Publications by authors named "Anchit Raj Singh"

Article Synopsis
  • A 55-year-old COVID-19 patient with no pre-existing conditions exhibited symptoms like fever, muscle pain, and headaches, along with low white and platelet blood cell counts at the time of diagnosis.
  • During treatment, the patient experienced a dramatic shift, developing high platelet and white blood cell counts later in the illness.
  • The case is notable for its unusual progression of hematological issues, featuring both low and then extremely high blood cell counts.
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Article Synopsis
  • The study aimed to explore the relationship between neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in predicting severe COVID-19 disease among Indian patients.
  • Out of 229 patients admitted, 191 were included for analysis, revealing that those with severe illness had significantly higher NLR (7.41) and PLR (204) levels compared to nonsevere patients (NLR 3.30; PLR 121).
  • ROC curve analysis indicated that NLR was more effective than PLR in predicting severe disease, with an AUC of 0.779, a cutoff of 4.1
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Background And Aims: Indian guidelines for anti-retroviral therapy (ART) are changing. More patients are now on protease-inhibitor (PI) based therapy. While the association of dyslipidemia with nucleoside reverse transcriptase (NRTI) based regimens is well-reported, the effect of Tenofovir (TDF) or PIs has not been studied in detail in India.

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Article Synopsis
  • - The study investigates D-dimer levels in COVID-19 patients, comparing those with diabetes to those without, given that diabetes is linked to worse outcomes in severe COVID-19 cases.
  • - A total of 98 patients were analyzed, revealing that those with diabetes had significantly higher peak D-dimer levels (1509 ng/mL) compared to non-diabetic patients (515 ng/mL).
  • - The findings suggest that COVID-19 patients with diabetes may face a greater risk of hypercoagulability and poorer prognosis, but further research is needed to understand the clinical implications of these results.
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