Pediatric cardiothoracic surgeries are high-stakes, complex procedures, typically undergoing prior review at multidisciplinary conferences. This study evaluates practice patterns of conferences throughout the United States (US). Surveys were distributed to fellowship program directors or division directors in 124 US pediatric cardiology centers seeking information on conference logistics, fellow roles, quality improvement (QI), and satisfaction.
View Article and Find Full Text PDFBackground Chronic rhinosinusitis (CRS) significantly impacts patients' quality of life. Accurate diagnosis is crucial for effective management, with diagnostic nasal endoscopy (DNE) and computed tomography (CT) being primary tools. It significantly impacts patients' quality of life, causing symptoms like nasal congestion, facial pain, decreased sense of smell, and nasal discharge.
View Article and Find Full Text PDFJ Orthop Case Rep
July 2025
Introduction: Traditionally displaced supracondylar fractures of the humerus are treated by percutaneous pinning and above-elbow slab/cast support. Crossed pinning is commonly used as it provides better biomechanical stability than lateral pinning. The fracture is often associated with a high risk of complications such as neurovascular injury, pulselessness, and the development of swelling or compartment syndrome in acute scenarios.
View Article and Find Full Text PDFAppl Biochem Biotechnol
August 2025
This study investigated the potential of green-synthesized copper oxide nanoparticles (CuO NPs) to enhance biomass production and therapeutic metabolite yields in Alhagi maurorum, a medicinal plant of significant pharmaceutical value. CuO NPs were biosynthesized using A. maurorum leaf extract as a reducing and capping agent, with characterization confirmed via UV-Vis spectroscopy, FTIR, XRD, SEM, TEM, and zeta potential analysis.
View Article and Find Full Text PDFNanomaterials have revolutionized sensor technology by offering enhanced sensitivity, selectivity, and miniaturization capabilities. However, the commercialization of nanomaterial-based sensors remains challenging due to the complexities involved in bridging laboratory innovations to market-ready products. This review article explores the various marketing strategies that can facilitate the successful commercialization of nanomaterials for sensor applications.
View Article and Find Full Text PDFBiotechnol Appl Biochem
August 2025
This study evaluates the efficacy of garbage enzyme (GE) in bioremediation to reduce pollutants in sewage drains that discharge into the natural streams and rivers. Garbage enzyme is prepared with help of brown sugar, fruit, vegetable wastes, and water in the proportion 1:3:10 (by weight), which is then applied to the samples collected from various drainage sites in Jaunpur district, Uttar Pradesh, India. Different concentrations of GE (ranging from 0% to 20%) are mixed with sewage to assess pollution reduction.
View Article and Find Full Text PDFIntroduction: The study aims to assess the procedural outcomes and follow-up after transcatheter closure of ventricular septal defects (VSDs) in children utilizing the Konar-MF™ occluder (Lifetech Scientific, Shenzhen, PRC) device.
Materials And Methods: Clinical features, demographic characteristics, and follow-up findings of children undergoing percutaneous VSD device closure were retrospectively analyzed from the medical records.
Results: Fifty-seven patients underwent VSD closure using the Konar-MF occluder between January 2019 and April 2023.
The escalating threat of antimicrobial resistance has become a global health crisis. Therefore, there is a rising momentum in developing biomaterials with self-sanitizing capabilities and inherent antibacterial properties. Despite their promising antimicrobial properties, metal nanoparticles (MNPs) have several disadvantages, including increased toxicity as the particle size decreases, leading to oxidative stress and DNA damage that need consideration.
View Article and Find Full Text PDFBackground: Giant prolactinomas are rare; among them, the amyloidogenic variant, prolactinomas with extensive spherical amyloid deposits, are rare, with only 30 cases reported with recommendations of surgical management contrary to the routine prolactinoma's medical management.
Case Description: We report here a case of giant amyloidogenic prolactinoma in a 32-year-old male patient who had a very atypical presentation in terms of clinical, radiological, and pathological features and responded to dopamine agonist therapy like a normal prolactinoma.
Conclusion: Amyloidogenic giant prolactinomas are rare.
J Obstet Gynaecol India
April 2024
Introduction: The Maternal Mortality Rate (MMR) is one of the most important health indicators of a country. In India, MMR has decline from 130 to 113 per 100,000 live births between 2014 and 2018, however, there are wide disparities in utilization of maternal health services (MHS) among different states and across different socioeconomic groups within the states. Although the government is providing MHS through various health programs in India, there are several non medical factors leading to the underutilization of MHS services.
View Article and Find Full Text PDFCarbohydr Res
April 2024
To achieve better-repurposed motifs, saccharin has been merged with biocompatible sugar molecules via a 1,2,3-triazole linker, and ten novel 1,2,3-triazole-appended saccharin glycoconjugates were developed in good yield by utilizing modular CuAAC click as regioselective triazole forming tool. The docking study indicated that the resulting hybrid molecules have an overall substantial interaction with the CAXII macromolecule. Moreover, the galactose triazolyl saccharin analogue 3h has a binding energy of -8.
