Publications by authors named "Fang-Wei Wu"

is a zoonotic parasitic disease caused by the larval stage of the parasite Echinococcus, which has a long incubation period, expensive diagnosis and treatment, and long duration of medication, so it brings a great economic burden to patients and their families. Shangri-La City is one of the counties with a high prevalence of echinococcosis in Yunnan Province. The antigen-positive rate of Echinococcus feces is high and there is a potential risk of infecting people.

View Article and Find Full Text PDF
Article Synopsis
  • Echinococcosis is widespread in Western and Northern China, particularly in Yunnan Province, where cases were documented in epidemiological surveys conducted in 2012 and 2016.
  • The study aimed to assess the spatial distribution and characteristics of echinococcosis cases in Yunnan, collected through reports from hospitals and disease control centers between 2021-2022.
  • Findings revealed 397 analyzed cases across 89 counties in Yunnan, with the highest incidences in Dali, Diqing, and Kunming, highlighting significant regional differences and a low overall case reporting rate.
View Article and Find Full Text PDF
Article Synopsis
  • A study looked at how effective using a patient's own blood after knee surgeries really is.
  • It compared two groups of patients: one that got their own blood back and one that didn't.
  • The results showed that using the patient's own blood didn't lower the need for other blood transfusions and actually made the hospital stay longer and costs higher.
View Article and Find Full Text PDF
Article Synopsis
  • A study aimed to determine if hearing thresholds assessed via auditory brainstem response (ABR) in infants can predict behavioral pure-tone audiometry (PTA) thresholds in children, using data from a newborn hearing screening program in Taiwan.
  • The research included 104 newborns, focusing on their ABR thresholds and subsequent PTA thresholds, analyzed through correlation and regression methods.
  • Results showed a strong correlation (0.76) between ABR and PTA thresholds, suggesting that while ABR can provide a reliable estimate for behavioral PTA in many cases, it is recommended to combine different ABR methods for precise hearing aid fittings and rehabilitation.
View Article and Find Full Text PDF

The multi-dimensional nature of pain renders difficult a holistic understanding of it. The conceptual framework of pain is said to be cognitive-evaluative, in addition to being sensory-discriminative and affective-motivational. To compare participants' brain-behavior response before and after a 6-week mindfulness-based stress reduction training course on mindfulness in relation to pain modulation, three questionnaires (the Dallas Pain Questionnaire, Short Form McGill Pain Questionnaire-SFMPQ, and Kentucky Inventory of Mindfulness) as well as resting-state functional magnetic resonance imaging were administered to participants, divided into a pain-afflicted group ( = 18) and a control group ( = 16).

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess the prevalence of soil-transmitted nematode infections in Xiding Township, Menghai County, to help shape control strategies.
  • It utilized the Kato-Katz and cellophane tape methods to detect nematode eggs in feces and soil samples from local crop fields, finding a 20.06% infection rate among 1,002 residents.
  • Results indicated a high infection rate but mostly light infections, highlighting the need for improved monitoring and control measures in the area.
View Article and Find Full Text PDF

Background: The aim was to evaluate the effect of comprehensive intensive therapy on the carotid and femoral arteries of intima-media thickness in patients with type 2 diabetes mellitus after 4-year follow-up.

Methods: In this prospective 4-year study, patients (N = 210) with newly diagnosed type 2 diabetes received either comprehensive intensive therapy (n = 110) or conventional therapy (n = 100). Blood pressure, blood glucose and lipid levels were monitored every 3-6 months, and carotid and femoral arteries of intima-media thickness were monitored with ultrasonography.

View Article and Find Full Text PDF

Objective: To understand the status of Toxoplasma gondii infection in the population of Pu'er City, so as to provide the evidence for formulating the strategy of toxoplasmosis control.

Methods: The population from Jingdong, Jinggu, and Menglian counties in Pu' er City was surveyed; IgG of T. gondii in serum was detected by ELISA.

View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on controlling soil-transmitted helminthiasis in Menghai county, China, emphasizing that relying solely on drug administration does not tackle underlying social and ecological factors.
  • Improvements in water, sanitation, and hygiene, combined with health education, are highlighted as essential for long-term control of infections.
  • The most effective intervention was bi-annual deworming paired with sanitation upgrades and health education, achieving significant reductions in infection prevalence compared to other methods.
View Article and Find Full Text PDF

Background: There is considerable debate on the health impacts of soil-transmitted helminth infections. We assessed effects of deworming on physical fitness and strength of children in an area in Yunnan, People's Republic of China, where soil-transmitted helminthiasis is highly endemic.

Methodology: The double-blind, randomized, placebo-controlled trial was conducted between October 2011 and May 2012.

