[Clinicopathological characteristics of well-differentiated papillary mesothelial tumor].

To investigate the clinicopathological characteristics of well-differentiated papillary mesothelial tumor (WDPMT). Sixteen cases of resected WDPMTs diagnosed at the Affiliated Hospital of Qingdao University, Qingdao, China from 2017 to 2024 were collected and the clinicopathological features were retrospectively analyzed. There were 7 males amd 9 females, with a mean age of 53.

Distinct prelimbic cortex ensembles encode response execution and inhibition.

Learning when to initiate or withhold actions is essential for survival, requiring the integration of past experiences with new information to adapt to changing environments. The prelimbic cortex (PL) plays a central role in this process, with a stable PL neuronal population (ensemble) recruited during operant reward learning to encode response execution. However, it is unknown how this established reward-learning ensemble adapts to changing reward contingencies, such as reward omission during extinction.

Isodeoxyelephantopin Promotes Cell Death in Triple-Negative Breast Cancer by Blocking STAT3 Phosphorylation and Enhancing the Effectiveness of Paclitaxel.

Triple-negative breast cancer (TNBC) is an aggressive and challenging subtype of breast cancer, presenting patients with a more complex treatment journey. This underscores the critical need for ongoing research and the development of effective therapies to enhance patient outcomes. Signal transducer and activator of transcription 3 (STAT3) is a crucial transcription factor that regulates various cellular processes, including proliferation, survival, and immune modulation.

Analysis of factors influencing the burden on family caregivers of disabled older adults in Guangzhou.

Objective: This study aims to investigate the current status of disability among older adults and analyze factors influencing the burden on their family caregivers in southern China.

Methods: A cross-sectional survey was conducted among 334 pairs of disabled older adults (≥65 years) and their primary family caregivers across three districts in Guangzhou. Face-to-face interviews using standardized questionnaires assessed disability levels via the "Long-term Care Disability Level Assessment" scale and caregiver burden via the Zarit Burden Interview (ZBI) scale.