Traditional biophysical cytometry has been limited by its low-dimensional phenotyping characteristics, often relying on only one or a few cellular biophysical phenotypes as readouts. This has perpetuated the perception that biophysical cytometry lacks the power to determine cellular heterogeneity. Here, we introduce a multimodal biophysical cytometry platform, termed quantitative phase morpho-rheological (QP-MORE) cytometry, which simultaneously captures a collection of high-resolution biophysical and mechanical phenotypes of single cells at ultrahigh throughput (>10 000 cells per s).
View Article and Find Full Text PDFInternet-based Cognitive Therapy for Social Anxiety Disorder (iCT-SAD), a treatment that is normally supported by therapists, has been modified for delivery by trained coaches without mental health practitioner qualifications and has shown promising efficacy for patients in Hong Kong.
View Article and Find Full Text PDFProblem: The recovery of scandium (Sc), a critical rare earth element, is hampered by its dispersed geological occurrence and the economic and environmental drawbacks of conventional methods. While microbial extracellular polymeric substances (EPS) are promising biosorbents, their practical application is limited by insufficient target-specificity in complex matrices.
Solution: Inspired by bacterial adaptive responses, this study employed targeted scandium stress to modulate the composition and structure of EPS secreted by Methylobacterium extorquens, thereby enhancing the selective adsorption of scandium.
There is concern amongst the public, equestrians, animal welfare organisations, and horse-sport governing bodies regarding the welfare of performance horses, but equestrian culture appears slow to change. The present study seeks to increase our understanding of human factors underlying the persistence of welfare-compromising management and training practices within the performance horse world. Individual, semi-structured interviews focused on equestrians' attitudes were conducted with 22 equestrians from classical equestrian disciplines in the US, Canada, and the UK.
View Article and Find Full Text PDFBackground: This pioneering study examined the psychometric properties of workstyle related to work-related musculoskeletal symptoms (WRMS) among cleaners, a neglected workforce. Like many low-income, low-skilled workers, cleaners have unique workstyles. This research assessed the Workstyle-Short Form (WSF) to identify WRMS in various body parts among cleaners.
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