBGT and work-rest ratio would also worsen AKI risk. Twelve healthy adults completed two NIOSH recommendation compliant trials and one noncompliant trial consisting of a 4 h (half workday) exposure.
View Article and Find Full Text PDFAppl Physiol Nutr Metab
January 2025
Wildland firefighters can work at high intensity in hot environments for extended periods of time. The resulting heat strain may be modified by the environmental conditions (i.e.
View Article and Find Full Text PDFOccupational heat stress increases acute kidney injury risk. Drinking a soft drink sweetened with high fructose corn syrup further elevates this acute kidney injury risk. However, the impact of sucrose, another fructose-containing sweetener, on acute kidney injury risk remains unexplored.
View Article and Find Full Text PDFAm J Physiol Renal Physiol
August 2024
We tested the hypothesis that compliance with the National Institute for Occupational Safety and Health (NIOSH) heat stress recommendations will prevent reductions in glomerular filtration rate (GFR) across a range of wet-bulb globe temperatures (WBGTs) and work-rest ratios at a fixed work intensity. We also tested the hypothesis that noncompliance would result in a reduction in GFR compared with a work-rest matched compliant trial. Twelve healthy adults completed five trials (four NIOSH compliant and one noncompliant) that consisted of 4 h of exposure to a range of WBGTs.
View Article and Find Full Text PDFJ Strength Cond Res
July 2024
Pryor, JL, Sweet, D, Rosbrook, P, Qiao, J, Hess, HW, and Looney, DP. Resistance training in the heat: Mechanisms of hypertrophy and performance enhancement. J Strength Cond Res 38(7): 1350-1357, 2024-The addition of heat stress to resistance exercise or heated resistance exercise (HRE) is growing in popularity as emerging evidence indicates altered neuromuscular function and an amplification of several mechanistic targets of protein synthesis.
View Article and Find Full Text PDFUndersea Hyperb Med
April 2024
Introduction: Indigenous populations renowned for apneic diving have comparatively large spleen volumes. It has been proposed that a larger spleen translates to heightened apnea-induced splenic contraction and elevations in circulating hemoglobin mass (Hb), which, in theory, improves O carrying and/or CO/pH buffering capacities. However, the relation between resting spleen volume and apnea- induced increases in Hb is unknown.
View Article and Find Full Text PDFAm J Physiol Renal Physiol
May 2024
Men are likely at greater risk for heat-induced acute kidney injury compared with women, possibly due to differences in vascular control. We tested the hypothesis that the renal vasoconstrictor and vasodilator responses will be greater in younger women compared with men during passive heat stress. Twenty-five healthy adults [12 women (early follicular phase) and 13 men] completed two experimental visits, heat stress or normothermic time-control, assigned in a block-randomized crossover design.
View Article and Find Full Text PDFWheelock, CE, Stooks, J, Schwob, J, Hess, HW, Pryor, RR, and Hostler, D. Partial and complete fluid replacement maintains exercise performance in a warm environment following prolonged cold-water immersion. J Strength Cond Res 38(2): 290-296, 2024-Special warfare operators may be exposed to prolonged immersion before beginning a land-based mission.
View Article and Find Full Text PDFUndersea Hyperb Med
January 2024
We tested the hypotheses that self-paced aerobic exercise performance is reduced following four hours of cold-water immersion when breathing air and further reduced when breathing 100% oxygen (O2). Nine healthy adults (four women; age 24 ± 3 years; body fat 17.9 ± 6.
View Article and Find Full Text PDFOccupational heat stress recommendations attenuate AKI risk compared with a work–rest ratio–matched positive control scenario. Heat-induced AKI risk is strongly related to peak core temperature. The peak change in serum creatinine largely paralleled peak changes in urinary [insulin-like growth factor-binding protein 7·tissue inhibitor metalloproteinase 2].
View Article and Find Full Text PDFIntroduction: We tested the hypothesis that a carbohydrate (CHO: 6.5%) or carbohydrate-electrolyte (CHO + E: 6.5% + 50 mmol/L NaCl) drink would better recover plasma volume (PV) and exercise performance compared to water (H2O) after immersion diuresis.
View Article and Find Full Text PDFJ Appl Physiol (1985)
June 2023
Renal ischemia-reperfusion (I/R) injury results in damage to the renal tubules and causes impairments in sodium [Na] reabsorption. Given the inability to conduct mechanistic renal I/R injury studies in vivo in humans, eccrine sweat glands have been proposed as a surrogate model given the anatomical and physiological similarities. We tested the hypothesis that sweat Na concentration is elevated following I/R injury during passive heat stress.
