Dermatol Pract Concept
July 2025
Introduction: Speculatively, digital image post-processing (DIPP) enhances diagnostic accuracy in dermoscopy.
Objective: We aimed to investigate the advantages and limitations of DIPP, as well as its perceived reliability and safety.
Methods: In this study we investigated the perception and use of DIPP among members of the International Dermoscopy Society through a web-based survey with 17 questions focusing on: (i) demographics (sex, age, nationality, specialty, professional experience in dermoscopy), (ii) application of digital dermoscopy, (iii) imaging devices, (iv) DIPP software usage, (v) area of DIPP application (e.
J Am Acad Dermatol
July 2025
Background: There is lack of uniformity in reflectance confocal microscopy (RCM) terminology.
Objective: To establish expert consensus on a standardized set of RCM terms that describe non-melanocytic lesions (NMLs).
Methods: We invited RCM experts to participate in a Delphi-consensus study.
Artificial intelligence (AI) is already impacting the way we diagnose skin diseases. Although there are many new AI tools promoted to be helpful to dermatologists and primary care physicians, especially in the recognition of melanoma and nonmelanoma skin cancers, there is a major obstacle that the sponsoring companies must overcome before it is possible to integrate any of these innovative AI-enabled technologies into clinical practice. The regulatory process of the Food and Drug Administration (FDA) is demanding and requires proof of safety and effectiveness for each of these devices before the FDA gives their approval.
View Article and Find Full Text PDFJ Eur Acad Dermatol Venereol
September 2025
Background: When monitoring melanocytic neoplasms, the pattern of change may distinguish nevi from melanoma. Anticipating the growth dynamics of nevi based on their dermoscopic pattern is important to make this distinction.
Objectives: The primary aim was to examine the association between nevus dermoscopic pattern at baseline and diameter change during long-term monitoring.
Background: Differentiating melanoma (MM) from seborrheic keratosis (SK) containing a blue-white veil (BWV) remains challenging.
Objective: Identify dermoscopic features that can improve upon the differentiation between MMs and SKs exhibiting BWV.
Methods: Images from 110 MMs and 121 SKs containing BWV were aggregated, and 91 MMs and 62 SKs from this data set had complete agreement on the presence of BWV according to 3 expert dermoscopists.
J Am Acad Dermatol
October 2024
Lentigo Maligna (LM) arises on chronically-sun damaged skin and can have extensive subclinical spread, often in functionally and cosmetically challenging areas. This two-part continuing medical education (CME) series reviews LM. Part I reviews epidemiology, risk factors, clinical presentation, diagnostic tools, biopsy technique, and histopathology of LM.
View Article and Find Full Text PDFJ Am Acad Dermatol
October 2024
Lentigo maligna (LM) is an increasingly common subtype of melanoma, presenting as a slow-growing tan-brown macule or patch with irregular borders arising on chronically solar-damaged skin. This two-part continuing medical education (CME) series provides an overview of LM. Part I reviews LM's epidemiology, risk factors, and clinical presentation.
View Article and Find Full Text PDFIncorporation of dermoscopy and artificial intelligence (AI) is improving healthcare professionals' ability to diagnose melanoma earlier, but these algorithms often suffer from a "black box" issue, where decision-making processes are not transparent, limiting their utility for training healthcare providers. To address this, an automated approach for generating melanoma imaging biomarker cues (IBCs), which mimics the screening cues used by expert dermoscopists, was developed. This study created a one-minute learning environment where dermatologists adopted a sensory cue integration algorithm to combine a single IBC with a risk score built on many IBCs, then immediately tested their performance in differentiating melanoma from benign nevi.
View Article and Find Full Text PDFJ Am Acad Dermatol
December 2024
Importance: Somatic variants in the RAS/MAPK pathway genes are commonly associated with melanocytic nevi and melanoma, whereas germline variants in these genes are associated with RASopathies, syndromes involving multiple organs, including the skin. Nevi counts may be higher in some RASopathies, but studies on features observed through dermoscopy are limited.
Objective: To determine the distinguishing dermoscopic features of melanocytic nevi and how the RAS pathway influences them by comparing nevi in patients with cardiofaciocutaneous syndrome (CFC) and Costello syndrome (CS).
Dermatological conditions often present diagnostic challenges due to their diverse manifestations and overlapping clinical features. In such cases, dermoscopy, a non-invasive imaging technique, has emerged as a valuable tool to enhance diagnostic accuracy and guide clinicians in reaching an appropriate differential diagnosis. By visualizing subsurface skin structures and microvascular patterns, dermoscopy provides additional information that complements clinical examination, aiding in the recognition of specific dermatoses and the differentiation between benign and malignant skin lesions.
View Article and Find Full Text PDFJ Eur Acad Dermatol Venereol
January 2025
Background: A common terminology for diagnosis is critically important for clinical communication, education, research and artificial intelligence. Prevailing lexicons are limited in fully representing skin neoplasms.
Objectives: To achieve expert consensus on diagnostic terms for skin neoplasms and their hierarchical mapping.
Background: Pediatric melanoma presents with distinct clinical features compared to adult disease.
Objective: Characterize risk factors and negative outcomes in pediatric melanoma.
Methods: Multicenter retrospective study of patients under 20 years diagnosed with melanoma between January 1, 1995 and June 30, 2015 from 11 academic medical centers.
Clin Exp Dermatol
March 2024
Reflectance confocal microscopy (RCM) images skin lesions noninvasively at quasi-histological resolution. RCM has improved the diagnosis of skin neoplasms, and recently acquired billing codes in the USA. However, reading RCM images requires training, imposing a major barrier to its widespread adoption.
View Article and Find Full Text PDFBackground: Full-body skin examination (FSE) is a vital practice in the diagnosis of cutaneous malignancy. Precisely how FSE should be conducted with respect to concealed site inclusion remains poorly elucidated.
Objective: To establish the approach of Australian dermatologists to concealed site examination (CSE).
Dermatol Pract Concept
October 2023
Background: Lentigo maligna (LM) can mimic benign, flat, pigmented lesions and can be challenging to diagnose.
Objective: To describe a new dermatoscopic feature termed "perifollicular linear projections (PLP)" as a diagnostic criterion for LM on the face.
Methods: Retrospective study on reflectance confocal microscopy and dermatoscopy images of flat facial pigmented lesions originating from 2 databases.