miR-134 inhibits osteosarcoma cell invasion and metastasis through targeting MMP1 and MMP3 in vitro and in vivo.

miR-134 has been shown to be associated with angiogenesis and the progression of osteosarcoma. This study further assessed the effects of miR-134 expression on osteosarcoma cell migration, invasion, and metastasis in vitro and in a nude mouse xenograft model, exploring the underlying molecular events. Luciferase reporter assays revealed that miR-134 directly targets the 3'-UTRs of MMP1 and MMP3 to reduce their expression in osteosarcoma cells.

Robotics-assisted versus conventional manual approaches for total hip arthroplasty: A systematic review and meta-analysis of comparative studies.

Background: Several studies have compared robotics-assisted (RA) and conventional manual (CM) approaches for total hip arthroplasty (THA), but their results are controversial.

Methods: A literature search was conducted for controlled clinical trials (CCTs) comparing the clinical efficacy of the RA and CM approaches for THA and published between August 1998 and August 2018. The obtained data were analyzed using the statistical software Review Manager 5.

Clinical efficacy of OrthoPilot navigation system versus conventional manual total hip arthroplasty: A systematic review and meta-analysis.

Objective: This study was performed to compare the clinical efficacy between the OrthoPilot navigation system and conventional manual surgery in patients undergoing total hip arthroplasty.

Methods: The Embase, PubMed, CINAHL, and Cochrane databases were searched for clinical trials. The outcome measurements were the anteversion angle, inclination angle, and complications.

5-HTT, BMPR2, EDN1, ENG, KCNA5 gene polymorphisms and susceptibility to pulmonary arterial hypertension: A meta-analysis.

Background: The influence of 5-HTT, BMPR2, EDN1, ENG, KCNA5 genes polymorphisms on susceptibility of pulmonary arterial hypertension remains uncertain. This meta-analysis is conducted for further study.

Methods: We conducted a literature search on PubMed and ISI web of science databases for searching relevant articles until November 2017.

[Characteristics and the Relationship of Nitrogen and Phosphorus in Soil and Water of Different Land Use Types of a Small Watershed in the Three Gorges Reservoir Area].

Long-term field monitoring data was analyzed regarding the characteristics of nitrogen and phosphorus in the soil and shallow groundwater of different land use types in a typical small watershed of the Three Gorges Reservoir area. Furthermore, the relationships among soil nitrogen and phosphorus contents, concentrations of nitrogen and phosphorus in shallow groundwater, and slope surface runoff were analyzed. The results showed that the average contents of TN and NO-N in terrace soil were significantly higher than those in sloping upland soil (< 0.

[Influence of Spatial Pattern of Paddy Field on the Losses of Nitrogen and Phosphorus in Three Gorges Reservoir Area].

This paper used three plots of paddy field in Wangjiagou small catchment in Fuling District, Chongqing Municipality as a case study. Wangjiagou, located in Three Gorges Reservoir Area, provided a good case in terms of its closeness of surface runoff. The samples of individual rainfall of twelve times and process of two typical individual rainfalls on three plots of sloping paddy field were collected from 2014 to 2015.

[Nitrogen Losses Under the Action of Different Land Use Types of Small Catchment in Three Gorges Region].

As an independent water-collecting area, small catchment is the source of non-point source pollution in Three Gorges Region. Choosing 3 kinds of the most representative land-use types and using them to lay monitoring points of overland runoff within the small catchment of Wangjiagou in Fuling of Three Gorges Region, the author used the samples of surface runoff collected through the twelve natural rainfalls from May to December to analyze the feature of spatial-temporal change of Nitrogen's losses concentrations under the influence of different land use types and the hillslopes and small catchments composed by those land use types, revealing the relation between different land-use types and Nitrogen's losses of small catchments in Three Gorges Region. The result showed: the average losses concentration of TN showed the biggest difference for different land use types during the period of spring crops, and the average value of dry land was 1.

[Analysis of risk factors for anastomotic infectious complications following bowel resection for Crohn disease].

Objective: To investigate the risk factors for anastomotic infectious complications after bowel resection in patients with Crohn disease.

Methods: Clinical data of 124 patients with Crohn disease undergoing bowel resection between January 1990 and October 2012 were analyzed retrospectively. The risk factors were identified by χ(2) test and Logistic regression.

[Diagnostic value of Crohn disease activity indices in assessing postoperative recurrence].

Objective: To evaluate the diagnostic value of Crohn disease activity indices (CDAI) in assessing symptomatic recurrence following ileocolic resection for Crohn disease.

Methods: A total of 85 patients who underwent ileocolic resection between March 2003 and March 2010 were included. Clinical and endoscopic evaluation were performed within 12 months after operation.

[Value of quantitative examination via contrast-enhanced ultrasonography in evaluating the activity of Crohn disease at endoscopy].

Objective: To evaluate the predictive value of quantitative examination via contrast-enhanced ultrasonography on the activity of Crohn disease at endoscopy.

Methods: A total of 59 cases with Crohn disease in People's Hospital of Lishui City between January 2009 and December 2010 were collected prospectively and underwent both colonoscopy and contrast-enhanced ultrasonography. According to the Simple Endoscopic Score, Crohn disease was divided into inactive and active disease by colonoscopy.

[Soil soluble organic matter, microbial biomass, and enzyme activities in forest plantations in degraded red soil region of Jiangxi Province, China].

Taking the adjacent 18-year-old pure Pinus massoniana pure forest (I), P. massoniana, Liquidamber fomosana, and Schima superba mixed forest (II), S. superba pure forest (III), L.

Molecular dynamics simulation study on behaviors of liquid 1,2-dichloroethane under external electric fields.

Molecular dynamics simulation was carried out to study the behavior of liquid 1,2-dichloroethane molecules under external electric fields including direct current field, alternating current field and positive-half-period cosin field. The maximum applied field strength was 10(8) V/m, the maximum frequency of the alternating current field and that of the positive-half-period cosine field was 10(12) Hz. The simulation revealed that the field type and field strength act on the population of the molecular configuration.