Res Vet Sci
September 2025
Human listeriosis is a severe food-borne illness, with fatality rates ranging from 20 to 30 %. In Brazil, despite being an underdiagnosed and underreported disease, the presence of the microorganism in food has been the subject of important studies. However, its occurrence in slaughterhouse environments has received little attention in recent years.
View Article and Find Full Text PDFBackground: The efficacy of clear aligner treatment (CAT) in space closure following premolar extraction (SCaPE) and its resistance to unwanted tooth movement remain uncertain. This systematic review aims to evaluate the efficacy, predictability, and resistance to unwanted tooth movement by CAT for SCaPE.
Methods: Pre-post studies, randomized, and non-randomized clinical trials were included.
Arch Endocrinol Metab
August 2025
Objective: To identify factors potentially associated with radioiodine-refractory disease among patients treated for differentiated thyroid carcinoma at a referral center in Northeastern Brazil.
Methods: A total of 554 medical records of patients with differentiated thyroid carcinoma treated between January 2010 and August 2024 were evaluated. Radioiodine-refractory disease tumors were detected in 44 (7.
Statement Of Problem: A consensus regarding the indications and performance of removable partial denture (RPD) clasps manufactured with thermoplastic polymers is lacking.
Purpose: The purpose of this systematic review and meta-analysis was to evaluate the published literature on the retention forces of RPD clasps made of polymers and compare them with those made of cobalt chromium (Co-Cr).
Material And Methods: A comprehensive search of studies published up to January 2024 was performed in PubMed/MEDLINE, Web of Science, and Cochrane Library databases according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement criteria and was registered in the Open Science Framework (https://osf.
Objective: to understand the perception of teachers from the municipal education network regarding the inclusion of children with special healthcare needs in the school context.
Method: qualitative research carried out through semi-structured interviews with 22 teachers from nine public schools in southern Brazil between November and December 2023. The selection strategy was conducted by educational clusters, schools were selected by probabilistic sampling and participants by convenience.
Background: The Framingham risk score and Pooled Cohort Equations (PCE) have never been recalibrated for the Brazilian population. In contrast, the Globorisk-LAC score was recently derived using a methodology analogous to the PCE and has been recalibrated for Latin American countries.
Objectives: To describe the agreement between the Framingham, PCE, and Globorisk-LAC scores in estimating the 10-year cardiovascular risk in the Brazilian population.
Background: Eating disorders (EDs) are severe mental illnesses with high rates of mortality, morbidity, and reduced quality of life. Their onset occurs during adolescence and early adulthood, coinciding with the critical transition from pediatric to adult care. To address the lack of guidelines to support ED transitions in Canada, this study developed evidence-based guideline recommendations.
View Article and Find Full Text PDFInt J Med Inform
July 2025
Background: The exponential growth of digitized medical data has created significant challenges for healthcare professionals, as medical documentation transitions from simple text records to complex, multi-dimensional data structures. Natural Language Processing (NLP), particularly Named Entity Recognition (NER), has emerged as a crucial tool for extracting and categorizing critical information from clinical texts. The development of transformer-based models like BERT and the ability to fine-tune pre-trained AI models have revolutionized the field, offering unprecedented opportunities to enhance the efficient and precise interpretation of medical data across diverse languages and healthcare contexts.
View Article and Find Full Text PDFIntroduction: This study investigated microperimetry-derived retinal sensitivity and optical coherence tomography (OCT)-based macular morphologic data in eyes with early and intermediate age-related macular degeneration (AMD). The respective metrics were compared between macular subfields and their associations were determined. Detailed knowledge of functional associations with morphology is an asset to future therapeutic trial design.
View Article and Find Full Text PDFNew psychoactive substances (NPSs) are emerging narcotics or psychotropics that pose a public health risk. The most commonly reported NPSs are synthetic cannabinoids and synthetic cathinones. Synthetic cannabinoids mimic the effects of Δ9-tetrahydrocannabinol (Δ9-THC), often with greater potency, while synthetic cathinones act as stimulants, frequently serving as cheaper alternatives to amphetamines, 3,4-methylenedioxymethamphetamine (MDMA) and cocaine.
View Article and Find Full Text PDFDiabetol Metab Syndr
July 2025
Cognitive decline is a significant complication of type 1 diabetes (T1D) that substantially affects patients' quality of life. Although previous studies suggest that Neutral Protamine Hagedorn (NPH) insulin may mitigate certain effects of streptozotocin-induced type 1 diabetes (T1D), the impact of NPH on diabetes-related cognitive decline remains unclear. This study evaluated the efficacy of NPH insulin in attenuating spatial, short-term, and long-term memory deficits in T1D rats, assessing their progression at 10, 20, and 30 days following diabetes induction and treatment initiation.
View Article and Find Full Text PDFJ Evid Based Soc Work (2019)
July 2025
Purpose: The current review sought to characterize evaluation strategies relevant to evidence-based parenting programs (EBPP) implementation in real-world settings, specifically addressing programs' implementation characteristics, outcomes and economic evaluations under a pluralistic approach.