View Article and Find Full Text PDFGovernment entities issue recommendations that aim to maintain core temperature below 38.0°C and prevent dehydration [>2% body mass loss] in unacclimated workers exposed to heat. Hydration recommendations suggest drinking 237 mL of a cool sport drink every 15-20 min.
View Article and Find Full Text PDFAm J Physiol Regul Integr Comp Physiol
November 2022
This study tested the hypotheses that ) spleen volume increases during head-out-of-water immersion (HOWI) and returns to pre-HOWI values postdiuresis, and ) the magnitude of apnea-induced spleen contraction increases when preapnea spleen volume is elevated. Spleen volume was measured before and after a set of five apneas in 12 healthy adults (28 ± 5 yr, 3 females) before, during (at 30 and 150 min), and 20 min after temperate temperature (36 ± 1°C) HOWI. At each time point, spleen length, width, and thickness were measured via ultrasound, and spleen volume was calculated using the Pilström equation.
View Article and Find Full Text PDFAm J Physiol Regul Integr Comp Physiol
September 2022
We tested the hypothesis that, compared with normothermia, the increase in glomerular filtration rate (GFR) after an oral protein load (defined as the GFR reserve) is attenuated during moderate passive heat stress in young healthy adults. Sixteen participants (5 women; 26 ± 2 yr) completed two experimental visits, heat stress or a normothermic time-control, assigned in a block-randomized crossover design. During the heat stress trial, core temperature was increased by 0.
View Article and Find Full Text PDFWet bulb temperatures (T) during extreme heat events are commonly 31°C. Recent predictions indicate that T will approach or exceed 34°C. Epidemiological data indicate that exposure to extreme heat events increases kidney injury risk.
View Article and Find Full Text PDFUndersea Hyperb Med
January 2021
Exposure to a reduction in ambient pressure such as in high-altitude climbing, flying in aircrafts, and decompression from underwater diving results in circulating vascular gas bubbles (i.e., venous gas emboli [VGE]).
View Article and Find Full Text PDFAm J Physiol Regul Integr Comp Physiol
August 2021
Occupational heat exposure is linked to the development of kidney injury and disease in individuals who frequently perform physically demanding work in the heat. For instance, in Central America, an epidemic of chronic kidney disease of nontraditional origin (CKDnt) is occurring among manual laborers, whereas potentially related epidemics have emerged in India and Sri Lanka. There is growing concern that workers in the United States suffer with CKDnt, but reports are limited.
View Article and Find Full Text PDFAm J Physiol Regul Integr Comp Physiol
August 2021
Tonic carotid body (CB) activity is reduced during exposure to cold and hyperoxia. We tested the hypotheses that cold water diving lowers CB chemosensitivity and augments CO retention more than thermoneutral diving. Thirteen subjects [age: 26 ± 4 yr; body mass index (BMI): 26 ± 2 kg/m) completed two 4-h head-out water immersion protocols in a hyperbaric chamber (1.
View Article and Find Full Text PDFUndersea Hyperb Med
June 2021
Exposure to a reduction in ambient pressure such as in high-altitude climbing, flying in aircrafts, and decompression from underwater diving results in circulating vascular gas bubbles (i.e., venous gas emboli [VGE]).
View Article and Find Full Text PDFUndersea Hyperb Med
June 2021
Introduction: Pre-dive altitude exposure may increase respiratory fatigue and subsequently augment exercise ventilation at depth. This study examined pre-dive altitude exposure and the efficacy of resistance respiratory muscle training (RMT) on respiratory fatigue while diving at altitude.
Methods: Ten men (26±5 years; VO2peak: 39.
Aerosp Med Hum Perform
October 2020
Hypoxia-induced hyperventilation is an effect of acute altitude exposure, which may lead to respiratory muscle fatigue and secondary locomotor muscle fatigue. The purpose of this study was to determine if resistive and/or endurance respiratory muscle training (RRMT and ERMT, respectively) vs. placebo respiratory muscle training (PRMT) improve cycling performance at altitude.
View Article and Find Full Text PDFJ Appl Physiol (1985)
August 2020
Hyperoxia reduces the ventilatory response to hypercapnia by suppressing carotid body (CB) activation. This effect may contribute to CO retention during underwater diving due to the high arterial O content associated with hyperbaria. We tested the hypothesis that CB chemosensitivity to hypercapnia and hypoxia is attenuated during hyperbaria.
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