View Article and Find Full Text PDF

Post-traumatic stress disorder (PTSD) is a debilitating anxiety disorder that may develop after an individual has experienced or witnessed a severe traumatic event. It has been shown that the 18 kDa translocator protein (TSPO) may be correlated with PTSD and that the TSPO ligand improved the behavioral deficits in a mouse model of PTSD. Midazolam, a ligand for TSPO and central benzodiazepine receptor (CBR), induces anxiolytic- and anti-depressant-like effects in animal models.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers are studying a new way to help people with a serious leg problem called critical limb ischemia by using gene therapy.
  • They looked at different studies to see if gene therapy worked better than a fake treatment (placebo) for patients who couldn't have surgery.
  • The results showed that gene therapy didn't help much more than the placebo in preventing amputations, deaths, or healing wounds after 6 months.
View Article and Find Full Text PDF

Posterior spinal instrumentation and fusion surgery in school-aged children and adolescents is associated with the potential for massive intraoperative blood loss, which requires significant allogeneic blood transfusion. Until now, the intraoperative use of the cell saver has been extensively adopted; however, its efficacy and cost-effectiveness have not been well established. Therefore, the aim of this study is to determine the efficacy and cost-effectiveness of intraoperative cell saver use.

View Article and Find Full Text PDF

Corticosterone inhibits the proliferation of hippocampal neural stem cells (NSCs). The removal of corticosterone-induced inhibition of NSCs proliferation has been reported to contribute to neural regeneration. Leptin has been shown to regulate brain development, improve angiogenesis, and promote neural regeneration; however, its effects on corticosterone-induced inhibition of NSCs proliferation remain unclear.

View Article and Find Full Text PDF

Post-treatment soil-transmitted helminth re-infection patterns were studied as part of a randomized controlled trial among school-aged children from an ethnic minority group in Yunnan province, People's Republic of China. Children with a soil-transmitted helminth infection (N = 194) were randomly assigned to triple-dose albendazole or placebo and their infection status monitored over a 6-month period using the Kato-Katz and Baermann techniques. Baseline prevalence of Trichuris trichiura, Ascaris lumbricoides, hookworm, and Strongyloides stercoralis were 94.

View Article and Find Full Text PDF

Background: Chronic soil-transmitted helminth (STH) infections have been associated with reduced physical fitness, but available evidence is limited. The aim of this cross-sectional survey was to assess the feasibility of measuring children's physical fitness and to relate it to STH infections. Our study was carried out among school-aged children of the Bulang ethnic group in rural southwest People's Republic of China (P.

View Article and Find Full Text PDF

In the national monitoring point, Menghai County, Yunnan Province, the total prevalence rate of soil-transmitted nematode infections was 88.12%, of which the rates of Ascaris lumbricoides, Trichuris trichiura, hookworm and cestode infections were 69.70%, 59.

View Article and Find Full Text PDF

Objective: This study aimed to estimate the efficacy and tolerability of the combination of amlodipine and angiotensin-converting enzyme inhibitors as compared with amlodipine monotherapy in the treatment of hypertension.

Methods: The Cochrane Central Register of Controlled Trials, PubMed, and Embase were searched for relevant articles. A random effect model of meta-analysis was used for the selected randomized controlled trials (RCTs).

View Article and Find Full Text PDF

Objective: To investigate the characteristics of medical support and health care for the Shenzhou-5 and Shenzhou-6 astronauts at the main landing site, with special emphasis on the technical requirements for two astronauts during flight, in order to provide reference data for medical support in the battle field and disasters.

Methods: The data associated with accidental injuries of astronauts during the space flight collected from foreign nations and domestically were reviewed retrospectively. Based on the experience in medical support for Shenzhou-5 and Shenzhou-6 astronauts and the special environments of field operations, a scheme for first-aid and emergent treatment were drafted for a system of organization, prophylactic measurements, equipment and their effective implementation pending the test in the real situation.

View Article and Find Full Text PDF

Objective: To discuss the experience of establishment of a mobile intensive care unit (ICU) for emergency treatment following astronaut flight, disaster, and regional war.

Methods: The data from both foreign and our countries as well as our own clinical experience of first-aid were reviewed, and a mobile ICU was established, including the equipment, supply of drugs, training, and organization.

Results: The mobile ICU was set up at the site of landing of the first Chinese astronaut, and proved to be efficient.

View Article and Find Full Text PDF

Objective: To discuss the experience of medical care and rescue for the first Chinese astronaut during manned space flight.

Methods: Review the experiences of foreign nations in respect to accidental injuries of astronaut during manned space flight, the possible reasons were analyzed, and accordingly a reasonable and effective prophylactic measures and health care were formulated.

Results: An effective mobile intensive care unit (ICU) was established on desert or prairie where the capsule would land, so as to ensure the safety of the first Chinese astronaut, and to provide intensive care as well as successful emergency treatment in case of accidental injuries.

View Article and Find Full Text PDF