Publications by authors named "Fatima Mujahid"
Background: Urinary tract infections (UTIs), primarily caused by Escherichia coli, pose a global health challenge owing to rising antimicrobial resistance (AMR), particularly carbapenem-resistant (Carb-RT) and extended-spectrum beta-lactamase (ESBL)-producing uropathogenic E. coli (UPEC). This study analyzed AMR trends, virulence determinants, and molecular epidemiology of UPEC isolates from community and hospital settings in Pakistan.
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- Urinary tract infections (UTIs) in hospitals are often caused by uropathogenic E. coli (UPEC), and the rise of carbapenem-resistant strains poses a serious public health threat due to their resistance to multiple drugs and virulence factors.
- This study analyzed 1,100 urine samples from patients in Pakistan to identify and characterize carbapenem-resistant UPEC strains, using various microbiological techniques to evaluate their antimicrobial resistance and virulence genes.
- The results showed high resistance rates to sulfamethoxazole-trimethoprim and doxycycline, with certain sequence types (ST405 and ST167) being prevalent among the resistant strains, emphasizing the need for better surveillance and
Article Synopsis
- The study highlights a significant prevalence of nasal carrier rates of Staphylococcus aureus among students, with 14% overall, including 5.5% methicillin-resistant Staphylococcus aureus (MR-SA).
- The research identified a higher prevalence in male and urban students, and revealed alarming antimicrobial resistance trends, with 80.3% of isolates resistant to erythromycin and other antibiotics, but maintained susceptibility to vancomycin and linezolid.
- PCR analysis indicated that a majority of MR-SA isolates carried the mecA gene, raising concerns about multi-drug resistance and public health implications.