Materials And Method: We conducted a narrative review of peer-reviewed literature completing the scale for the assessment of narrative review articles (SANRA) and following the preferred format Introduction, Method, Results and Discussion (IMRD) to outweigh appraisals of non-systematic procedures. We searched Web of Science, PsycARTICLES, PsycINFO, Education Source Ultimate, Psychology and Behavioral Sciences Collection, and Sociology Source Ultimate for keywords related to the concepts of parenting program, evaluation, implementation, pluralistic approach, and community-based services.
Polymeric nanofibers have significantly contributed to biotechnological advancements due to their high surface area and porosity, which support the immobilization of bioactive compounds and microorganisms. These features make them valuable in diverse sectors such as food packaging and enrichment, environmental remediation, and biomedical applications. Conventional electrospinning (CE) is a well-established method for producing nanofibers; however, it presents limitations including low productivity, capillary clogging, and long processing times, which restrict its scalability.
View Article and Find Full Text PDFObjective: To estimate the association between exposure to particulate matter with less than 10u of aerodynamic diameter (PM10) and hospital admissions due to acute respiratory diseases in children.
Methods: This is an ecological time series study with data on hospitalizations for respiratory diseases in children living in the conurbated cities of Taubaté, Tremembé, and Pindamonhangaba located in the Vale do Paraíba in São Paulo. Hospital admission data refer to the period between January 1, 2016 and December 31, 2019.
Ophthalmol Ther
August 2025
Introduction: This study aimed to investigate the utility of microaneurysm (MA) counting as a tool for characterizing the hyperperfusion stage of nonproliferative diabetic retinopathy (NPDR) and to examine the hypothesis that MAs can serve as a surrogate biomarker for the presence of intraretinal microvascular abnormalities (IRMAs).
Methods: Forty-nine (n = 49) eyes with type 2 diabetes mellitus with NPDR were included in this analysis: 12 with Early Treatment Diabetic Retinopathy Study (ETDRS) levels 43 and 37 with levels 47-53. Automated MA detection was performed using the RetmarkerDR software (Retmarker SA, Meteda Group, Italy), alongside manual detection, both done in the central retina (field 2).
Rev Esp Cardiol (Engl Ed)
June 2025
CD109 is a glycosylphosphatidylinositol-anchored protein. In addition to regulating transforming growth factor β (TGF-β) network signaling, CD109 is also a protease inhibitor. Protease cleavage of its bait region triggers a conformational change releasing the major fragment from the cell surface, exposing a reactive thioester that can conjugate proteases.
View Article and Find Full Text PDFThe objective of this study was to analyze the lack of access to health services in the context of the COVID-19 pandemic by women, intersecting skin color, income, and schooling. This is a population-based cross-sectional study with 1,107 women aged 18 years or older living in Vitória/ES. The study had as its dependent variable the lack of access to medical consultations and as independent variables skin color, income, education, age, health insurance and jeopardy index.
View Article and Find Full Text PDFBackground: Aortic valve stenosis remains the most prevalent valvular pathology in Western countries. Rapid deployment bioprosthesis (RD) has emerged as a promising alternative to conventional valves for surgical aortic valve replacement (SAVR), particularly in elderly and high-risk patients. This study reports the short- and long-term outcomes of RD in patients with isolated aortic stenosis.
View Article and Find Full Text PDFThis study evaluated the effects of vascular photobiomodulation (VPBM) on pain intensity, edema, and facial temperature variation in patients undergoing alveolar bone grafting (ABG) surgery. A total of 42 patients with cleft lip and palate (aged 9-25 years) scheduled for ABG using iliac crest bone were randomly assigned in equal numbers (14 per group) to one of three groups: control (ABG only), test (ABG + VPBM), and placebo (ABG + simulated VPBM). Iliac and facial pain and edema were clinically evaluated 24 h post-surgery, along with thermographic facial analysis.
View Article and Find Full Text PDFBackground: As Parkinson's disease (PD) progresses, patients experience difficulties with gait and balance, requiring assistive devices to ensure fall prevention and safety. Despite the advantages provided by these aids, many people with PD do not adhere to their use.
Objective: This study aims to explore the barriers to using assistive devices among people with PD and identify strategies to improve their adherence.
Front Microbiol
April 2025
The Mycobacterium genus remains highly relevant today due to the rising incidence of tuberculosis and opportunistic infections caused by environmental mycobacteria. While much is known about , and , studies focusing on environmental mycobacteria remain limited. These microorganisms are globally distributed and have been identified in diverse biomes, including the Atlantic Forest.
View Article and Find Full Text PDFSince their discovery, carbon dots (CDs) have been extensively studied for their potential in diverse applications owing to their unique properties such as high biocompatibility, excellent water solubility, low toxicity, minimal photobleaching, and exceptional chemical versatility. These characteristics position CDs as promising candidates for overcoming the limitations of various molecular compounds. This review provides a comprehensive analysis of the synergistic effects arising from the integration of CDs and phthalocyanines (Pcs) to form hybrids with distinct photophysical and photochemical properties.
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