Visual and motor skills development in preterm and full-term infants: A protocol for longitudinal data collection.

Preterm birth, defined as birth before 37 weeks of gestation, affects approximately one in ten live-born infants globally. The risks and potential complications are more pronounced in infants born before 32 weeks, particularly those born before 28 weeks, necessitating specialized monitoring of developmental outcomes. Traditional developmental assessments often rely on performance-based observations, which can be subjective, and may not detect subtle or delayed difficulties that emerge later, such as in school-age children.

Tailoring Crohn's Disease Surveillance in Clinical Remission: New Insights from the Lewis Score.

Introduction: Optimal thresholds for Lewis score in the surveillance of patients with known Crohn's disease (CD) in clinical remission remain uncertain. The aim of this study was to evaluate predictive factors of clinical exacerbation in patients with small bowel inflammatory-type CD in clinical remission, focusing on the yield of the Lewis score.

Methods: This is a retrospective, unicentric cohort study including adult patients with known small bowel inflammatory-type, non-stricturing, and non-penetrating CD, in clinical remission, who were submitted to small bowel capsule endoscopy.

Propafenone-Induced Cholestatic Liver Injury: When Diagnosis Does Not Skip a Beat.

Introduction: Propafenone is a widely used class Ic antiarrhythmic drug that is mainly metabolised by the liver. Hepatotoxicity associated with propafenone is rare, with only a few clinical cases reported in the literature.

Case Presentation: We presented a case of propafenone-related hepatotoxicity, with cholestatic liver injury and development of jaundice and pruritus within 3 to 4 weeks of treatment initiation.

Unusual Location of a Rare Complication of Celiac Disease.

Introduction: Celiac disease has been associated with gastrointestinal malignancies, most commonly gastrointestinal lymphoma. Nevertheless, rarer malignancies have also been reported, such as small bowel adenocarcinoma, mainly located in the duodenum or jejunum.

Case Presentation: We report a case of a female patient with celiac disease with poor adherence to a gluten-free diet who presented with small bowel obstruction due to a primary ileal adenocarcinoma.

Participation and Activity Inventory for Children and Youth (PAI-CY): Translation and Cultural Adaptation to European Portuguese.

Visual skills have a significant impact on an infant's development and participation. In Portugal, although the public health system is organized to support citizens with visual impairment, it lacks translated and culturally adapted assessment tools. Knowing that a comprehensive assessment is crucial for early diagnosis and that it improves an infant's participation in daily life, the aim of the present article is to present the translation and cultural adaptation of the Participation and Activity Inventory for Children and Youth (0-2 years) into European Portuguese.

Granulomatous mastitis - Case report.

Introduction And Importance: Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic inflammatory breast disease with unclear etiology and no standardized treatment. It often presents as a painful breast mass that mimics breast cancer, necessitating thorough diagnostic evaluation.

Case Presentation: This report discusses a case of a 39-year-old pregnant woman with IGM associated with erythema nodosum, a poorly understood co-occurrence.

Assessing the Impact of a Structured Capsule Endoscopy Training Program Using a New Validated Assessment Tool.

Background And Aim: We aimed to develop and validate a simple capsule endoscopy (CE) training assessment tool, the Capsule Endoscopy Training Assessment (CETA), and prospectively use it to analyze the learning progression achieved by participants in our CE training program.

Methods: Over a 3-year period, all participants in our CE training program completed pre-training and post-training CETA, ranging between 0% and 100%, and encompassing theoretical questions and interpretation of segmented CE videos. We compared the mean differences in overall, theoretical, and practical pre-training and post-training CETA, and assessed the influence of previous endoscopic experience (upper gastrointestinal endoscopy [UGE], colonoscopy, device-assisted enteroscopy [DAE] and CE) using generalized linear models.

Recurrence rate after piecemeal endoscopic mucosal resection of <20 mm non-pedunculated colorectal lesions: should we worry about the risk?

Introduction: There is scarce data focused on recurrence neoplasia rate (RR) after piecemeal endoscopic mucosal resection (pEMR) of 10-19 mm non-pedunculated colorectal lesions (NPL). We aimed to analyze the RR after pEMR of 10-19 mm NPL, identify risk factors for its development and compare it with RR after pEMR of ≥ 20 mm NPL.

Methods: Retrospective cohort-study including all ≥10 mm NPL resected by pEMR in our center between 2018-2022 with an early repeat colonoscopy (ERC).

Gastric dysplasia in random biopsies: the influence of infection and alcohol consumption in the presence of a lesion.

