Correlation of fecal calprotectin levels with the detection of treatable enteric pathogens in children with severe acute diarrheal disease in Botswana.

Diarrheal disease is a leading cause of death among young children globally. Current guidelines recommend supportive treatment of acute diarrhea and using antimicrobials only with presence of blood in the stool. Select enteric pathogens, including Shigella, commonly cause disease in high-burden settings; targeted treatment of these pathogens could decrease morbidity and mortality.

Acute histoplasmosis in four immunocompetent Canadian travellers to a cenote in Yucatán, Mexico.

A group of four healthy Canadian travellers visited a cenote in the Yucatán peninsula in April 2024 and subsequently developed symptomatic histoplasmosis. Diagnosis was made in the acute period with a positive urine antigen test in three of the cases. Two developed severe presentations and were treated with itraconazole, including a three-year-old child with disseminated disease.

Prevalence and characterization of food insecurity in a Canadian paediatric emergency department.

Objectives: Food insecurity (FI) is associated with a number of adverse child health outcomes and increased emergency department (ED) use. The COVID-19 pandemic exacerbated the financial hardship faced by many families. We sought to determine the prevalence of FI among children with ED visits, compare this to pre-pandemic rates, and describe associated risk factors.