Publications by authors named "Farid Fotouhi"

Purpose: To determine the prevalence of hypertension in a population above 60 years of age and its relationship with demographic and anthropometric factors.

Methods: A cross-sectional population-based study was conducted in 2019. Using a multistage random cluster sampling, 160 clusters were selected from 22 districts of Tehran.

View Article and Find Full Text PDF

3-acetylpyridine (3-AP) is a neurotoxin that is known to mainly affect the inferior olivary nucleus (ION) in the brain stem. Although several studies have explored the effect of this neurotoxin, still further investigation is required to understand the impact of this toxin on different parts of the brain. In this research, two groups of rats were studied, the 3-AP-treated and the control groups.

View Article and Find Full Text PDF

The present study was designed to evaluate whether elderberry (EB) effectively reduces inflammation and oxidative stress in hippocampal cells to modify seizure damage. Seizure was induced in rats by the injection of pentylenetetrazol (PTZ). In the Seizure + EB group, EB powder was added to the rats' routine diet for eight consecutive weeks.

View Article and Find Full Text PDF

Purpose: To determine the distribution of blood glucose and prevalence of diabetes in people above 60 years living in Tehran and their relationship with some variables.

Methods: In this cross-sectional population-based study, multistage cluster sampling was performed in the over 60-year-old population of Tehran. Blood samples were collected from all participants and the data of the history of diabetes and the use of blood glucose lowering agents or other drugs were collected using interviews.

View Article and Find Full Text PDF

Huntington's disease (HD) is an inherited neurodegenerative disorder which begins in the striatum and then spreads to other neural areas. Known as a progressive movement cognitive disorder, HD has no efficient therapy. Although the exact mechanism of HD is still unknown, several different etiological processes such as oxidative stress have been shown to play critical roles.

View Article and Find Full Text PDF
Article Synopsis
  • ADHD is a prevalent developmental disorder, often treated with Methylphenidate (MPH), but concerns about its side effects on brain development are rising.
  • This study aimed to investigate the negative effects of MPH on the hippocampus of rats using various behavioral and biochemical tests.
  • Results showed that MPH reduced rats' willingness to explore new environments and did not improve memory or learning, while also increasing astrogliosis in the hippocampus, highlighting the need for further research on MPH's impact on brain health.
View Article and Find Full Text PDF