Tunable Emission in Sb/Eu Codoped Rare-Earth-Based CsNaTbCl Double Perovskite and Its LED Applications.

CsNaTbCl lead-free dual perovskite (DP) has become one of the alternatives to CsPbBr perovskite quantum dots due to its advantages of nontoxicity, sharpness, and green luminescence. However, the synthesis method and luminescence performance of CsNaTbCl DPs need to be investigated. In this paper, a new synthesis method is used to dissolve metal chloride through water and ethanol, and Sb-Eu codoped CsNaTbCl lead-free double perovskite (DP) is prepared under atmospheric pressure and a low temperature (80 °C).

Transparent Ceramic@Sapphire Composites for High-Power Laser-Driven Lighting.

Although phosphor ceramics are promising candidates for high-power laser lighting applications, their performance is seriously restricted by luminance saturation effects. This study proposes a novel transparent ceramic@sapphire composite material design, fabricated via a straightforward high-temperature sintering process, which differs from the conventional approach of incorporating high-thermal-conductivity microcrystalline grains. This kind of composite can effectively avoid luminescence grain dilution, and deliver significantly enhanced thermal conductivity (36.

Glow-Worm-Inspired Fluorescent Self-Healing Actuators for Soft Robot and Reconfigurable Information Encryption.

Fluorescent actuators with light-emitting and shape-deformation properties are promising in bionics and soft robotics. However, current fluorescent actuators barely balance actuation performances with fluorescence properties, as they exhibit insufficient brightness, poor color-purity, low-stability, and few functional-integrations, limiting their applications in complex scenarios. Herein, inspired by glow-worms, a multifunctional fluorescent actuator by combining ultra-stable perovskite quantum dots with polyurethane and graphene oxide composites is reported, which integrates large deformation, high brightness, high color-purity, color-changing function and full-device self-healing function together.

Low-Threshold and Ultrastable Amplified Spontaneous Emission from CsPbBr@Glass via Glass Network Modulation.

Inorganic lead halide perovskite quantum dot (QD)-embedded glasses with exceptional optical properties and stability are promising optical gain media for laser applications, but their amplified spontaneous emission (ASE) typically occurs at high pumping thresholds. Here, we report a glass network modulation strategy for low-threshold ASE from CsPbBr@glass. By adding ZrO to enhance the glass network polymerization, high-quality and compact growth of QDs inside glass is promoted rather than uncontrolled self-crystallization.

Synergistic Integration of Halide Perovskite and Rare-Earth Ions toward Photonics.

Halide perovskites (HPs), emerging as a noteworthy class of semiconductors, hold great promise for an array of optoelectronic applications, including anti-counterfeiting, light-emitting diodes (LEDs), solar cells (SCs), and photodetectors, primarily due to their large absorption cross section, high fluorescence efficiency, tunable emission spectrum within the visible region, and high tolerance for lattice defects, as well as their adaptability for solution-based fabrication processes. Unlike luminescent HPs with band-edge emission, trivalent rare-earth (RE) ions typically emit low-energy light through intra-4f optical transitions, characterized by narrow emission spectra and long emission lifetimes. When fused, the cooperative interactions between HPs and REs endow the resulting binary composites not only with optoelectronic properties inherited from their parent materials but also introduce new attributes unattainable by either component alone.

Ultra-Narrowband Green-Emitting Transparent Composite Ceramics for Laser-Driven Display.

Laser-driven projection displays face a critical challenge in developing laser-excitable and high-performance narrowband green emitters. Herein, new AlO-LaMgAlO: Mn (AlO-LMA: Mn) transparent composite ceramics are reported via high-temperature vacuum sintering, which produces a high-color-purity (95.4%) green emission with full width at half maximum of 24 nm and superior thermal and moisture and laser irradiation stability.

Lanthanide Functionalized Carbon Quantum Dots for White Light Emission, pH Sensing, and Co (II) Detection.

Carbon quantum dots (CQDs) with fluorescence emission have been widely studied for versatile applications, but facile tunability of the spectral properties of CQDs by doping remains to be further explored. Herein, employing lanthanide ion Eu as a dopant and activator, a simple and efficient synthesis route for pure CQDs and Eu-CQDs was demonstrated using N, N-dimethylformamide, oleic acid, and oleylamine as precursors for carbon sources. In comparison, with the popular citric acid precursor, the as-prepared CQDs and Eu-CQDs exhibited an obviously smaller particle size (1.

Ultralow voltage-driven efficient and stable perovskite light-emitting diodes.

The poor operational stability of perovskite light-emitting diodes (PeLEDs) remains a major obstacle to their commercial application. Achieving high brightness and quantum efficiency at low driving voltages, thus effectively reducing heat accumulation, is key to enhancing the operational lifetime of PeLEDs. Here, we present a breakthrough, attaining a record-low driving voltage while maintaining high brightness and efficiency.

A Novel PiGF@Diamond Color Converter with a Record Thermal Conductivity for Laser-Driven Projection Display.

