Cost-Effectiveness of Hominis Placenta Therapy for Chronic Temporomandibular Disorder: An Economic Evaluation Alongside a Pragmatic Randomised Controlled Trial.

Background: Hominis placenta (HP) exhibits anti-inflammatory, antiviral and nerve growth-promoting properties; however, there are limited studies about HP therapy in the treatment of temporomandibular disorder (TMD).

Objective: To evaluate the cost-effectiveness of HP therapy with that of physical therapy (PT) in patients with TMD.

Methods: This cost-effectiveness analysis was conducted alongside a 26-week multicentre pragmatic randomised controlled trial (RCT).

Effectiveness and safety of hominis placental pharmacopuncture for chronic temporomandibular disorder: A multi-center randomized controlled trial.

Background: Hominis placental (HPP) extract has been approved by the Ministry of Food and Drug Safety in Korea for treating chronic liver diseases and postmenopausal syndrome. However, its efficacy and safety for treating chronic temporomandibular disorder (TMD) remains unclear. We aimed to assess the effectiveness and safety of HPP for treating chronic TMD compared with physical therapy (PT).

Minimum clinically important difference and substantial clinical benefit in patients with chronic temporomandibular disorders.

Background: Research on temporomandibular disorder (TMD) responsiveness is scarce and limited regarding patients' representativeness.

Objective(s): This study aimed to estimate minimum clinically important difference (MCID) and substantial clinical benefit (SCB) among a large and diverse patient population regarding sex and age.

Methods: In this study, 162 patients participated from five hospitals.

Effectiveness of lumbar motion style acupuncture treatment on inpatients with acute low back pain: A pragmatic, randomized controlled trial.

Background And Purpose: This parallel, single-center, pragmatic, randomized controlled study aimed to investigate the effectiveness and safety of motion style acupuncture treatment (MSAT; a combination of acupuncture and Doin therapy) to reduce pain and improve the functional disability of patients with acute low back pain (aLBP) due to road traffic accidents.

Materials And Methods: Ninety-six patients with aLBP admitted to the Haeundae Jaseng Hospital of Korean Medicine in South Korea due to traffic accidents were treated with integrative Korean medicine (IKM) with additional 3-day MSAT sessions during hospitalization (MSAT group, 48 patients) or without (control group, 48 patients), and followed up for 90 days.

Results: The mean numeric rating scale (NRS) scores of low back pain (LBP) of the MSAT and control groups were both 6.

An economic evaluation of pharmacopuncture versus usual care for chronic neck pain: a pragmatic randomized controlled trial.

Background: This study aimed to evaluate the cost utility of pharmacopuncture in comparison with usual care for patients with chronic neck pain.

Methods: A 12-week, multicenter, pragmatic randomized controlled trial was conducted, and 101 patients suffering from chronic neck pain for more than six months were randomly placed into the pharmacopuncture and usual care groups to receive four weeks of treatment and 12 weeks of follow-up observations. The quality-adjusted life year (QALY) was calculated using EQ-5D and SF-6D.

Long-term follow-up of inpatients with traumatic fractures who received integrative Korean Medicine treatment: A retrospective analysis and questionnaire survey study.

Previous studies have reported pain reduction after Korean medicine (KM) treatment in patients with fractures. However, these studies were limited by small sample sizes and short observation periods. To address these limitations, we aimed to analyze the outcomes of patients with traumatic fractures who received integrative KM treatment and investigate their long-term progress through follow-up observations.

A Pilot Study for Effectiveness of Non-Pharmacological versus Pharmacological Treatment Strategies for Lumbar Disc Herniation: A Pragmatic Randomized Controlled Trial.

Purpose: We aimed to compare the efficacy, safety, and cost-effectiveness of non-pharmacological- and pharmacological treatment strategies for Lumbar disc herniation (LDH) in pragmatic clinical settings.

Patients And Methods: This study was a pilot, two-armed, parallel pragmatic randomized controlled trial. Thirty patients aged 19-70 years with a numeric rating scale (NRS) score ≥5 for sciatica and confirmed LDH on magnetic resonance imaging (MRI) were included.

Consistency of dose rates after applying machine-specific reference correction factors for the gamma knife 16 mm collimator field.

Background: The machine-specific reference (msr) correction factors ( ) were introduced in International Atomic Energy Agency (IAEA) Technical Report Series 483 (TRS-483) for reference dosimetry of small fields. Several correction factor sets exist for a Leksell Gamma Knife (GK) Perfexion or Icon. Nevertheless, experiments have not rigorously validated the correction factors from different studies.

The Impact of Moderate Earthquakes on Antidepressant Prescriptions in Ulsan, South Korea: A Controlled Interrupted Time Series Analysis.

Background: In 2016, two consecutive moderate magnitude earthquakes occurred in Ulsan, South Korea. Therefore, we aimed to investigate the impact of earthquakes on the mental health of residents in Ulsan.

Methods: We used data from the 2015-2017 Korean Health Insurance Review & Assessment Service National Patient Sample.

Cost-Utility Analysis of Chuna Manual Therapy and Usual Care for Chronic Neck Pain: A Multicenter Pragmatic Randomized Controlled Trial.

This study aimed to compare the cost-effectiveness of manual therapy and usual care for patients with chronic neck pain. A cost-utility analysis alongside a pragmatic randomized controlled trial was conducted in five South Korean hospitals. Data were procured from surveys and nationally representative data.

A Time-Dependent Analysis of Association between Acupuncture Utilization and the Prognosis of Ischemic Stroke.

