Publications by authors named "Mikhail Rumyantsev"
Background: The COVID-19 pandemic has led to widespread long-term complications, known as post-COVID conditions (PCC), particularly affecting vulnerable populations such as cancer patients. This study aims to predict the incidence of PCC in hospitalised cancer patients using the data from a longitudinal cohort study conducted in four major university hospitals in Moscow, Russia.
Methods: Clinical data have been collected during the acute phase and follow-ups at 6 and 12 months post-discharge.
The original method for the preparation of high-molecular-weight polyalkylene sulfides was reported. Assuming anomalous peculiarities of the reaction (high polymerization rates, high degrees of polymerization, and huge discrepancy between the expected values and the experimentally obtained values), the priority task was set to study the mechanism underlying the observed new type of polymerization. Thus, it was demonstrated that xanthate and related molecules could act as pure catalysts, facilitating both the chain-growth polymerization (ring-opening of episulfides) realized via an anionic route and the direct attack of the sulfur atom of one episulfide molecule on the methylene carbon atom of the second (neighbor) episulfide molecule, accompanied by the subsequent formation of a stable thiiranium-based zwitterionic adduct.
View Article and Find Full Text PDFEvent rates and incidence of post-COVID-19 condition in hospitalised SARS-CoV-2 positive children and young people and controls across different pandemic waves: exposure-stratified prospective cohort study in Moscow (StopCOVID).
BMC Med
February 2024
Article Synopsis
- - The study aimed to explore long-term health outcomes in children and young people post-COVID-19, particularly focusing on post-COVID-19 condition (PCC) and incomplete recovery, comparing these outcomes with those from other non-SARS-CoV-2 infections.
- - Conducted in Moscow, researchers followed two cohorts of pediatric patients with confirmed COVID-19 from two different time periods (Wuhan and Omicron variants) and compared them to a reference group of those with other infections but negative for SARS-CoV-2.
- - Findings revealed that the incidence of PCC was significantly higher in the Wuhan variant group compared to the reference group, while the Omicron variant showed no significant difference in PCC outcomes when compared to the
Background: Even though the incidence of Multisystem Inflammatory Syndrome in children (MIS-C) is decreasing cases are still reported across the world. Studying the consequences of MIS-C enhances our understanding of the disease's prognosis. The objective of this study was to assess short- and medium-term clinical outcomes of MIS-C.
View Article and Find Full Text PDFPrevalence and risk factors of post-COVID-19 condition in adults and children at 6 and 12 months after hospital discharge: a prospective, cohort study in Moscow (StopCOVID).
BMC Med
July 2022
Article Synopsis
- - The study investigated the prevalence of post-COVID-19 condition (PCC) in adults and children who were hospitalized after contracting COVID-19, using a defined WHO standard and conducting follow-ups at 6 and 12 months post-discharge.
- - Findings showed a PCC prevalence of 50% in adults and 20% in children at 6 months, decreasing to 34% and 11%, respectively, at 12 months; factors such as female sex and hypertension in adults, and neurological comorbidities in children were linked to higher PCC risk.
- - The results highlight the importance of monitoring for ongoing health issues following COVID-19, particularly in higher-risk groups, as a significant number of individuals experienced