Biochemical versatility and stress modulation: UGTs in the Fabaceae family.

The Fabaceae-specific review highlights the structural, functional, and phylogenetic diversity of UGTs, revealing clade-specific glycosylation mechanisms and novel sugar conjugations that contribute to legume adaptability. These insights offer promising avenues for metabolic engineering and stress-resilient crop development. UDP-glycosyltransferases (UGTs) are the biocatalysts modifying small molecules through glycosylation to enhance their solubility, stability, and bioactivity.

ABCB transporters: functionality extends to more than auxin transportation.

ABCs transport diverse compounds; with plant's most abundant ABCG and ABCB subfamilies. ABCBs are multi-functional transporter proteins having role in plant adaptation. ATP-binding cassette (ABC) proteins have been known for the transportation of various structurally diverse compounds in all kingdoms of life.

Comparative photocatalytic performance of iron nanoparticles biosynthesized from aqueous extracts of potato, potato peels, and leaves.

This study presents an eco-friendly, cost-effective approach for synthesizing highly efficient nanocatalysts with the help of organic waste. Iron nanoparticles (INPs) were synthesized from aqueous extracts of potato, potato peel, and potato leaf and were evaluated for their photocatalytic efficiency for the degradation of methylene blue dye. X-ray Diffraction (XRD) confirmed FeO nanoparticles cubic crystal structure with the smallest crystallite size (9.

Evaluation of Learning Approaches Among Physiotherapy Students in Haryana: A Cross-Sectional Study.

Introduction: Understanding students' learning approach, modifying teaching methods, curriculum and material accordingly is essential to deliver quality education. Knowing more about the learning approaches assists in upgrading the profession's quality for continuous professional development.

Methods: The cross-sectional study was carried out among physiotherapy students studying in physiotherapy colleges affiliated with the same university.

The Pain Descriptors Used by Individuals with Musculoskeletal Pain from Northern India.

Background: Chronic pain is a common health problem worldwide that results in significant costs to society and has negative impacts on the individuals with chronic pain. In order to study and treat pain, valid and reliable pain assessment is necessary, including assessment of pain quality. However, all of the most commonly used measures of pain quality were developed in Western countries.

Cenicriviroc, a CCR2/CCR5 antagonist, promotes the generation of type 1 regulatory T cells.

Cenicriviroc, a dual CCR2/CCR5 antagonist, initially developed as an anti-HIV drug, has shown promising results in nonalcoholic steatohepatitis phase 2 clinical trials. It inhibits the infiltration and activation of CCR2/CCR5 monocytes and macrophages to the site of liver injury, preventing liver fibrosis. However, the role of Cenicriviroc in the modulation of helper T cell differentiation and functions remains to be explored.

A transcriptome-wide identification of ATP-binding cassette (ABC) transporters revealed participation of ABCB subfamily in abiotic stress management of Glycyrrhiza glabra L.

Transcriptome-wide survey divulged a total of 181 ABC transporters in G. glabra which were phylogenetically classified into six subfamilies. Protein-Protein interactions revealed nine putative GgABCBs (-B6, -B14, -B15, -B25, -B26, -B31, -B40, -B42 &-B44) corresponding to five AtABCs orthologs (-B1, -B4, -B11, -B19, &-B21).

Enhancement in Bacterial Cellulolytic Enzyme Production Using Acid-Pretreated Banana Peel Waste: A Comparative Evaluation.

Banana peel waste is one of the major contributors in the issue raised from solid waste, however, it can be valorized effectively due to high content of cellulose and hemicellulose. Significant conversion of banana waste includes cellulolytic enzymes and bioenergy production. In the present study, bacterial cellulase was produced using raw banana peel and ripe banana peel under SSF.

Microbial cellulase production and stability investigations via graphene like carbon nanostructure derived from paddy straw.

Cellulases are among the most in-demand bioprocess enzymes, and the high cost of production, combined with their low enzymatic activity, is the main constraint, particularly in the biofuels industry. As a result, low-cost enzyme production modes with high activity and stability have emerged as the primary focus of research. Here, a method for producing a graphene like carbon nanostructure (GLCNs) has been investigated utilizing paddy straw (Ps), and its physicochemical characteristics have been examined using a variety of techniques including XRD, FT-IR, SEM and TEM.

Phytochemical Screening and Evaluation of Pesticidal Efficacy in the Oleoresins of Sims and Study.

