The detection of cannabinoids in breath after ingestion of cannabis-infused edibles.

The increase of Δ9-tetrahydrocannabinol (THC) in breath after cannabis inhalation has been well-documented in the forensic field, but the trends after ingestion of cannabis-infused edibles have not yet been investigated. In this study, participants ingested a cannabis-infused edible and provided breath samples before and at three timepoints after ingestion. Participants were assigned to one of two breath sampling devices.

Trends in Carrying Handguns Among Florida Adolescents: 2002-2022.

Objectives: This study explored changes in general handgun carrying, in-school carrying, favorable attitudes toward handgun carrying in school, and ease of handgun access among Florida adolescents.

Methods: Data were from even years between 2002 and 2022 from the Florida Youth Substance Abuse Survey, a repeated cross-sectional and representative survey of Florida middle and high school students (N = 701 649). Weighted logistic regression models estimated the prevalence of each outcome.

Impact of naturalistic cannabis use on lateral control and speed: A driving simulator study.

Objective: Cannabis has been shown to impair driving performance, but much of extant research has been conducted with relatively low concentration products, not reflective of the marketplace in states with legal adult recreational cannabis use. The study examined driving performance after cannabis use, inclusive of high concentration tetrahydrocannabinol (THC) products.

Methods: Participants ( = 118) completed three 20-minute simulated drives, with rural and urban segments.

Mode matters: exploring how modes of cannabis administration affect THC plasma concentrations and subjective effects.

As cannabis products become increasingly accessible and novel modes of administration like dabbing and vaping gain popularity, understanding how these modes impact use experiences and abuse liability is crucial. Existing studies primarily utilized laboratory settings with lower-potency research-grade cannabis, failing to capture common modes among individuals who use higher-potency legal market products. This study investigated how modes of administration impact plasma tetrahydrocannabinol (THC) concentrations and subjective effects using naturalistic administration of legal market products.

Sexual Violence Among a State Sample of High School Students: The Impact of Gender Identity and Sexual Orientation.

Sexual violence is a pervasive public health issue that has a direct and disproportionate impact on U.S. adolescents.

Commercial Cannabis Product Testing: Fidelity to Labels and Regulations.

Background: In Colorado, regulations for recreational and medical cannabis sales require Tetrahydrocannabinol (THC) concentration is printed on all products. Labeled THC concentrations can vary by +/-15% of what is in the product. Studies show THC concentrations recorded on product labels are not always reflective of the THC concentration in the cannabis product and there is evidence consumers make purchasing decisions based on label claims.

Racial disparities in concerns and experiences with police-involved shootings among Colorado adults.

Objective: To assess prevalence of concern and experiences with police-involved shootings among Colorado adults and differential impact on sociodemographic groups.

Methods: We analyzed a biennial state-representative online survey of Colorado adults, administered April-May 2023. Participants included the Ipsos KnowledgePanel of Colorado adults and additional opt-in respondents (n = 1,520).

Nicotine and cannabis vaping among early high school adolescents: Disparities of use across sociodemographic characteristics and associations with psychosocial factors.

This study examines whether adolescent nicotine and cannabis vaping types (i.e., nicotine-only, cannabis-only, and dual use) differ across sociodemographic and school characteristics (e.

Associations Between Age-for-Grade, Sex, and Interpersonal Violence Among U.S. High School Students.

The current study examines how atypical age-for-grade (i.e., being old- or young-for-grade) is associated with various types of interpersonal violence (e.

Methodological challenges and actionable recommendations in studying the health effects of high-concentration THC products.

In conducting a scoping review on the health effects of high-concentration cannabis products, we have uncovered pervasive methodological shortcomings within the cannabis literature. This paper begins by defining the 'causal effect' of interest for public health and delineating the desirable features of study design that can address crucial questions pertaining to public health and policy. We further delve into the methodological complexities inherent in studying the health effects of high-concentration cannabis products, describing challenges associated with the measurement of exposures and outcomes, confounding, selection bias, and the generalizability of findings.

Enhancing Methodological Approaches for Studying Health Effects of High-Concentration THC Products.

For public health protection, informed decision-making relies on having a robust foundation of evidence concerning risks and their prevention. Application of an evidence-based framework depends on the availability of pertinent, scientifically sound data generated by well-directed and valid research endeavors. In this essay, we address the current state of research in humans and the evidential base concerning high-concentration delta-9-tetrahydrocannabinol (delta-9-THC) products, which are readily available in the United States.

Dose Estimation Utility in a Population Pharmacokinetic Analysis of Inhaled Δ9-Tetrahydrocannabinol Cannabis Market Products in Occasional and Daily Users.

Background: Unusually high variability in blood Δ9-tetrahydrocannabinol (THC) concentrations have been observed in subjects inhaling similar cannabis products over similar time periods when consumption is ad libitum. This makes simple gravimetric dose estimation a poor predictor of THC exposure. Population pharmacokinetic analyses of blood THC concentration versus time data are routinely used to estimate pharmacokinetic parameters.

Acceptability and feasibility of video-based firearm safety education in a Colorado emergency department for caregivers of adolescents in firearm-owning households.

Background: Easy firearm access increases injury risk among adolescents. We evaluated the acceptability and feasibility of improving knowledge of a 3 min safe firearm storage education video in the paediatric emergency department.

Methods: We conducted a single-centre block trial in a large paediatric emergency department (August 2020-2022).

Improving Data-Driven Decision Making for Primary Prevention: Providing Data Interpretation Resources to Schools and Communities in Colorado.

Communities are increasingly interested in primary prevention efforts to reduce health inequities. However, few communities can access local data on social determinants of health and many do not have the skills or training to interpret data to inform decision making on appropriate strategies that impact social determinants of health. A population-based youth health survey administered to middle and high school students, such as exists in most states in the United States, can assess health behaviors and risk and protective factors.

Dose of Product or Product Concentration: A Comparison of Change in Heart Rate by THC Concentration for Participants Using Cannabis Daily and Occasionally.

Studies show that acute cannabis use significantly increases heart rate (HR) and mildly raises blood pressure in the minutes following smoked or inhaled use of cannabis. However, less is known about how the THC concentration of the product or an individual's frequency of use (i.e.

Accuracy and replicability of identifying eyelid tremor as an indicator of recent cannabis smoking.

Introduction: Cannabis intoxication may increase the risk of motor vehicle crashes. However, reliable methods of assessing cannabis intoxication are limited. The presence of eyelid tremors is among the signs of cannabis use identified under the Drug Evaluation and Classification Program of the International Association of Chiefs of Police.

Effects of acute cannabis inhalation on reaction time, decision-making, and memory using a tablet-based application.

Background: Acute cannabis use has been demonstrated to slow reaction time and affect decision-making and short-term memory. These effects may have utility in identifying impairment associated with recent use. However, these effects have not been widely investigated among individuals with a pattern of daily use, who may have acquired tolerance.