High-brightness laser lighting is confronted with crucial challenges in developing laser-excitable color converting materials with effective heat dissipation and super optical performance. Herein, a novel composite of phosphor-in-glass film on transparent diamond (PiGF@diamond) is designed and fabricated via a facile low-temperature co-sintering strategy. The as-prepared LaSiN:Ce (LSN:Ce) PiGF@diamond with well-retained optical properties of raw phosphor shows a record thermal conductivity of ≈599 W m K, which is about 60 times higher than that of currently well-used PiGF@sapphire (≈10 W m K).

Binary Host-induced Exciplex Enabled High Color-Rendering Index of 94 for Carbon Quantum Dot-Based White Light-Emitting Diodes.

White light-emitting diodes (WLEDs) with high color-rendering index (CRI, >90) are important for backlight displays and solid-state lighting applications. Although the well-developed colloidal quantum dots (QDs) based on heavy metals such as cadmium and lead are promising candidates for WLEDs, the low CRI still remains a significant limitation. In addition, the severe toxicity of heavy metals greatly limits their widespread use.

Crystal-Site Engineering of Novel NaKMg(PO)(BO):Eu Phosphors for Full-Spectrum Lighting.

The "cyan gap" is the bottleneck problem in violet-driven full-spectrum white-light-emitting diodes (wLEDs) in healthy lighting. Accordingly, we develop a novel broadband-blue-cyan emission NaKMg(PO)(BO):Eu (NKMPB:Eu) phosphor via crystal-site engineering. This phosphor is derived from the NaKMg(PO):Eu phosphor, which shows desired abundant cyan emissive components.

Gallic Acid Treats Hypertrophic Scar in Rabbit Ears via the TGF-β/Smad and TRPC3 Signaling Pathways.

Hypertrophic scars (HSs) develop due to excessive collagen deposition and abnormal fibroblast proliferation during wound healing, significantly impacting patient quality of life. Three dosages of GA ointments were administered to rabbit ear HS models to investigate the potential efficacy and mechanism of gallic acid (GA) on HS. Daily application of ointment was performed on the matrix group, the GA ointment groups, and the silicone gel group for 28 days.

Highly Bright and Stable Lead-Free Double Perovskite White Light-Emitting Diodes.

Lead-free double perovskites (DPs) are emerging highly stable emitters with efficient broadband self-trapped exciton (STE) photoluminescence (PL), but their low electroluminescent (EL) efficiency is a critical shortcoming. This work promotes the external quantum efficiency (EQE) and luminance of DP-based white light-emitting diode (wLED) with a normal device structure to 0.76% and 2793 cd m via two modifications: This work prevents the formation of adverse metallic silver, spatially confined STE, and lowers local site symmetry in Cs Na Ag In Bi Cl DP by terbium doping; and this work develops a guest-host strategy to improve film morphology, reduce defect density, and increase carrier mobility.

Grape seed proanthocyanidins regulate mitophagy of endothelial cells and promote wound healing in mice through p-JNK/FOXO3a/ROS signal pathway.

Skin wound healing is a dynamic and complex process that involves multiple physiological and cellular events. Grape seed proanthocyanidins (GSP) have strong anti-oxidation and elimination of oxygen free radicals, and have been shown to significantly promote wound healing, but the underlying mechanism remains unclear. Studies have indicated that reactive oxygen species (ROS) acts as an upstream signal to induce mitophagy, suggesting that GSP can regulate mitophagy through the signal pathway.

Ultra-Narrow-Bandwidth Deep-Red Electroluminescence Based on Green Plant-Derived Carbon Dots.

Deep-red light-emitting diodes (DR-LEDs, >660 nm) with high color-purity and narrow-bandwidth emission are promising for full-color displays and solid-state lighting applications. Currently, the DR-LEDs are mainly based on conventional emitters such as organic materials and heavy-metal based quantum dots (QDs) and perovskites. However, the organic materials always suffer from the complicated synthesis, inferior color purity with full-width at half-maximum (FWHM) more than 40 nm, and the QDs and perovskites still suffer from serious problems related to toxicity.

Seven-photon absorption from Na/Bi-alloyed CsAgInCl perovskites.

Nonlinear multi-phonon (2-7) absorption in the Na/Bi-alloyed CsAgInCl lead-free double perovskites with ∼100% photoluminescence quantum yield and superior stability is observed for the first time, which can be pumped by a femtosecond laser in a wide spectral range (800-2600 nm). First-principles calculations verify that the parity-forbidden transition from the valence band maximum and conduction band minimum (at the point) is not broken by Na/Bi doping, and strong optical band-to-band absorption occurs at the & points. Time-resolved emission spectra evidence that single-photon and multi-photon pumping leads to the same self-trapped exciton transition and high-order nonlinear absorption will not induce a remarkable thermal effect.

Traditional Chinese medicine for hypertrophic scars-A review of the therapeutic methods and potential effects.

