Publications by authors named "Brady Ernst"

Introduction: Obesity is an increasingly prevalent comorbidity that confers greater risks of postoperative complications following total joint arthroplasty, underscoring the need for viable preoperative weight loss. The objective of this study was to compare the risk of 90-day adverse events in patients undergoing total knee arthroplasty (TKA) following bariatric surgery versus treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RA).

Methods: A retrospective review of a national research network from May 1, 2005, to February 12, 2025, identified patients undergoing TKA with bariatric surgery or GLP-1 RA prescriptions in the 18 months preceding their joint arthroplasty.

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Introduction: Psoriasis is an autoimmune inflammatory condition that often intersects with orthopaedic care due to its connection to psoriatic arthritis. However, not all psoriasis patients develop psoriatic arthritis. Psoriasis patients may undergo hip or knee arthroplasties for reasons unrelated to psoriasis.

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Background: Revision total hip arthroplasties (rTHA) are increasingly prevalent. Depending on the wear of implanted components the surgeon can replace the acetabular, femoral, or both components. The purpose of this study was to elucidate the differential outcomes and complications of rTHA by component(s) replaced.

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Purpose: Artistic gymnasts perform skills that involve repetitive flexion, hyperextension, and compressive loading, placing significant biomechanical stress on the lumbar spine. These demands contribute to the high prevalence of low back pain in this population. Despite its prevalence, there remains a need for targeted treatment strategies that address the sport-specific challenges faced by gymnasts.

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Purpose: Traditional bone-plug allografts in reconstruction of anterior cruciate ligament (ACL) tears require shaping of the bone plug by surgeons, yielding inconsistent results, greater costs, and increased operative time. We compare the load-to-failure between pre-shaped and surgeon-shaped Achilles allografts with calcaneal bone blocks to assess their use in ACL reconstruction.

Methods: Six pre-shaped Achilles allograft tendons with calcaneus bone grafts were compared to 6 surgeon-shaped allografts.

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Background: Reverse total shoulder arthroplasty (RTSA) has become increasingly popular in recent years, and this trend is expected to continue. However, differences in outcomes of RTSA for fractures compared with other indications are poorly understood. This study aimed to identify the compare the incidences of adverse events during RTSA to treat cuff tear arthropathy (CTA) versus RTSA to treat fractures, as well as identify risk factors for any adverse event.

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Background: Total joint arthroplasty (TJA) is a common orthopedic procedure.

Objective: The primary objective of this retrospective cohort study was to investigate 30-day postoperative complication rates following five major types of TJA (shoulder, elbow, hip, knee, ankle). Independent risk factors for adverse outcomes were also assessed.

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Background: Outpatient total knee arthroplasty (TKA) has quickly grown in popularity, largely driven by policy shifts and the recent coronavirus disease 2019 (COVID-19) pandemic. The aim of this study was to compare 30-day complications between outpatient TKA (oTKA) versus inpatient TKA (iTKA) before and after the COVID-19 pandemic to elucidate the effect of the pandemic on utilization and short-term outcomes.

Methods: Patients who underwent primary TKA between 2008 and 2021 were identified through Current Procedural Terminology codes in a national database.

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Purpose: This retrospective cohort study aims to compare short-term complication rates between patients receiving open reduction and internal fixation (ORIF) for associated versus elementary acetabular fractures, with a secondary objective of identifying independent risk factors for adverse outcomes.

Methods: The American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) database was queried using current procedural terminology (CPT) codes to identify patients that underwent ORIF for associated acetabular (CPT 27228) or elementary acetabular fractures (CPT 27226, 27227) from 2010 to 2021. Propensity score matching was employed to account for baseline differences and the short-term complication rates were compared between the cohorts.

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Introduction: The purpose of this retrospective cohort study was to assess differences in complication rates, early readmission rates, and reasons for readmission following TKA based on discharge destination. Secondarily, we aimed to identify independent risk factors for developing any adverse event (AAE) in the 30-day postoperative period.

Methods: The American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) was filtered using current procedural terminology (CPT) codes to identify patients undergoing TKA from 2015 to 2020.

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Background: Reflecting advancements in surgical techniques and postoperative care, total knee arthroplasty (TKA) is being performed increasingly as an outpatient procedure. This study aimed to report the frequency and timing of unplanned readmission after outpatient TKA with updated data, identify risk factors for readmission after outpatient TKA, and identify common causes for readmission after outpatient TKA with a much larger cohort compared to previous studies.

Methods: This study retrospectively analyzed data from 31,347 patients who underwent outpatient TKAs between 2012 and 2021.