Background: Gastric dysplasia in the absence of an endoscopically defined lesion is rare, usually either a false positive diagnosis or a previously unidentified precancerous lesion during esophagogastroduodenoscopy (EGD).

Aims: Evaluate factors associated with the presence of an endoscopically visible lesion during follow-up in patients with histologic diagnosis of gastric dysplasia in random biopsies.

Methods: Retrospective cohort study including patients referred to our institution for gastric dysplasia in random biopsies during Index EGD.

Prognostic impact of red blood cell distribution width in chronic heart failure patients with left ventricular dysfunction.

Aims: Red blood cell (RBC) distribution width (RDW) measures RBC variations in size. Higher RDW values have been associated with poor outcome in acute heart failure (HF). We aimed to assess the prognostic impact of the RDW in chronic HF.

Lung ultrasound and diuretic therapy in chronic heart failure: a randomised trial.

Background: Lung congestion is frequent in heart failure (HF) and is associated with symptoms and poor prognosis. Lung ultrasound (LUS) identification of B-lines may help refining congestion assessment on top of usual care. Three small trials comparing LUS-guided therapy to usual care in HF suggested that LUS-guided therapy could reduce urgent HF visits.

Predictors of clinical outcomes of hospitalized patients with Covid-19: focusing on pre-existing liver disease.

Chronic liver disease is associated with immune system dysfunction, which can lead to a greater risk of infections. Our goal was to assess the impact of chronic liver disease in Covid-19 outcome in hospitalized patients and to identify predictors of the infection's severity. A retrospective case-control study of adult patients hospitalized in Hospital da Senhora da Oliveira-Guimarães, between March 15th 2020 and March 15th 2021, was performed.

Serratia marcescens Endocarditis: A Case Report and Literature Review.

Serratia marcescens is a rarely implicated agent in endocarditis. We describe a case of a patient that underwent aortic and mitral valve replacement for Streptococcus agalactiae endocarditis. Four months later, he was readmitted with an ischemic stroke and fever.

Prognostic impact of neurohormonal modulation in very old patients with chronic heart failure.

Background: A gap in evidence exists concerning the survival-benefit of neurohormonal blockade in older patients with chronic heart failure (HF). The purpose of our study was to investigate the neurohormonal modulation therapy in older HF patients.

Methods: We retrospectively analysed data on chronic HF patients with systolic dysfunction from January 2012 to May 2018 at a central tertiary academic hospital in Porto, Portugal.

Pleural empyema due to : A rare yet severe complication of a previously undiagnosed cancer patient.

() has been increasingly recognized as an emerging opportunistic pathogen causing invasive fungal infection, mainly in immunosuppressed patients. We report the case of a previously undiagnosed lung cancer patient with a pleural empyema due to .

Acquired Hemophilia A associated with bullous pemphigoid: A rare combination.

Acquired Hemophilia A (AHA) is a rare autoimmune disorder, caused by the development of circulating autoantibodies against coagulation factor VIII (FVIII). AHA is associated with bullous pemphigoid in 2% of patients. We report a case of a 74-year-old man admitted with anemia and a tense subcutaneous and muscular hematoma in the right thigh.

Non-ketotic hemichorea-hemiballismus presenting as generalised tonic-clonic convulsive state in uncontrolled diabetes.

We report the case of a 70-year-old diabetic woman who presented to the emergency department with multiple seizure episodes and coma, prompting the need for sedation and mechanical ventilation. She was transferred to our institution for neurosurgical evaluation as the initial CT scan identified hyperdense lesions in the left basal ganglia, interpreted as acute intracranial haemorrhage. On admission, laboratory tests were mostly normal except for blood glucose of 413 mg/dL.

Jejunal intussusceptions due to metastatic malignant melanoma: a case report.

Intussusception is an infrequent cause of mechanical bowel obstruction in adults and surgical resection is warranted in most cases. Small bowel is a common site of recurrence from cutaneous melanoma but early diagnosis is still a challenge. Acute peritonitis, haemorrhage and obstruction are known clinical presentations.

Asymptomatic Hyperinsulinaemic Hypoglycaemia.

Unlabelled: Hypoglycaemia is rare in apparently well patients without drug-treated diabetes mellitus and warrants evaluation and management when Whipple's triad is present. Even in the absence of Whipple's triad, when repeatedly low values of plasma glucose are documented, the presence of endogenous hyperinsulinism should be investigated. The authors describe a case of endogenous hypoglycaemic hyperinsulinism, its diagnosis and treatment and the challenges of determining its aetiology.