Hypertrophic scar (HS) is a typical pathological response during skin injury, which can lead to pain, itching, and contracture in patients and even affect their physical and mental health. The complexity of the wound healing process leads to the formation of HS affected by many factors. Several treatments are available for HS, whereas some have more adverse reactions and can even cause new injuries with exacerbated scarring.

An Analysis of Life-Year Lost Due to COVID-19 - 34 Countries, December 2019-March 2021.

What Is Already Known About This Topic?: The coronavirus disease 2019 (COVID-19) pandemic has caused severe health consequences. Though most COVID-19 deaths occurred among very old people, their life-year loss might be very large because of their life expectancy at that age.

What Is Added By This Report?: This study quantified how many years of life were lost due to COVID-19 in 34 countries.

Effects of baloxavir and oseltamivir antiviral therapy on the transmission of seasonal influenza in China: A mathematical modeling analysis.

New antiviral influenza treatments can effectively alleviate illness while reducing viral shedding. However, how such effects can translate into lower population infections of seasonal influenza in China remains unknown. To shed light on the public health impacts of novel antiviral agents for influenza, we constructed a dynamic transmission model to simulate the seasonal influenza epidemics in China.

STAT1 Mediates the Transcription of CircIFI30 and Promotes the Progression of Triple-Negative Breast Cancer by Up-Regulating CDCA4.

Signal transducers and activators of transcription 1 (STAT1) is an important transcription factor that regulates the growth, survival, differentiation and apoptosis of various tumor cells. However, the biological roles of STAT1 and potential mechanisms in triple-negative breast cancer (TNBC) remain largely unknown. The expression levels of STAT1, CircIFI30, CDCA4, and epithelial-mesenchymal transition (EMT)-associated molecules (MM2, MMP9, E-cadherin, and N-cadherin) were evaluated using quantitative reverse transcription polymerase chain reaction (RT-qPCR).

Compact ultrabroadband light-emitting diodes based on lanthanide-doped lead-free double perovskites.

Impurity doping is an effective approach to tuning the optoelectronic performance of host materials by imparting extrinsic electronic channels. Herein, a family of lanthanide (Ln) ions was successfully incorporated into a Bi:CsAgInCl lead-free double-perovskite (DP) semiconductor, expanding the spectral range from visible (Vis) to near-infrared (NIR) and improving the photoluminescence quantum yield (PLQY). After multidoping with Nd, Yb, Er and Tm, Bi/Ln:CsAgInCl yielded an ultrabroadband continuous emission spectrum with a full width at half-maximum of ~365 nm originating from intrinsic self-trapped exciton recombination and abundant 4f-4f transitions of the Ln dopants.

A single-beam NIR laser-triggered full-color upconversion tuning of a Er/Tm:CsYbF@glass photothermal nanocomposite for optical security.

The development of advanced luminescent materials is highly desirable for addressing the rising threat of forgery. However, it is challenging to achieve stable full-color upconversion (UC) tuning in the same matrix upon a single-beam light excitation so as to ensure that authentic items are irreproducible. Herein, hexagonal Er/Tm:CsYbF nanocrystals (NCs) embedded inorganic glass an crystallization strategy is fabricated, which can emit blue, cyan, green, yellow, orange, red and near-infrared (NIR) UC emissions by simply modifying an incident 980 nm laser power.

Bright Electroluminescent White-Light-Emitting Diodes Based on Carbon Dots with Tunable Correlated Color Temperature Enabled by Aggregation.

Carbon dots (CDs) as one of the most promising carbon-based nanomaterials are inspiring extensive research in optoelectronic applications. White-light-emitting diodes (WLEDs) with tunable correlated color temperatures (CCTs) are crucial for applications in white lighting. However, the development of high-performance CDs-based electroluminescent WLEDs, especially those with adjustable CCTs, remains a challenge.

Ytterbium-Doped CsPbCl Quantum Cutters for Near-Infrared Light-Emitting Diodes.

Exploring highly efficient near-infrared (NIR) emitting materials is desirable for the advancement of next-generation smart NIR light sources. Different from most reported Cr-doped emitters with far-red emissions, Yb-activated phosphors are expected to yield pure NIR (∼1000 nm) light. Herein, a new hot-injection route using all metal-oleate salts to fabricate Yb-doped CsPbCl perovskite nanocrystals (PeNCs) is reported for the first time, which produce PeNC-sensitized Yb NIR emission with photoluminescence quantum yields (PLQYs) higher than 100%.

Economic evaluation of remdesivir for the treatment of severe COVID-19 patients in China under different scenarios.

Aims: The present study aimed to evaluate the cost-effectiveness of the 5-day remdesivir regimen compared with standard of care among severe COVID-19 patients in China, the evidence on which is essential to inform the necessity of securing access to remdesivir.

Methods: A dynamic transmission model that extended the susceptible-exposed-infected-recovered framework by incorporating asymptomatic, presymptomatic and waiting-to-be-diagnosed patients was constructed to conduct the cost-effectiveness analysis from the healthcare system perspective. To estimate epidemic parameters, the model was first calibrated to the observed epidemic curve in Wuhan from 23 January to 19 March 2020.