Nasal mucosa micronuclei as early biomarkers of effect in workers exposed to airborne pollutants: a literature overview.

Occupational exposure to air pollutants poses a serious health concern for workers, particularly due to potential genotoxic effects. The micronucleus (MN) test is widely recognized as a reliable biomarker of early genetic damage. Although commonly applied to lymphocytes or buccal epithelial cells, the nasal mucosa, being the first site of contact for inhaled toxicants, has received relatively limited attention.

Rehabilitative Good Practices in the Treatment of Patients with Muscle Injuries.

The rehabilitative treatment of muscle injuries is mostly conservative, but it does not always follow precise protocols. Appropriate physiotherapy, exercises, and training are essential components of the rehabilitation and reconditioning of injured muscles. The purpose of this review is to assess the good rehabilitative practices in the treatment of patients affected by muscle injuries.

Effects of dry needling on functioning and pain relief in patients with chronic nonspecific neck pain: a systematic review and meta-analysis of randomized controlled trials.

Purpose: Chronic nonspecific neck pain frequently causes disability and absence from work. The aim of this study was to assess the efficacy of dry needling (DN) on disability and pain in CNSNP patients.

Materials And Methods: We performed a systematic search on PubMed, Scopus, and Web of Science following the PRISMA guidelines.

Innovative Stem Cell Assisted Lipotransfer Approach for Breast Reconstruction in cancer Patients: Efficacy and Safety of the LIPO MULTI-SVF Study.

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Supplementary Information: The online version contains supplementary material available at 10.1007/s12015-025-10921-9.

Emotional Training After Facial Nerve Palsy: Let's Smile Again!

BackgroundWe aimed to propose () as a neurocognitive approach, based on motor imagery by stimulating the patient's perception through different stimuli on the face to treat peripheral paralysis of the facial nerve.MethodsRetrospective, observational, double-centres cohort study of 50 patients diagnosed with peripheral facial nerve palsy. Facial function was assessed through the House-Brackmann scale (HBS, the primary outcome), the Sunnybrook Facial Grading System (FGS, secondary outcome) and the Italian validated version of the Facial Disability Index (It-FDI, secondary outcome) at the beginning and the end of the rehabilitation protocol.

Evaluation of Sox4 levels in multiple myeloma patients.

Not available.

Microplastics as benzo-a-pyrene carriers: genotoxicity assessment simulating human gastric digestion.

Microplastic particles (MPs) are ubiquitous environmental pollutants that can remain in ecosystems for prolonged periods. Plastic materials undergo various degradation processes driven by chemical, physical, and biological factors that alter their size, shape, composition, and bioavailability. The gastrointestinal tract is the primary pathway through which MPs are absorbed, raising concerns as they can transport harmful pollutants and microorganisms into the body.

Effects of cerebellar transcranial alternating current stimulation on balance and gait in healthy subjects.

Background: Transcranial Alternating Current Stimulation (tACS) is a non-invasive brain stimulation technique that modulates cortical oscillations and influences behavior.

Objectives: This study aimed to explore the effects of cerebellar theta (5 Hz) and gamma (50 Hz) tACS on human balance and gait through kinematic analysis.

Materials And Methods: Nineteen right-handed healthy subjects participated in three randomized motor tasks: postural standing (PS), gait initiation (GI), and gait cycle (GC).

Pain, Function, and Elastosonographic Assessment After Shockwave Therapy in Non-Calcific Supraspinatus Tendinopathy: A Retrospective Observational Study.

Non-calcific supraspinatus tendinopathy (SNCCT) is a frequent cause of shoulder pain, often associated with functional impairment and reduced quality of life. Recent advancements in diagnostic imaging, including shear wave elastography (SWE), provide quantitative data on tendon stiffness and thickness, facilitating more precise evaluations. Extracorporeal shockwave therapy (ESWT) has emerged as a minimally invasive and effective treatment for SNCCT, but its effects on tendon properties measured through SWE require further investigation.

Effectiveness of ultrasound-guided hip injections on pain and functioning in patients with hip osteoarthritis: A systematic review.

Background: Osteoarthritis is the most common form of arthritis, causing pain, functional disability, and a reduction in terms of quality of life. Minimally invasive treatments like intra-articular hip injections are a therapeutic option and ultrasound guidance might improve the results of these injections.

Objective: To summarize the evidence about the effectiveness of ultrasound-guided hip injections in terms of pain and functioning in patients affected by hip osteoarthritis.

Temporomandibular joint arthritis in rheumatic diseases patients: which are the effective rehabilitative approaches for pain relief? A systematic review.

Background: Temporomandibular disorders (TMD) are a set of musculoskeletal conditions involving the temporomandibular joint, masticatory muscles, and/or associated structures, characterized by symptoms as pain, joint stiffness with limited mouth opening, and joint sounds as crepitus. Rheumatic diseases (RD) are a heterogeneous group of conditions affecting the musculoskeletal system, including temporomandibular joint (TMJ). To date, there is a lack of systematic reviews that properly investigated the efficacy of conservative approaches in reducing pain in rheumatic patients affected by TMJ arthritis.

