Publications by authors named "Ekaterina Pazukhina"
Background And Objective: Magnetic resonance imaging (MRI)-driven active surveillance (AS) is increasingly used for management of prostate cancer (PC). The aim of our study was to determine the oncological safety of contemporary MRI-driven AS and identify patients at higher risk of AS failure.
Methods: This retrospective cohort study included AS patients with MRI-localised PC from three US and UK centres.
Background: The COVID-19 pandemic has led to widespread long-term complications, known as post-COVID conditions (PCC), particularly affecting vulnerable populations such as cancer patients. This study aims to predict the incidence of PCC in hospitalised cancer patients using the data from a longitudinal cohort study conducted in four major university hospitals in Moscow, Russia.
Methods: Clinical data have been collected during the acute phase and follow-ups at 6 and 12 months post-discharge.
: Respiratory viral infections (RVIs) exhibit seasonal patterns influenced by biological, ecological, and climatic factors. Weather variables such as temperature, humidity, and wind impact the transmission of droplet-borne viruses, potentially affecting disease severity. However, the role of climate in predicting complications in pediatric RVIs remains unclear, particularly in the context of climate-change-driven extreme weather events.
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- A study investigated the global prevalence of Long Covid symptoms in individuals from high-income countries (HICs) and low- to middle-income countries (LMICs), since most previous research focused on HICs.
- The research involved 11,860 participants from 17 countries, examining symptoms like fatigue, breathlessness, and their impact on daily life at various time points after hospitalization.
- Findings revealed a significantly higher proportion of Long Covid cases and associated symptoms in HICs compared to LMICs, suggesting that while LMICs have lower reported rates, the overall impact of Long Covid might still be significant due to healthcare disparities.
Background: IgE-mediated food allergy (FA) is a global health concern with substantial individual and societal implications. While diverse intervention strategies have been researched, inconsistencies in reported outcomes limit evaluations of FA treatments. To streamline evaluations and promote consistent reporting, the Core Outcome Measures for Food Allergy (COMFA) initiative aimed to establish a Core Outcome Set (COS) for FA clinical trials and observational studies of interventions.
View Article and Find Full Text PDFEvent rates and incidence of post-COVID-19 condition in hospitalised SARS-CoV-2 positive children and young people and controls across different pandemic waves: exposure-stratified prospective cohort study in Moscow (StopCOVID).
BMC Med
February 2024
Article Synopsis
- - The study aimed to explore long-term health outcomes in children and young people post-COVID-19, particularly focusing on post-COVID-19 condition (PCC) and incomplete recovery, comparing these outcomes with those from other non-SARS-CoV-2 infections.
- - Conducted in Moscow, researchers followed two cohorts of pediatric patients with confirmed COVID-19 from two different time periods (Wuhan and Omicron variants) and compared them to a reference group of those with other infections but negative for SARS-CoV-2.
- - Findings revealed that the incidence of PCC was significantly higher in the Wuhan variant group compared to the reference group, while the Omicron variant showed no significant difference in PCC outcomes when compared to the
Background: Multisystem inflammatory syndrome in children (MIS-C), a hyperinflammatory condition associated with SARS-CoV-2 infection, has emerged as a serious illness in children worldwide. Immunoglobulin or glucocorticoids, or both, are currently recommended treatments.
Methods: The Best Available Treatment Study evaluated immunomodulatory treatments for MIS-C in an international observational cohort.
Previous studies assessing the prevalence of COVID-19 sequelae in children have included either a small number of children or a short follow-up period, or have only focused on hospitalized children. We investigated the prevalence of persistent symptoms amongst children and assessed the risk factors, including the impact of variants. A prospective cohort study included children (≤18 years old) with PCR-confirmed SARS-CoV-2 infection.
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- - The study investigated the prevalence of post-COVID-19 condition (PCC) in adults and children who were hospitalized after contracting COVID-19, using a defined WHO standard and conducting follow-ups at 6 and 12 months post-discharge.
- - Findings showed a PCC prevalence of 50% in adults and 20% in children at 6 months, decreasing to 34% and 11%, respectively, at 12 months; factors such as female sex and hypertension in adults, and neurological comorbidities in children were linked to higher PCC risk.
- - The results highlight the importance of monitoring for ongoing health issues following COVID-19, particularly in higher-risk groups, as a significant number of individuals experienced
Background: Emerging evidence shows that both adults and children may develop post-acute sequelae of SARS-CoV-2 infection (PASC). The aim of this study is to characterise and compare long-term post-SARS-CoV-2 infection outcomes in adults and children in a defined region in Italy.
Methods: A prospective cohort study including children (≤18 years old) with PCR-confirmed SARS-CoV-2 infection and their household members.