View Article and Find Full Text PDFWe report a first and interesting case of balloon-assisted deployment of a dislodged coronary stent. While performing a calcified left circumflex coronary artery (LCX) intervention, the drug-eluting coronary stent was dislodged in the osteoproximal segment of the calcified and tortuous LCX. The dislodged stent was rewired, progressively dilated with multiple balloons and, finally, a larger, balloon-mounted stent was pushed forward, positioned across the coronary lesion and deployed, resulting in distal thrombolysis in myocardial infarction (TIMI) III flow with good angiographic results.
View Article and Find Full Text PDFUnilateral absence of pulmonary artery (UAPA) can be either isolated or associated with other congenital cardiac defects. It is a rare congenital lesion with a diverse clinical presentation. We present a case of absent right pulmonary artery and large patent ductus arteriosus (PDA) with severe unilateral pulmonary hypertension.
View Article and Find Full Text PDFNanomaterials (Basel)
December 2023
Environ Sci Pollut Res Int
March 2025
Tea, the major beverage worldwide, is one of the oldest commercial commodities traded from ancient times. Apart from many of its advantages, including health, socio-economic, climatic, and agro-ecological values, FAO has recognized that the tea value chain covering its growth in the field, processing and marketing, and finally, the hot cup at the user's hand needs to be made sustainable during all these stages. Tea generates a lot of waste in different forms in different stages of its growth and processing, and these wastes, if not managed properly, may cause environmental pollution.
View Article and Find Full Text PDFBackground: Suspicious gallbladder wall thickening encountered during laparoscopic cholecystectomy poses challenges in its management. This study aims to address this problem by proposing a technique that involves laparoscopic transhepatic needle decompression and modified cystic plate cholecystectomy.
Methods: In this report, we describe the case of a 36-year-old female with symptomatic gallstone disease and ultrasound findings of a well-distended gallbladder with a uniform wall thickness.
Environ Sci Pollut Res Int
March 2024
Rapid urban population growth, the urbanization of poverty, and the proliferation of slums are being driven to a great extent by this dynamic form of globalization. Consequently, the multifaceted effects of globalization on the poor and low-income populations in the cities need to be better understood in this context, both at the individual level and within the community. Therefore, the present study was conducted to highlight the various determinants affecting the lives and enhancing the vulnerability of the dwellers of four slum settlements present in various areas of Jammu City, India.
View Article and Find Full Text PDFThe need for wearable bioelectronics continues to grow, and this technology might significantly alter the medical field. In order to diagnose and treat a patient, conventional medicine takes a "reactive" approach and waits for symptoms to appear first. Therefore, it is preferable to progress toward continuous non-invasive wearable biomonitoring, a preventative strategy that may assist individuals in diagnosing or treating illnesses at the earliest stages, sometimes before any outward symptoms have appeared.
View Article and Find Full Text PDFBioelectrochemical systems (BES) have emerged as a sustainable and highly promising technology that has garnered significant attention from researchers worldwide. These systems provide an efficient platform for the removal and recovery of valuable products from wastewater, with minimal or no net energy loss. Among the various types of BES, microbial fuel cells (MFCs) are a notable example, utilizing microbial biocatalytic activities to generate electrical energy through the degradation of organic matter.
View Article and Find Full Text PDFTo develop a better chemotherapeutically potential candidate for lung cancer treatment and cure with repurposed motifs, quinine has been linked with biocompatible CuAAC-inspired regioselective 1,2,3-triazole linker and a series of ten novel 1,2,3-triazolyl-9-quinine conjugates have been developed by utilizing click conjugation of glycosyl ether alkynes with 9-epi-9-azido-9-deoxy-quinine under standard click conditions. In parallel, the docking study indicated that the resulting conjugates have an overall appreciable interaction with ALK-5 macromolecules. Moreover, the mannose-triazolyl conjugate exhibited the highest binding interactions of -7.
View Article and Find Full Text PDFBiochem Biophys Res Commun
July 2023
Bacillus anthracis Ser/Thr protein kinase PrkC is necessary for phenotypic memory and spore germination, and the loss of PrkC-dependent phosphorylation events affect the spore development. During sporulation, Bacillus sp. can store 3-Phosphoglycerate (3-PGA) that will be required at the onset of germination when ATP will be necessary.
View Article and Find Full Text PDFOver the course of the last several decades, nanotechnology has garnered a growing amount of attention as a potentially valuable technology that has significantly impacted the food industry. Nanotechnology helps in enhancing the properties of materials and structures that are used in various fields such as agriculture, food, pharmacy, and so on. Applications of nanotechnology in the food market have included the encapsulation and distribution of materials to specific locations, the improvement of flavor, the introduction of antibacterial nanoparticles into food, the betterment of prolonged storage, the detection of pollutants, enhanced storage facilities, locating, identifying, as well as consumer awareness.
View Article and Find Full Text PDFBiosensors (Basel)
March 2023
Mycotoxins are naturally occurring toxic secondary metabolites produced by fungi in cereals and foodstuffs during the stages of cultivation and storage. Electrochemical biosensing has emerged as a rapid, efficient, and economical approach for the detection and quantification of mycotoxins in different sample media. An electrochemical biosensor consists of two main units, a recognition receptor and a signal transducer.
View Article and Find Full Text PDFMedEdPORTAL
January 2023
Introduction: Physicians need adequate physical exam skills. Unfortunately, interns have variable physical exam skills, and teaching is often limited to rounds, an inconsistent setting. Physical exam skills, particularly those involving auscultation, require practice.
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