Eur J Anaesthesiol
August 2025
Background: The combination of short- and long-acting local anaesthetics is traditionally associated with reduced block duration, though evidence remains inconsistent.
Objectives: To investigate the effects of a fixed or reduced dose of a long-acting local anaesthetic (ropivacaine) mixed with a short-acting agent (lidocaine-epinephrine) on duration of analgesia and sensory onset time in lateral infraclavicular blocks.
Design: Randomised, blinded, active-controlled superiority trial.
BMJ Open
July 2025
Introduction: Distal radius fractures account for one-fifth of all fractures in the active elderly population and may cause chronic pain, loss of hand function and reduced work productivity, imposing a significant socioeconomic burden. Most are initially treated with closed reduction and casting, but 30% subsequently require surgery due to insufficient realignment. The current approaches for analgesia for closed reduction are suboptimal.
View Article and Find Full Text PDFHematol Oncol
April 2022
Lymphomas of the nasal cavity and paranasal sinuses (NPS) are rare. Knowledge on sinonasal B-cell lymphoma (SNBCL) primarily comes from case series or single-center studies on small cohorts. We sought to determine the subtype distribution, clinical characteristics, disease behavior, and prognosis on a nationwide scale, with an emphasis on prognostic factors for the most common sinonasal lymphoma, primary sinonasal diffuse large B-cell lymphoma (PSDLBCL).
View Article and Find Full Text PDFBackground: Burkitt lymphoma rarely presents in head and neck (H&N) in Western countries.
Aims/objectives: We aimed to characterise clinicopathological features of H&N Burkitt lymphoma in Denmark representing a non-endemic region.
Material And Methods: Clinical records were reviewed for a nationwide cohort of patients diagnosed with H&N Burkitt lymphoma in Denmark between 1980 and 2018.
Background: HER2 aberrations in salivary gland carcinomas (SGC) as well as benefit of HER2 directed therapy have been reported in small studies. However, reliable estimates of the prevalence of HER2 positivity in SGC and its various histological subtypes are lacking.
Objective: To assess the prevalence of HER2 positivity in histological subtypes of salivary gland carcinomas (SGC).