Publications by authors named "Bruno Falissard"

Context And Objectives: Women with endometriosis report higher anxiety and depression levels compared with the general population. While numerous studies focused on chronic pain, few have investigated broader potential correlates of mental well-being in patients with endometriosis. This cross-sectional study aimed to highlight the factors associated with higher anxiety and depression symptoms in women with endometriosis.

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Aim: Depression and antidepressant drugs may both impact breast cancer incidence, potentially in opposite directions. The few epidemiological studies attempting to disentangle their effects have been inconclusive. We aimed to assess within the same prospective cohort the association between depression, antidepressant use, and breast cancer risk, while controlling for potential confounders.

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The assessment of acute non-procedural pain in term neonates in maternity wards is challenging due to the difficulty in selecting an appropriate scale and the time-consuming nature of the process. This can lead to inadequate neonatal pain management. To validate the EValuation ENfant DOuLeur (EVENDOL) pain scale for acute non-procedural pain in term neonates in maternity units by comparing it with the Echelle Douleur et Inconfort du Nouveau-né (EDIN) used as a reference.

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Background: Evidence regarding early interventions based on the Naturalistic Developmental Behavioral Interventions framework, such as the Early Start Denver Model (ESDM), suggests efficacy for autistic children. However, the effectiveness of ESDM across diverse cultural contexts remains under-researched.

Objective: To assess the effectiveness of ESDM compared with treatment as usual (TAU) on overall development in young children with autism spectrum disorder (ASD).

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French child and adolescent psychiatry (CAP) faces significant issues, primarily due to an overwhelming increase in demand and insufficient capacity. In response, the French society for child and adolescent psychiatry and allied professions (SFPEADA) initiated an action research project in June 2023 aimed at reimagining the future of CAP in France for the second quarter of the twenty-first century (2026-2050). Employing a holistic qualitative methodology that merges bottom-up and top-down approaches, the project progressed through four phases: interviews with informed individuals, consultations with trade unions or associations, synthesis of findings using thematic analysis and AI technologies, and public dissemination via a symposium at the Ministry of Health.

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Specific learning disorder with reading deficit (SLD-reading), or dyslexia, is one of the most common neurodevelopmental disorders. Intensive training with reading specialists is recommended, but delayed access to care is common. In this study, we tested an innovative user-friendly and accessible intervention, the medical device Mila-Learn, which is a video game based on cognitive and rhythmic training to improve phonological and reading ability.

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Background: Specific learning disorder (SLD) of reading skills impacts approximately 7% of children. Speech and reading therapy is currently the gold-standard intervention for improving children's reading abilities. However, intensive interventions are difficult to implement.

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Background: Prevention is important in the international primary care system. In adolescents, several prevention areas need to be addressed: sexual health, mental health, substance use and addiction, physical activity, screen use, and social relationships..

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Introduction: Autism spectrum disorder (ASD) is characterised by difficulty with social communication and restricted, repetitive patterns of behaviour. This study aimed to improve understanding of the ASD patient experience with the treatment (bumetanide) regarding the changes in core symptoms and to assess changes considered as meaningful. To achieve this, qualitative interviews were conducted with caregivers of patients in two phase 3 clinical trials (NCT03715153; NCT03715166) of a novel ASD treatment.

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Objectives: The COVID-19 pandemic had a huge impact on global mental health. Health care students, both as young people and regarding their student condition, were a more at-risk population. During the first and the third waves, two national surveys already found high levels of psychological distress (21 to 83% of severe psychological distress).

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Purpose: The recent worldwide health pandemic and related social distancing and restrictions negatively impacted adolescents' mental health, including depression, underscoring the need for comprehensive understanding beyond immediate impacts. We aimed to identify factors assessed during the first and second lockdowns that were associated with depression symptoms 2 years after restrictions easing.

Methods: This study included 1,946 adolescents, aged 15-18 years, involved in the French Epidémiologie et Conditions de Vie population-based cohort.

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New-onset psychiatric disorders are frequent after COVID-19. We aim to determine whether acute COVID-19 severity markers can predict post-COVID new-onset psychiatric disorders. We conducted an electronic health records (EHR) cohort study of patients hospitalized for COVID-19 and without any known history of psychiatric disorders.

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Purpose: Teenage pregnancy remains a significant global public health concern worldwide. However, it presents a complex phenomenon in developed countries, carrying potential short- and long-term consequences for both mothers and children.

Methods: This mixed method study used data from the French cross-sectional study "Portraits of adolescents", which included 6000 girls aged between 13 and 17 years.

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Factors influencing the implementation of parent-mediated intervention are insufficiently studied. This study examines for the first-time factors of implementation into clinical practice across the world of Pediatric Autism Communication Therapy, an internationally disseminated, evidence-based, parent-mediated therapy. From both the parents' and the professionals' perspectives, parents attitudes (e.

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School refusal (SR) is a form of school attendance problem (SAP) that requires specific mental health care. Despite improvements in the definition of SAPs, the course of SR is not well characterized. To explore three-year patterns of SR course in children, as reported by their parents, we deployed an anonymous web-based survey.

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No increased risk of postpartum major depression (PPMD) was reported in women conceiving through assisted reproductive technologies (ART). However, ART may be associated with a higher risk of parenting difficulties in women with PPMD. In 359 women with a PPMD admitted to a Mother-Baby Unit (MBU), ART-women (4.

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Symptomatic effects of mental disorders in parents could bias their reporting on their child's mental health. This study aimed to investigate the measurement invariance of the French version of the parental Strengths and Difficulties Questionnaire (SDQ) across parental mental health in a sample (N = 20,765) of parents of children aged 3 to 17 years in France. Confirmatory factor analysis (CFA) and Exploratory Structural Equation Modelling (ESEM) were used to evaluate the fit of three known alternative SDQ factor structures (five, three, or second-order factor structures).

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Objective: Short-term RCTs have demonstrated that MPH-treatment significantly reduces ADHD-symptoms, but is also associated with adverse events, including sleep problems. However, data on long-term effects of MPH on sleep remain limited.

Methods: We performed a 2-year naturalistic prospective pharmacovigilance multicentre study.

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Article Synopsis
  • The study aimed to investigate the long-term safety of methylphenidate (MPH), particularly regarding its impact on pubertal maturation and bone age.
  • Participants from a two-year observational study were compared across three groups: those on MPH, those not on MPH, and a control group without ADHD.
  • Results showed no differences in sexual maturation between medicated and unmedicated ADHD groups, and while there was slight bone maturation acceleration in the medicated group, their predicted adult height remained stable, indicating no long-term safety concerns with MPH.
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Background: Paternal mental health may have an impact on parenthood especially in case of maternal postpartum severe psychiatric illness.

Objective: The aim of this study was to search for an association between paternal psychiatric disorder and parents-baby separation after a maternal joint hospitalization for a severe postpartum psychiatric episode.

Participants And Settings: In an observational, naturalist and multicentric study, 787 fathers whose partner was hospitalized in a mother-baby unit were included.

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