This study investigated the time-dependent characteristics of acupuncture and analyzed the association between acupuncture utilization and mortality rates, readmission rates, and complications among ischemic stroke patients. Data from the National Health Insurance Service-National Sample Cohort 2.0 from South Korea were used to track patients with subacute and chronic ischemic stroke, who had survived more than one month after onset, between 2010 and 2013.

Treatment for temporomandibular disorders in South Korea: A 9-year trend using cluster analysis.

Background: Despite the availability of clinical practice guidelines for temporomandibular disorders (TMDs), research evidence on current clinical practice trends is scarce.

Objective: This study aimed to analyse the TMD treatment trends and patterns according to patient characteristics in Korea over a 9-year period.

Methods: The 2010-2018 Korean Health Insurance Review & Assessment Service National Patient Sample data were used.

Long-Term Follow-Up of Inpatients with Cervical Myelopathy Who Received Integrative Korean Medicine Treatment: A Retrospective Analysis and Questionnaire Survey Study.

Purpose: Cervical myelopathy (CM) is generally considered an indication for surgery in Western medicine. Case reports have indicated that Korean medicine (KM) treatments are effective in improving CM-associated symptoms. We investigated the effectiveness of non-surgical KM treatment of CM patients through a retrospective chart review and follow-up survey.

Effectiveness and safety of motion style acupuncture treatment of the pelvic joint for herniated lumbar disc with radiating pain: A prospective, observational pilot study.

Context: Conservative treatment is effective for treating and managing herniated lumbar disc with radiating leg pain.

Objectives: To investigate the effects of motion style acupuncture treatment (MSAT) on the pelvic joint for this condition.

Design: This prospective observational study was a pilot study for a future randomized, controlled trial (RCT).

Prescription rate and treatment patterns for allergic rhinitis from 2010 to 2018 in South Korea: a retrospective study.

Background: There has been little investigation on how guidelines for allergic rhinitis (AR) treatment are applied in current clinical practice. We aimed to analyze prescription trends and patterns for AR treatment according to patient characteristics over a 9-year period in Korea.

Methods: We used cross-sectional data from the Korean Health Insurance Review & Assessment Service National Patient Sample from 2010 to 2018.

Association between pain and gait instability in patients with lumbar disc herniation.

Objective: To determine whether pain is associated with gait instability in patients with lumbar disc herniation (LDH).

Methods: This retrospective cross-sectional study used data from electronic medical records. Among patients with lumbar back pain caused by LDH between January 2017 and July 2019, patients that underwent gait analysis were included.

The association between continuity of care and surgery in lumbar disc herniation patients.

Continuity of care is a core dimension of high-quality care in the management of disease. The purpose of this study was to investigate the association between continuity of care and lumbar surgery in patients with moderate disc herniation. The Korean National Sample Cohort was used.

The effect of continuity of care on medical costs in patients with chronic shoulder pain.

Unnecessary surgery could be prevented through continuity of care (COC). The present study aimed to investigate the relationships between COC, surgery and cost associated with chronic shoulder pain. We used the Health Insurance Review and Assessment Service national patient sample (HIRA-NPS) in 2017.

Association between blood cadmium levels and the risk of osteopenia and osteoporosis in Korean post-menopausal women.

Unlabelled: We aimed to investigate the association between cadmium levels and the risk of osteopenia and osteoporosis in Korean post-menopausal women. There was a significant positive association between cadmium levels and the risk of osteopenia and osteoporosis, but further studies for dose response are required.

Purpose: Cadmium exposure can exert detrimental effects on bone health, particularly in post-menopausal women.

Therapeutic Effects of Licorice and Dried Ginger Decoction on Activity-Based Anorexia in BALB/c AnNCrl Mice.

Licorice and dried ginger decoction (Gancao-ganjiang-tang, LGD) is used for nausea and anorexia, accompanied by excessive sweating in Traditional Chinese Medicine. Herein, we investigated the therapeutic effects of LGD using the activity-based anorexia (ABA) in a mouse model. Six-week-old female BALB/c AnNCrl mice were orally administered LGD, water, licorice decoction, dried ginger decoction, or chronic olanzapine, and their survival, body weight, food intake, and wheel activity were compared in ABA.

Measurement of bunch length and temporal distribution using accelerating radio frequency cavity in low-emittance injector.

We demonstrate an experimental methodology for measuring the temporal distribution of pico-second level electron bunch with low energy using radial electric and azimuthal magnetic fields of an accelerating ([Formula: see text] mode) radio frequency (RF) cavity that is used for accelerating electron beams in a linear accelerator. In this new technique, an accelerating RF cavity provides a phase-dependent transverse kick to the electrons, resulting in the linear coupling of the trajectory angle with the longitudinal position inside the bunch. This method does not require additional devices on the beamline since it uses an existing accelerating cavity for the projection of the temporal distribution to the transverse direction.

Association between osteoarthritis and unmet medical needs in Korea: limitations in activities as a mediator.

Background: The role of limitations in activities in relation to unmet needs is not clarified. This study aimed to analyze the effects of osteoarthritis on unmet medical needs and the mediating effects of limitations in activities.

Methods: A total number of 10,129 population aged ≥50 years were included using data from the Korean National Health and Nutrition Examination Survey from January 2010 to December 2013.

Design of compact accelerator system for high flux accelerator based neutron source.

Accelerator Based Neutron Sources (ABNS) have been studied for their utility in materials research as well as for boron neutron captured therapy. By making significant efforts to study the (p,n) and (d,n) nuclear reactions, the specifications of the accelerator system have been determined. In this paper, we compare the design results for two types of radio frequency quadrupole (RFQ) accelerators to provide proton and deuteron beams, respectively.