Bioinspired prussian blue nanopesticides with triple-stimuli-responsive gates for ecology-adaptive pest management.

The escalating complexity of pest dynamics, characterized by intensifying seasonal pressures and unpredictable acute outbreaks, necessitates advanced agrochemicals capable of dynamically adapting to ecological rhythms. Inspired by the dual-phase biocontrol strategy of parasitoid wasps (immediate paralysis and sustained suppression), we engineered a Prussian blue (PB)-based nanopesticide (PAPP) with spatiotemporally decoupled release modes. Architecturally, the system integrates pH-responsive PB (alkaline-triggered disintegration) cores with thermosensitive poly(N-isopropylacrylamide) (PNIPAM, heat-induced volumetric transition) nanohydrogel gates, achieving dual-modal pest management: alkaline-triggered burst avermectin (AVM) release (91.

FEN1-assisted LAMP for specific and multiplex detection of pathogens associated with community-acquired pneumonia.

Lower respiratory tract infections (LRITs), including community-acquired pneumonia (CAP), are the fifth leading cause of death worldwide over the last ten years, posing a serious threat to global healthcare. Conventional laboratory assays for detecting pathogens are hindered by complicated procedures, a long turnaround time and a lack of multiplex detection capabilities. In this study, a flap-endonuclease 1 (FEN1)-assisted loop-mediated isothermal amplification (LAMP) method was designed, and an assay based on this method was developed to identify three leading pathogens for CAP, namely, , and .

Green Carbon Dots/CaCO/Abamectin Colloidal Pesticide Formulation for Safer and More Effective Pest Management.

An ideal green leaf-deposited pesticide formulation should offer advantages such as good water dispersibility, strong foliar affinity, sustained or controlled release of active ingredients, photostability and rain-fastness, minimal nontarget toxicity, use of nontoxic organic solvents, and degradable adjuvants. In line with this objective, we present green preparation of a colloidal pesticide formulation using optimized lysine-derived carbon dots (LysCDs)-modified CaCO (LysCDs/CaCO) particles as the carrier and abamectin (Abm) as the active ingredient. The loading capacity of abamectin in this colloidal pesticide (LysCDs/CaCO/Abm) is 1.

Spherical Assembly of Halloysite Clay Nanotubes as a General Reservoir of Hydrophobic Pesticides for pH-Responsive Management of Pests and Weeds.

The development of smart systems for pesticidal delivery presents a significant advancement in enhancing the utilization efficiency of pesticides and mitigating environmental risks. Here an acid-responsive pesticidal delivery system using microspheres formed by the self-assembly of halloysite clay nanotubes (HNTs) is proposed. Insecticide avermectin (AVM) and herbicide prometryn (PMT) are used as two models of hydrophobic pesticide and encapsulated within the porous microspheres, followed by a coating of tannic acid/iron (TA/Fe) complex films to generate two controlled-release pesticides, named as HCEAT and HCEPT, resulting in the loading capacity of AVM and PMT being 113.

Chitosan-based organic/inorganic composite engineered for UV light-controlled smart pH-responsive pesticide through in situ photo-induced generation of acid.

Background: Confined by the volatile property, pesticides are overused and lost significantly during and after spraying, weakening the ecological microbalance among different species of lives. Acid-responsive pesticide is a type of smartly engineered pesticides that contribute to the improvement of utilization efficiency of pesticidal active ingredients in acid-controlled manner, whilst the implementation of acidic solutions may disturb the balance of microenvironment surrounding targeted plants or cause secondary pollution, underscoring the input of acid in a more precise strategy.

Results: Chitosan was chemically modified with a photoacid generator (2-nitrobenzaldehyde) serving as a light-maneuvered acid self-supplier, based on which a smart pesticide was formulated by the integration of attapulgite and organophosphate insecticide chlorpyrifos.