Publications by authors named "Amr H Hashem"

Alternaria solani leaf spot disease (ASLS) poses a serious threat to global crop production, including peppers, resulting in notable economic losses. Bio-nanotechnology offers promising solutions for combating plant pathogens by promoting plant defenses and inhibiting pathogen growth. This study explores the effectiveness of copper oxide nanoparticles (CNPs) and copper phosphite (MAXIFOS CU®) in controlling A.

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Natural plant extracts provide a cost-effective and eco-friendly option for the synthesis of bimetallic nanoparticles, as opposed to traditional chemical or physical methods. This research involved the bio-fabrication of silver-titanium dioxide bimetallic nanoparticles (Ag-TiO BNPs) utilizing the leaf extract of Pluchea indica. The Ag-TiO BNPs underwent characterization through UV-vis spectroscopy, FTIR, TEM, XRD, and DLS techniques.

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Microorganisms are promising, cost-effective, and sustainable producers of bioproducts, including polyhydroxybutyrate (PHB), a biodegradable polymer that offers an eco-friendly alternative to synthetic plastics. This study investigates PHB production using the newly isolated Vreelandella piezotolerans with orange peel waste as the substrate. Notably, this is the first research to optimize PHA production with V.

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Endophytic fungi offer a sustainable and eco-friendly alternative to synthetic insecticides, providing targeted pest control with reduced environmental toxicity and lower risk of resistance development. In this study, four endophytic fungi were isolated from Olea europaea and their ethyl acetate extracts' larvicidal efficacy of Culex pipiens. Boxplot distributions revealed a positive correlation between metabolite concentration and larval mortality, with higher doses inducing greater lethality.

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Fungal extracts have garnered significant interest in recent years for their diverse applications in pharmaceutical field. This research focused on isolating fungi from the gut of Scarus ghobban for the first time and evaluate their biological activities Aspergillus niger was successfully isolated and identified using morphological and molecular techniques. Gas chromatography-mass spectrometry (GC-MS) analysis of the ethyl acetate extract (EA) of A.

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Aromatic plants produce essential oils (EOs) with diverse phytochemicals and biological applications. This study investigated three eco-friendly nanoemulsions of Lemon peel (LPO), Turmeric (TO), and Black seed (BSO) oils loaded into nanochitosan (NCh) for their antifungal activity against resistant fungal strains. Phytochemical analysis identified oxygenated/non-oxygenated hydrocarbons and saturated/unsaturated fatty acids in the EOs.

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The unregulated administration of currently available antimicrobial agents resulted in overspreading of resistant microbial phenotypes. In this study, Mucor racemosus was used for biosynthesis of zinc oxide nanoparticles (ZnO NPs) through fungi-based ecofriendly approach. The biosynthesized of ZnO NPs was initially considered based on analytical practices including UV-vis spectroscopy and transmission electron microscopy (TEM).

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The production of bioplastics from marine microorganisms is significantly relevant in the field of biotechnological applications for sustainable ecological management. Nevertheless, the expense associated with PHB production is substantial and regarded as the primary obstacle to its industrialization. In this study, orange peel waste served as a carbon source to enhance PHB production efficiency.

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Sulfated polysaccharides (SPS) derived from seaweeds are precious bioactive compounds of diverse biological activities. Fucoidan is a complex SPS composed of L-fucose and sulfate groups, can be extracted from brown seaweeds, as well as microbial, insect, plant glycans, and marine invertebrates. It has gained considerable attention due to its anti-inflammatory, anticancer, antiviral, antithrombotic, hypolipidemic, and immune-modulatory properties.

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Fusarium wilt causes destructive effects on Vicia faba (VF). This study is innovative because it evaluates the comparative effects of various biological treatments on different VF cultivars to determine the therapeutic potential of each treatment against Fusarium wilt. In this study, the suppression of F.

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Introduction: Clinical isolates of () are among the most recovered bacteria with phenotypic antimicrobial resistance. Bimetallic nanoparticles (BNPs) have received much attention for antimicrobial activity in the last decade. This research aimed to biosynthesize bimetallic copper oxide-selenium nanoparticles (CuO-Se BNPs) and to assess its bioactivity on various clinical isolates.

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The Editorial Office retracts the article "Mycosynthesis of Hematite (α-FeO) Nanoparticles Using and Their Antimicrobial and Photocatalytic Activities" [...

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Trimetallic nanoparticles (TMNPs) have emerged as a pivotal area of research due to their unique properties and diverse applications across medicine, agriculture, and environmental sciences. This review provides several novel contributions that distinguish it from existing literature on trimetallic nanoparticles (TMNPs). Firstly, it offers a focused exploration of TMNPs, specifically addressing their unique properties and applications, which have been less examined compared to other multimetallic nanoparticles.

