Publications by authors named "Drew Wright"

Objective: Psychological trauma can affect health and well-being across the lifespan but may be significantly impactful, with intergenerational consequences, during pregnancy. However, there appears to be no uniform agreement on the operationalization of psychological trauma in pregnancy. Such agreement is critical for the translation of research findings into clinical care.

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Background And Objectives: Free and open access to research data and findings promotes equity in access to healthcare knowledge and equity in patient care and treatment. To benefit the health care of the population studied, research findings must be accessible to clinicians, academics, and policymakers serving those populations. The aim of this study was to assess the extent of published Tanzanian neurosurgical data and its accessibility to those practicing within the country.

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Importance: Accessing forcibly displaced, pediatric populations for vaccination is challenging, and precise vaccination rates remain largely unknown.

Objective: To estimate vaccination coverage and identify factors associated with vaccination in forcibly displaced, pediatric populations.

Data Sources: Six databases were searched in November 2023-Ovid MEDLINE, Ovid EMBASE, PubMed, Scopus, Web of Science, and Cochrane-with no restrictions on language or publication dates.

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Background: Endoscopic sleeve gastroplasty (ESG) is an incisionless weight loss procedure that has been demonstrated to be safe and effective for the treatment of obesity; however, the efficacy of ESG for the treatment of comorbid type 2 diabetes mellitus (T2DM) and other components of metabolic syndrome (MetS) has been less well studied. We aimed to conduct a systematic review and meta-analysis of available literature to evaluate the outcomes of ESG on T2DM and MetS.

Methods: Bibliographic databases were systematically searched for studies assessing the outcomes of ESG on T2DM and MetS.

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Objective: Psychological trauma negatively impacts maternal and infant health during the perinatal period. A history of traumatic experiences related to previous pregnancies and births (termed pregnancy-specific psychological trauma or PSPT) increases the risk of a host of psychological disorders. It can impede women's/the pregnant individual's relationship with the healthcare system and their developing child.

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Objectives: The vast and complex nature of human genomic sequencing data presents challenges for effective analysis. This review aims to investigate the application of natural language processing (NLP) techniques, particularly large language models (LLMs) and transformer architectures, in deciphering genomic codes, focusing on tokenization, transformer models, and regulatory annotation prediction. The goal of this review is to assess data and model accessibility in the most recent literature, gaining a better understanding of the existing capabilities and constraints of these tools in processing genomic sequencing data.

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A history of psychologically traumatic experiences can impact health outcomes for pregnant people and their infants. The perception and prevalence of traumatic experiences during pregnancy may differ by geographical region. To better understand trends in how and what kinds of psychological trauma are assessed globally, we conducted a secondary analysis on a larger systematic review examining psychological trauma measurement in pregnancy.

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Objectives: The vast and complex nature of human genomic sequencing data presents challenges for effective analysis. This review aims to investigate the application of Natural Language Processing (NLP) techniques, particularly Large Language Models (LLMs) and transformer architectures, in deciphering genomic codes, focusing on tokenization, transformer models, and regulatory annotation prediction. This review aims to assess data and model accessibility in the most recent literature, gaining a better understanding of the existing capabilities and constraints of these tools in processing genomic sequencing data.

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Article Synopsis
  • * Critically ill patients often face dysphagia, a swallowing impairment that can lead to serious complications like aspiration pneumonia and even increased mortality if not properly managed.
  • * Regular assessments and interventions by trained specialists and ICU staff are essential to prevent and address dysphagia in these patients, highlighting the need for more research on effective management strategies.
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Background: Urogenital schistosomiasis caused by Schistosoma haematobium affects approximately 110 million people globally, with the majority of cases in low- and middle-income countries. Schistosome infections have been shown to impact the host immune system, gene expression, and microbiome composition. Studies have demonstrated variations in pathology between schistosome subspecies.