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Article Synopsis
  • A study examined trends in technology-assisted total hip arthroplasty (TA-THA) from 2015 to 2020, comparing it to conventional THA based on data from the ACS-NSQIP database.
  • The analysis included over 219,000 conventional THA cases and about 2,258 TA-THA cases, revealing an increase in TA-THA usage until 2019, followed by a decline in 2020, and a yearly decrease in average hospital stay length until 2020.
  • TA-THA procedures had longer operative times and higher transfusion rates, but no significant difference in complication rates compared to conventional THA, highlighting its growing use without major short-term benefits
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Purpose: Provided that total hip arthroplasties (THA) are some of the most common surgical procedures performed, there is a necessity to understand all factors that contribute to risks of adverse outcomes postoperatively and to find solutions to avoid these events with preventive measures. This retrospective cohort study sought to assess differences in (1) postoperative complication rates, (2) readmission rates and reasons, and (3) demographic variables that contribute to readmissions based on discharge destination within the first 30 days after a THA.

Methods: Patients undergoing THA (27130) between 2015 and 2020 were extracted from the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database based on procedural codes.

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Article Synopsis
  • * A review of over 6,700 patients undergoing ORIF revealed that 1.9% experienced complications within 30 days, with surgical site infections (SSI) occurring in 0.77% of cases, while current smoking and older age were significant risk factors for adverse events.
  • * The research concluded that certain demographic factors, like being a current smoker or older, increase the likelihood of complications, whereas receiving treatment as an outpatient offered some protection against these adverse events.
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Background: Musculoskeletal conditions currently affect more than one-third of the US population and orthopedic procedures play a pivotal role in managing them. Like any invasive intervention, these carry a wide spectrum of risk, necessitating a comprehensive understanding of the associated morbidity and mortality. This study sought to provide a global perspective of the risks and complications associated with these procedures to establish an easy to understand risk stratification tool for both patients and providers.

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The purpose of this systematic review is to (i) compare post-operative activity levels after periacetabular osteotomy (PAO) versus PAO + HA (concomitant PAO and hip arthroscopy) using patient-reported outcomes that specifically assess activity and sports participation [Hip Disability and Osteoarthritis Outcome Score-Sport and Recreation subscale (HOOS-SR), University of California Los Angeles (UCLA) activity score, Hip Outcome Score-Sport-Specific Subscale (HOS-SSS)] and (ii) compare post-operative return to sport (RTS) data between PAO and PAO + HA groups. A systematic review of literature was conducted on 1 June 2023, utilizing PubMed, Cochrane and Embase (OVID). Articles were screened for inclusion using specific inclusion and exclusion criteria.

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Introduction: As the opioid epidemic enters its third decade, we reflect on how it has affected clinical practice within the orthopaedic community. Recent studies show prolonged opioid use after total knee arthroplasty (TKA) is associated with worse overall health outcomes. This study aims to elucidate trends in pain management after TKA over the past decade.

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Introduction: Open reduction and internal fixation (ORIF) is an established surgical procedure for distal humeral fractures; however, total elbow arthroplasty (TEA) has become an increasingly popular alternative for elderly patients with these injuries. Using a large sample of recent patient data, this study compares the rates of short-term complications between ORIF and TEA and evaluates complication risk factors.

Methods: Patients who underwent primary TEA or ORIF from 2012 to 2021 were identified by Current Procedural Terminology codes in the American College of Surgeons National Surgical Quality Improvement Program database.

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Background: Although elective procedures have life-changing potential, all surgeries come with an inherent risk of reoperation. There is a gap in knowledge investigating the risk of reoperation across orthopaedics. We aimed to identify the elective orthopaedic procedures with the highest rate of unplanned reoperation and the reasons for these procedures having such high reoperation rates.

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Introduction: Critical limitations of processed acellular nerve allograft (PNA) are linked to Schwann cell function. Side-to-side bridge grafting may enhance PNA neurotrophic potential.

Methods: Sprague-Dawley rats underwent tibial nerve transection and immediate repair with 20-mm PNA (n = 33) or isograft (ISO; n = 9) or 40-mm PNA (n = 33) or ISO (n = 9).

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Article Synopsis
  • The study investigates the role of cyclooxygenase (COX) in regulating cerebral blood flow (CBF) in young, healthy women compared to men.
  • Researchers found that women had higher baseline CBF, but both sexes showed similar vasodilatory responses to induced hypoxia and hypercapnia during the experiment.
  • COX was necessary for regulating baseline CBF and hypercapnic response equally in both sexes, but it wasn't essential for vasodilation during hypoxia.
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