Lactiplantibacillus plantarum extracellular vesicles exert anti-PEDV effects through STING-dependent autophagy.

Porcine epidemic diarrhea virus (PEDV) infection causes severe gastrointestinal and lethal disease in piglets, leading to huge economic losses for the swine industry worldwide. Recent studies have emphasized probiotics can regulate innate immunity and cellular functions through interaction with intestinal epithelial cells via extracellular vesicles (EVs) as effective carriers. The cGAS-STING signaling pathway is crucial for inducing type I interferons (IFNs) to establish antiviral innate immunity.

Proteomic analysis of wanxi white goose testicles in different reproductive stages by data-independent acquisition (DIA) strategy.

Wanxi white goose is an important male parent in crossbreeding of Chinese geese, but its short reproductive cycle restricts its application in Northeast China. Therefore, understanding the potential mechanism of breeding period regulation in Wanxi white goose will help to provide more options for crossbreeding. In this study, the reproductive period was divided into prophase (T1), metaphase (T2) and anaphase (T3) according to the laying rhythm of geese.

Deformation failure characteristics of coal body and mining induced stress evolution law.

The results of the interaction between coal failure and mining pressure field evolution during mining are presented. Not only the mechanical model of stope and its relative structure division, but also the failure and behavior characteristic of coal body under different mining stages are built and demonstrated. Namely, the breaking arch and stress arch which influence the mining area are quantified calculated.