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Article Synopsis
  • EUS-FNA is a technique used for assessing pancreatic cysts, with an emphasis on determining the risk of pancreatitis, a common complication, to improve clinical decision-making.
  • A systematic review analyzed 64 studies involving over 8,000 patients, finding that the risk of pancreatitis from EUS-FNA is low at about 1.4% and typically mild.
  • Recent trends suggest that certain factors, like the type of needle used and the method of biopsy, might influence the risk, indicating a need for more research in this area.
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Article Synopsis
  • Women are significantly underrepresented in academic anesthesiology, with only 24% of authors being female and just 24% of guidelines being woman-led over the past five years.
  • A total of 51 clinical practice guidelines from top anesthesia journals were analyzed, revealing that many guidelines had few or no female authors, and the number of woman-led guidelines did not change during this period.
  • While woman-led guidelines featured a higher percentage of female authors and coauthors compared to man-led guidelines, there was no marked difference in the overall quality or ratings of the guidelines between genders, although a general improvement in guideline quality was noted over time.
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Background: Behavioral health (BH) comorbidities in hospice patients are widespread and impact important outcomes, including symptom burden, quality of life, and caregiver wellbeing. However, evidence-based BH interventions tailored for the hospice setting remain understudied.

Methods: We conducted a scoping review with the objective of mapping studies of interventions for BH comorbidities in the hospice setting.

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Torture survivors experience chronic, somatic pain that may be exacerbated by environmental, social, and structural factors that extend beyond immediate traumatic events and diagnoses. We conducted a systematic review of research describing the types and efficacy of treatments for chronic somatic pain in a global population of torture survivors. In this systematic review, we searched Ovid MEDLINE, Ovid EMBASE (1974 to present), and PubMed.

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There is growing literature supporting the efficacy of music interventions for a range of conditions, including anxiety, stress, and pain. Alongside this, research on neurobiological processes involved in the experience of music has illuminated potential mechanisms for music's role in mental health treatments. Music has the potential to act on the circuitry of the brain involved in the autonomic dysregulation associated with posttraumatic stress disorder (PTSD).

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Race-related variation in breast cancer incidence and mortality are well-documented in the United States. The effect of genetic ancestry on disparities in tumor genomics, risk factors, treatment, and outcomes of breast cancer is less understood. The Cancer Genome Atlas (TCGA) is a publicly available resource that has allowed for the recent emergence of genome analysis research seeking to characterize tumor DNA and protein expression by ancestry as well as the social construction of race and ethnicity.

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Background: The Weill Cornell Medicine, Samuel J. Wood Library's Systematic Review (SR) service began in 2011, with 2021 marking a decade of service. This paper will describe how the service policies have grown and will break down our service quantitatively over the past 11 years to examine SR timelines and trends.

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Spin is a way of reporting that distorts the true findings; we sought to investigate the prevalence of spin in systematic review abstracts on psoriasis treatments and whether study characteristics were associated with spin. We searched MEDLINE and Embase to obtain our sample. Screening and data extraction were performed in a masked duplicate fashion.

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Introduction: A patient-reported outcome (PRO) is any outcome reported directly by the patient, in contradistinction to a clinician-reported outcomes, which have dominated clinical research. This systematic review evaluates the ways in which PROs have been used in the interventional radiology literature.

Methods: Systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and was designed and conducted by a medical librarian.

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Objective: The optimal treatment algorithm for patients with degenerative lumbar spondylolisthesis has not been clarified. Part of the reason for this is that the natural history of degenerative spondylolisthesis (DS) has not been sufficiently studied. Comprehension of the natural history is essential for surgical decision making.

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Introduction: Anterior cervical discectomy and fusion (ACDF) is a common procedure to address cervical spine pathology. The most common grafts used are titanium, polyetheretherketone (PEEK), or structural allograft. Comparison of fusion rate is difficult due to non-standardized methods of assessment.

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Background: Spin-the misrepresentation of a study's actual results-has the potential to alter a clinician's interpretation of the study's findings and therefore could affect patient care. Studies have shown spin frequently occurs in abstracts of systematic reviews from a variety of other medical disorders and specialties.

Aims: Our primary aim was to evaluate whether the nine most severe types of spin occurred in systematic review abstracts' concerning diabetic neuropathy treatments.

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Objectives: Spin is a reporting practice in which study results are misrepresented by overestimating efficacy or underestimating harm. Prevalence of spin varies between clinical specialties, and estimates are based almost entirely on clinical trials. Little is known about spin in systematic reviews.

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