IEEE Trans Biomed Circuits Syst
August 2025
This paper presents a field-programmable gate array (FPGA) based medical image processing framework using a hardware-software co-design approach for biomedical tasks such as Malaria and Pneumonia detection. The design is implemented on the AMD-Xilinx UltraScale+ MPSoC (ZCU104) FPGA, focusing on optimizing data movement between the Processing System (PS) and Programmable Logic (PL) through a customized high-level synthesis (HLS) process. Depth-wise convolution is employed to reduce computational complexity, while layer fusion is applied to optimize layer-wise execution, and custom cache is integrated to improve memory access efficiency.
View Article and Find Full Text PDFInt J Appl Basic Med Res
January 2025
Chondroid syringoma (CS) is a rare benign skin adnexal neoplasm. Its incidence is very low among all primary skin tumors. Diagnosing it clinically can be difficult as it closely resembles other benign salivary or adnexal neoplasms.
View Article and Find Full Text PDFPurpose: Bovine theileriosis, caused by Theileria annulata, presents a significant economic challenge to India's livestock industry. This study investigates the molecular epidemiology of T. annulata in bovine populations from Haryana, India, focusing on the genetic diversity of the Tams1 gene (785 bp).
View Article and Find Full Text PDFBackground: Acute spinal cord injury (ASCI) leads to severe neurological deficits with limited prognostic biomarkers. However, S100-beta (S100B), a calcium-binding protein, emerges as a beacon of hope, showing potential as a serological marker of ASCI severity and recovery, inspiring further research and exploration in this field.
Methods: This prospective case-control study included 26 patients with ASCI and 26 age- and sex-matched healthy controls.
Cutaneous squamous cell carcinoma (cSCC) is a non-melanoma (keratinocyte) skin cancer. cSCC can occur as primary cSCC, second primary cancer (SPC), or metastasis. Histopathology and genetic or molecular studies are used to differentiate SPC from metastasis.
View Article and Find Full Text PDFWe report a 37-year-old male patient who had nonbilious vomiting, no passage of flatus, and recurring abdominal pain. This patient had de novo intestinal myeloid sarcoma (MS), a rare and chameleonic presentation of acute leukemia of myeloid origin. The initial diagnostic evaluation suggested Koch's abdomen, and surgical excision of the bowel was performed with a clinical suspicion of Koch's or lymphoma.
View Article and Find Full Text PDFIntroduction: Globally, ticks rank second only to mosquitoes as vectors of deadly pathogens affecting humans and first in transmitting animal pathogens, presenting a significant challenge to human wellness and sustainability of livestock-based industries. Traditional tick control via chemical acaricides impacts on the environment and has led to the emergence of multi-acaricide-resistant tick populations. Use of immunoprophylactic, along with other components of integrated tick management, holds the potential to mitigate tick infestations in a sustainable manner.
View Article and Find Full Text PDFThrombocytopenia is common in the critical phase of dengue due to decreased production from the bone marrow and increased peripheral destruction of platelets. Platelet count improves with resolution of the disease. However, further evaluation is required if thrombocytopenia persists for a longer period following dengue infection.
View Article and Find Full Text PDFBackground: Technosoils in Inowrocław, central Poland, are impacted by human activities and exhibit high salinity (ECe up to 70 dS/m) due to a soda lime repository. These saline environments pose challenges to plant growth and soil health. However, they also offer an opportunity for the evolution of microorganisms adapted to such conditions, including plant growth-promoting rhizospheric (PGPR) bacteria.
View Article and Find Full Text PDFHaemoparasitic diseases constitute a significant constraint to economic livestock farming. Diagnostic techniques that are inexpensive, rapid, reliable, and precise are crucial for the management of diseases. In this context, PCR assays are very valuable yet expensive since the samples must be processed before being included in the PCR reaction.
View Article and Find Full Text PDFInfluenza viruses are known to cause severe respiratory infections in humans, often associated with significant morbidity and mortality rates. Virus replication relies on various host factors and pathways, which also determine the virus's infectious potential. Nonetheless, achieving a comprehensive understanding of how the virus interacts with host cellular components is essential for developing effective therapeutic strategies.
View Article and Find Full Text PDFEquine piroplasmosis caused by Theileria equi is a febrile, tick-borne disease of equids. However, there is limited literature about the genotyping of T. equi in India.
View Article and Find Full Text PDFFront Cell Infect Microbiol
December 2023
Drugs and chemotherapeutics have helped to manage devastating impacts of infectious diseases since the concept of 'magic bullet'. The World Health Organization estimates about 650,000 deaths due to respiratory diseases linked to seasonal influenza each year. Pandemic influenza, on the other hand, is the most feared health disaster and probably would have greater and immediate impact on humanity than climate change.
View Article and Find Full Text PDFIntroduction Subacromial impingement syndrome (SIS) is a common shoulder disorder characterized by pain and limited range of motion in the shoulder joint. It is frequently attributed to the compression or impingement of the rotator cuff tendons and bursa between the humeral head and the acromion process of the scapula during arm elevation. Subacromial impingement syndrome may arise as a result of the morphology of the acromion process, a bony protrusion at the top of the scapula that is important in the biomechanics of the shoulder joint.
View Article and Find Full Text PDFSince 2006, highly pathogenic avian influenza (HPAI) subtypes H5Nx have adversely affected poultry production in Nigeria. Successive waves of infections in the last two decades have raised concerns about the ability to contain infections by biosecurity alone, and evidence of recurrent outbreaks suggests a need for adoption of additional control measures such as vaccination. Although vaccination can be used to control virus spread and reduce the morbidity and mortality caused by HPAI, no country using vaccination alone as a control measure against HPAI has been able to eliminate or prevent re-infection.
View Article and Find Full Text PDFThe importance of the microbiome in the functioning of degraded lands in industrialised zones is significant. However, little is known about how environmental parameters affect microbial abundance, structure, diversity, and especially specific guilds involved in the nitrogen cycle in saline soils influenced by the soda industry. To address this knowledge gap, our research focused on assessing the microbiota in relation to soil properties and plant species composition across two transects representing different types of land use: saline wasteland and arable fields.
View Article and Find Full Text PDFThe emergence and re-emergence of viral diseases, which cause significant global mortality and morbidity, are the major concerns of this decade. Of these, current research is focused majorly on the etiological agent of the COVID-19 pandemic, SARS-CoV-2. Understanding the host response and metabolic changes during viral infection may provide better therapeutic targets for the proper management of pathophysiological conditions associated with SARS-CoV-2 infection.
View Article and Find Full Text PDFThe success of assisted reproduction relies on functional competence of frozen-thawed semen. Heat stress affects protein folding leading to aggregation of mis-folded proteins. Hence, a total of 384 (32 ejaculates/bull/season) ejaculates from six matured Gir bulls were used to evaluate physico-morphological parameters, the expression of HSPs (70 and 90) and fertility of frozen-thawed semen.
View Article and Find Full Text PDFThe present study was aimed at the identification, molecular characterization, and risk factor assessment of infection among sheep of Haryana province, north India. A total of 402 blood samples were collected from three different climatic zones of Haryana from March 2020 to September 2021. Light microscopy of blood smears revealed spp.
View Article and Find Full Text PDFMaedica (Bucur)
December 2022