Structural studies on the interaction of CTAB with alginate: Possibility of surfactant therapy with chemo sensitization effect.

The present study reports the preparation of sodium alginate-cetyltrimethylammonium bromide (CTAB) nanoparticles (SANPs) through the interaction of a fixed concentration of alginate (0.2% w/v in water) with two different concentrations of CTAB i.e.

Alginate and Chitosan-Based Delivery Systems for Improving the Bioavailability and Therapeutic Efficacy of Curcumin.

One of the major challenges in harnessing the therapeutic benefits of curcumin (an active ingredient from turmeric) is its poor bioavailability due to its short biological half-life. In this regard, nanoformulations have shown tremendous hope for improving the pharmacokinetic and therapeutic behavior of curcumin by altering its biological stability and bioavailability. Biopolymers, especially alginate and chitosan, have received special attention as excipients to prepare nanoformulations of curcumin due to their abundant availability, biocompatibility, and amicability to form different types of self-assembled structures and ease of undergoing chemical modifications.