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Monoclonal antibodies (mAbs) are a key class of biotherapeutic medicines used to treat a wide range of diseases, such as cancer, infectious diseases, autoimmune disorders, cardiovascular diseases, and hemophilia. They can be engineered for greater effectiveness and specific applications while maintaining their structural elements for immune targeting. Traditional immunoglobulin treatments have limited therapeutic uses and various adverse effects.

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Oleaginous yeasts are considered promising sources for lipid production due to their ability to accumulate high levels of lipids under appropriate growth conditions. The current study aimed to isolate and identify oleaginous yeasts having superior ability to accumulate high quantities of lipids; and enhancing lipid production using response surface methodology and repeated-batch fermentation. Results revealed that, twenty marine oleaginous yeasts were isolated, and the most potent lipid producer isolate was Candida parapsilosis Y19 according to qualitative screening test using Nile-red dye.

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In this study, a nanocomposite based on copper oxide-zinc oxide nanoparticles and Gum Arabic (GA@CuO-ZnO nanocomposite) was successfully synthesized using green method. Characterization results revealed that the prepared nanocomposite appeared at the nanoscale level, showed excellent dispersion, and formed stable colloidal nano-solutions. The bimetallic GA@CuO-ZnO nanocomposite was evaluated for its anticancer, antibacterial, and antifungal properties.

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Cancer and microbial infections place a significant burden on the world's health systems and can increase the rate of disease and mortality. In the current study, a novel nanocomposite based on Gum Arabic, silver and copper oxide nanoparticles (GA@Ag-CuO nanocomposite) was synthesized to overcome the problem of microbial infection and in cancer treatment. Characterization using UV-Vis.

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Article Synopsis
  • The study focused on antimicrobial resistance in carbapenem-resistant clinical isolates and their ability to produce biofilms and various resistance enzymes.
  • About 50% of the isolates were multidrug-resistant, with 98.4% producing extended-spectrum β-lactamases and significant levels of biofilm production.
  • The presence of multiple resistance genes was common, indicating a high prevalence of antimicrobial resistance mechanisms, which may contribute to the emergence of multidrug-resistant phenotypes.
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An advanced hybrid nanocomposite based on different metals (copper, cobalt, and chromium) decorated with sustainable polysaccharides (gelatin, GLN, and hydroxyethyl cellulose, HEC) was developed. The composite reflects several advantages including a controlled particle size, particle size distribution, along with promising antimicrobial and anticancer activities. Topographical and elemental analyses were carried out using field-emission scanning electron microscopy (FE-SEM), high-resolution transmission electron microscopy (HR-TEM), and energy dispersive X-ray analysis (EDX), demonstrating the formation of trimetallic nanoparticles (NPs) possessing domain sizes of 169 nm and 102 nm assigned to the free nanocomposite (Fcomp) and loaded nanocomposite (Lcomp), respectively.

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The anticancer, antimicrobial, and insecticidal activities of sarcotrocheliol (1) and cholesterol (2) obtained from the soft coral Sarcophyton trocheliophorum (S. trocheliophorum) were intensively studied. According to this study, both compounds 1 and 2 showed potential cytotoxicity towards the human colorectal carcinomaHCT-116 (IC 10.

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The main objective of this study was to evaluate the biological activities of Anabasis setifera extract, including its antimicrobial, anticancer, and antioxidant properties. In the current study, Anabasis setifera leaves extract was evaluated for antimicrobial, anticancer, antioxidant activities and phytochemical analyses. Ethyl acetate extract of Anabasis setifera (EA-AS) exhibited promising antimicrobial activity toward Escherichia coli, Staphylococcus aureus, Salmonella typhimurium, Bacillus subtilis, Candida albicans, Aspergillus brasiliensis, Aspergillus fumigatus with MICs 62.

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Commonly used antimicrobial agents are no longer effective due to their overuse or misuse. In addition, many medicinal plant extracts can combat infectious diseases due to their main active constituents or secondary metabolites. The current study aimed to assess the bioactivities of (LN) leaf extract (LE) against different multi-drug resistant (MDR) () isolates.

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Article Synopsis
  • Plant growth-promoting bacteria (PGPB) can enhance crop yield and nutrition, with this study focusing on their effects on dwarf castor beans following legumes and grasses in Brazil.
  • The research tested various nitrogen (N) application rates alongside PGPB inoculation, finding significant increases in grain and oil yields at specific N rates, especially with inoculation treatments.
  • The findings suggest that combining optimal N rates with PGPB inoculation can lead to higher castor bean yields while reducing fertilizer use, promoting more sustainable agricultural practices.
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