Clinical Equivalence of Clinifibre® and FiberWire® Ultra-High Molecular Weight Polyethylene Suture for Graft Preparation in Unilateral Anterior Cruciate Ligament Reconstruction: A Single-Blind Randomized Study.

Introduction Arthroscopic anterior cruciate ligament reconstruction (ACLR) is the gold standard for restoring rotational stability of the injured knee. The success of ACLR depends on surgical preparation and technique and is indicated by post-operative complications and functional outcomes. The study investigated the clinical equivalence of Clinifibre and FiberWire ultra-high molecular weight polyethylene (UHMWPE) sutures for graft preparation during unilateral primary ACLR.

The rare aggressive osteoblastoma in a two year old child in an unusual localization.

A rare bone tumor of 3rd metacarpal bone in a male child aged 2 years is being described. The patent presented with a gradually increasing, painful swelling over the dorsum of right hand which radiologically revealed an expansile, radioluscent mass, in 3rd metacarpal shaft with cortical destruction. The clinic-radiological differential diagnosis was aggressive cartilage tumor or an osteomyelitis.

Operative management of closed intra-articular fractures of distal end of humerus in adults.

This is a study of 60 patients with mean age of 30 years having intra-articular fracture of distal humerus of type C (AO classification). We treated these fractures by open reduction and internal fixation through transolecranon approach. Mean duration of operative time with that of injury was 10 days.

An evaluation of flexible intramedullary nail fixation in femoral shaft fractures in paediatric age group.

Sixty-two femoral shaft fractures in 60 patients treated by elastic intramedullary nailing with mean age of the patients being 9.2 years (range 5 years to 12 years) and average follow-up of 15 months (range 7 months to 60 months) are evaluated. Twenty-eight fractures were fixed with titanium elastic nail while 34 fractures were fixed with Enders nail.

Percutaneous fixation of displaced intra-articular calcaneal fracture.

Operative treatment modalities for calcaneal fracture are still controversial. The outcome of intra-articular calcaneal fracture is mainly influenced by the soft tissue and the subtalar joint. Percutaneous method of internal fixation has been attempted to avoid the problems.

Evaluation of pedicular screw fixation in dorsolumbar spinal injury.

Twenty-five patients with dorsolumbar spinal injury was treated by pedicular screw fixation along with direct or indirect decompression within 1 1/2 years period. Eighteen patients with incomplete neurodeficit had some amount of neurological recovery in terms of ASIA impairment scale but no neurological recovery was seen in 6 patients with complete neurological injury. Mean correction of kyphotic angle was 11.

Structure-function alteration of hemoglobin in arsenicosis patients: a probable pathway to exert toxicity.

Chronic arsenicosis, a major public health concern in India and Bangladesh, is mainly caused by ingestion of arsenic (As) contaminated ground water. Although this problem has been studied extensively, the mechanism of toxicity remains unknown. This paper investigates the process of trivalent arsenicals binding to hemoglobin (Hb) in chronic arsenicosis patients and consequent modification in the structure-function activity of Hb.

DNA hypermethylation of promoter of gene p53 and p16 in arsenic-exposed people with and without malignancy.

Chronic arsenic exposure is known to produce arsenicosis and cancer. To ascertain whether perturbation of methylation plays a role in such carcinogenesis, the degree of methylation of p53 and p16 gene in DNA obtained from blood samples of people chronically exposed to arsenic and skin cancer subjects was studied. Methylation-specific restriction endonuclease digestion followed by polymerase chain reaction (PCR) of gene p53 and bisulfite treatment followed by methylation-sensitive PCR of gene p16 have been carried out to analyze the methylation status of the samples studied.