Sims is an aromatic rhizomatous herb of family Zingiberaceae which is endemic to Peninsular India. This study first reports the phytochemical profile and pesticidal potential of oleoresins obtained from the aerial and rhizome parts of Sims. The oleoresins were prepared by the cold percolation method and were analyzed by a gas chromatography-mass spectrometry (GC-MS) method.

Thermophilic biohydrogen production strategy using agro industrial wastes: Current update, challenges, and sustainable solutions.

Continuously increasing wastes management issues and the high demand of fuels to fulfill the current societal requirements is not satisfactory. In addition, severe environmental pollution caused by generated wastes and the massive consumption of fossil fuels are the main causes of global warming. In this scenario, production of hydrogen from organic wastes is a potential and one of the most feasible alternatives to resolve these issues.

COVID-19 management landscape: A need for an affordable platform to manufacture safe and efficacious biotherapeutics and prophylactics for the developing countries.

To gain world-wide control over COVID-19 pandemic, it is necessary to have affordable and accessible vaccine and monoclonal antibody technologies across the globe. In comparison to the western countries, Asian and African countries have less percentage of vaccination done which warrants urgent attention. Global manufacturer production capacities, dependency on advanced nations for the supply of vaccines or the raw material, national economy, limited research facilities, and logistics could be the factors.

Anticholinergics May Carry Significant Cognitive and Gait Burden in Parkinson's Disease.

Background: Anticholinergic drugs are associated with significant cognitive and other adverse events in older adults, including those with Parkinson's disease (PD). Anticholinergic effects are considered lesser in younger individuals and the burden and outcomes in younger patients with PD are unknown.

Objectives: To determine the cumulative anticholinergic burden in a cohort of younger of patients with PD and to correlate the same with cognitive impairment and freezing of gait (FOG).

Role of glial fibrillary acidic protein as a biomarker in differentiating intracerebral haemorrhage from ischaemic stroke and stroke mimics: a meta-analysis.

Studies have suggested promising evidence that glial fibrillary acidic protein (GFAP) could be used as a blood biomarker to distinguish between ischaemic stroke (IS) and intracerebral haemorrhage (ICH) in acute stage. To determine the available evidence for GFAP as a blood biomarker for differentiating ICH from IS and stroke mimics using a meta-analysis approach. Search terms were used for literature search: ("STROKE" [Mesh] OR "BIOMARKER" [Title/Abstract] OR "GFAP" [Title/Abstract])] OR "SPECIFICITY" OR "SENSTIVITY" at various search engines like PubMed, Google scholar, Trip database, clinicaltrial.

Regional conduction velocity calculation from clinical multichannel electrograms in human atria.

Background: During atrial fibrillation, heterogeneities and anisotropies result in a chaotic propagation of the depolarization wavefront. The electrophysiological parameter called conduction velocity (CV) influences the propagation pattern over the atrium. We present a method that determines the regional CV for deformed catheter shapes, which result due to the catheter movement and changing wall contact.

MovAid- a novel device for advanced rehabilitation monitoring.

The present article introduces a new device "MovAid" which helps to measure and monitor rehabilitation. It has two main components- "MovAid device" and the "MovAid Smart Phone Application". The device connects wirelessly to the MovAid smart phone application via Bluetooth.

Removing ventricular far-field signals in intracardiac electrograms during stable atrial tachycardia using the periodic component analysis.

Background: Intracardiac electrograms are an indispensable part during diagnosis of supraventricular arrhythmias, but atrial activity (AA) can be obscured by ventricular far-fields (VFF). Concepts based on statistical independence like principal component analysis (PCA) cannot be applied for VFF removal during atrial tachycardia with stable conduction.

Methods: A database of realistic electrograms containing AA and VFF was generated.

Construction of intersubspecific molecular genetic map of lentil based on ISSR, RAPD and SSR markers.

Lentil (Lens culinaris ssp. culinaris), is a self-pollinating diploid (2n = 2x = 14), cool-season legume crop and is consumed worldwide as a rich source of protein (~24.0%), largely in vegetarian diets.

Electrocoagulation study for the removal of arsenic and chromium from aqueous solution.

This study was undertaken to investigate the removal of arsenic (As) and chromium (Cr) from aqueous solution using electrocoagulation (EC) technique. Batch EC studies were performed using iron electrodes to evaluate the influence of various experimental parameters on the removal of metal ions. The parameters were initial pH (pH(0)), electrolysis time (t), initial concentration (C(0)), electrode gap (g), stirring rate (r) and current density (j).