The Role of Virtual Reality in Postural Rehabilitation for Patients with Parkinson's Disease: A Scoping Review.

Parkinson's disease is the second most common neurodegenerative disease worldwide, characterized by bradykinesia, rigidity, tremor, and postural instability. These symptoms often lead to significant postural deformities and an increased risk of falls, severely impacting the quality of life. Conventional rehabilitation methods have shown benefits, but recent advancements suggest that virtual reality (VR) could offer a promising alternative.

Patellofemoral Pain Syndrome: Focused Vibrations Plus Kinesiotaping with Insights into Radiological Influences-An Observational Study.

Background: This observational study investigates the efficacy of combining local muscle vibration (LMV) therapy and kinesiotaping using the McConnell method (KMcCM) in patients with patellofemoral pain syndrome (PFPS). PFPS is a prevalent knee condition characterized by anterior or medial knee pain exacerbated by activities that overload the patellofemoral joint.

Objective: The primary aim of this study was to evaluate the effectiveness of LMV combined with KMcCM in reducing pain and improving function in PFPS patients.

Evaluation of Rehabilitation Outcomes in Patients with Chronic Neurological Health Conditions Using a Machine Learning Approach.

Over one billion people worldwide suffer from neurological conditions that cause mobility impairments, often persisting despite rehabilitation. Chronic neurological disease (CND) patients who lack access to continuous rehabilitation face gradual functional decline. The International Classification of Functioning, Disability, and Health (ICF) provides a comprehensive framework for assessing these patients.

The Spread of from Heater-Cooler Units and Infection Risk in Heart Surgery: Lessons from the Global Outbreak?

(MC), a member of the complex, can cause infections in patients after open-heart surgery due to contaminated heater-cooler units (HCUs). The transmission route of HCU-related MC infection is non-inhalational, and infection can occur in patients without previously known immune deficiency. Patients may develop endocarditis of the prosthetic valve, infection of the vascular graft, and/or manifestations of disseminated mycobacterial infection (splenomegaly, arthritis, hepatitis, nephritis, myocarditis, etc.

The Effect of Intra-Articular Injections of Hyaluronic Acid for the Treatment of Trapezio-Metacarpal Joint Osteoarthritis.

Background: Osteoarthritis of the basal thumb joint is a debilitating disease with a high prevalence. Among pharmacological treatments, intra-articular injections of hyaluronic acid have been clinically applied. This study aimed to investigate the effectiveness and safety of intra-articular injections of hyaluronic acid for the treatment of trapezio-metacarpal joint osteoarthritis (TMOA), over a one-year period.

Iron Dyshomeostasis in Neurodegeneration with Brain Iron Accumulation (NBIA): Is It the Cause or the Effect?

Iron is an essential metal ion implicated in several cellular processes. However, the reactive nature of iron renders this metal ion potentially dangerous for cells, and its levels need to be tightly controlled. Alterations in the intracellular concentration of iron are associated with different neuropathological conditions, including neurodegeneration with brain iron accumulation (NBIA).

Identifying discriminant factors between phantom limb pain, residual limb pain, and both in people with lower limb amputations: a cross-sectional study.

Postamputation pain is a common condition in patients with lower limb amputation (LLA), which compromises amputees' rehabilitation, use of the prosthesis, and quality of life. The aim of our study was to investigate the prevalence of phantom limb pain (PLP), residual limb pain (RLP), or both types of pain among individuals with LLA, and to identify the factors associated with the presence of one type of pain versus the other. Patients who underwent amputation for traumatic or vascular reasons and who reported on RLP or PLP were analyzed and divided into three groups: PLP, RLP, or a group of subjects that presented both pains.

Predictive Prognostic Factors in Non-Calcific Supraspinatus Tendinopathy Treated with Focused Extracorporeal Shock Wave Therapy: An Artificial Neural Network Approach.

The supraspinatus tendon is one of the most involved tendons in the development of shoulder pain. Extracorporeal shockwave therapy (ESWT) has been recognized as a valid and safe treatment. Sometimes the symptoms cannot be relieved, or a relapse develops, affecting the patient's quality of life.

UVB-Aged Microplastics and Cellular Damage: An in Vitro Study.

Plastics are synthetic organic compounds whose widespread use generates enormous waste. Different processes, such as mechanical abrasion, microbiological activity, and UVB irradiation, can fragment the plastic material and generate microplastics (MPs). MPs are ubiquitous, and various organisms, including humans, can ingest or inhale them, with potential adverse health effects.

expansion in a clinical grade medium, containing growth factors from human platelets, enhances migration capacity of adipose stem cells.

Introduction: Adipose tissue mesenchymal stem/stromal cells (ASC) can be used as advanced therapy medicinal product in regenerative and cancer medicine. We previously demonstrated Supernatant Rich in Growth Factors (SRGF) can replace fetal bovine serum (FBS) to expand ASC by a clinical grade compliant protocol. The therapeutic potential of ASC is based also on their homing capacity toward inflammatory/cancer sites: oriented cell migration is a fundamental process in this scenario.