Topological prethermal strong zero modes on superconducting processors.

Symmetry-protected topological phases cannot be described by any local order parameter and are beyond the conventional symmetry-breaking model. They are characterized by topological boundary modes that remain stable under symmetry respecting perturbations. In clean, gapped systems without disorder, the stability of these edge modes is restricted to the zero-temperature manifold; at finite temperatures, interactions with mobile thermal excitations lead to their decay.

Multi-modal Wearable Patch for Localized Monitoring of Post-operative Skin Flap Transplantation.

Monitoring the status of skin flap transplantation (SFT) is crucial for early intervention, particularly to mitigate risks, such as necrosis and complications arising from poor vascularization or infection. Current clinical practices for monitoring SFT rely on intermittent gauze removal, risking secondary injury and delayed complication detection. While wearable sensors have been proposed, existing systems lack simultaneous and multi-parameter monitoring, poor wearability, and the ability to localize complications within the flap.

Precise Gene Knock-In Tools with Minimized Risk of DSBs: A Trend for Gene Manipulation.

Gene knock-in refers to the insertion of exogenous functional genes into a target genome to achieve continuous expression. Currently, most knock-in tools are based on site-directed nucleases, which can induce double-strand breaks (DSBs) at the target, following which the designed donors carrying functional genes can be inserted via the endogenous gene repair pathway. The size of donor genes is limited by the characteristics of gene repair, and the DSBs induce risks like genotoxicity.