Assessment of Preferred Interview Format Among 2025 Urology Residency Match Applicants.

Objective: The Society of Academic Urologists (SAU) made no definitive recommendation on interview format for the 2025 urology match. The purpose of this study was to survey applicants for this cycle regarding preferences and perceptions related to interview format.

Methods: As part of a prospective assessment, surveys were administered to all applicants to our urology residency program for the 2025 cycle, both before interview and following the match process.

Potential reproductive impairment due to Solanum glaucophyllum-induced calcinosis in female ruminants.

Solanum glaucophyllum is a toxic calcinogenic plant endemic to Central Argentina and is widely recognized as the primary cause of enzootic calcinosis in ruminants. Although the systemic calcification induced by this plant is well documented, its potential impact on reproductive performance remains underexplored. The present study reports the first evidence of calcinosis affecting the female reproductive organs of ruminants.

Machine Learning-Based Identification of Risk Factors for ICU Mortality in 8902 Critically Ill Patients with Pandemic Viral Infection.

: The SARS-CoV-2 and influenza A (H1N1)pdm09 pandemics have resulted in high numbers of ICU admissions, with high mortality. Identifying risk factors for ICU mortality at the time of admission can help optimize clinical decision making. However, the risk factors identified may differ, depending on the type of analysis used.

Meropenem and piperacillin/tazobactam optimised dosing regimens for critically ill patients receiving renal replacement therapy.

Purpose: Optimal dosing of meropenem and piperacillin/tazobactam in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to variable pharmacokinetics. We aimed to develop generalisable optimised dosing recommendations for these antibiotics.

Methods: Prospective, multinational pharmacokinetic study including patients requiring various forms of RRT.

Albumin Enhances Microvascular Reactivity in Sepsis: Insights from Near-Infrared Spectroscopy and Vascular Occlusion Testing.

: In septic shock, microcirculatory dysfunction contributes to organ failure and mortality. While sidestream dark-field (SDF) imaging is the reference method for assessing microvascular perfusion, its complexity limits routine use. This study evaluates near-infrared spectroscopy (NIRS) with vascular occlusion testing (VOT) as a potential bedside tool for monitoring microcirculatory changes following fluid resuscitation.

Combining Predictive Models of Mortality and Time-to-Discharge for Improved Outcome Assessment in Intensive Care Units.

The Patient Outcome Assessment and Decision Support (PADS) model is a real-time framework designed to predict both mortality and the likelihood of discharge within 48 h in critically ill patients. By combining these predictions, PADS enables clinically meaningful stratification of patient trajectories, supporting bedside decision-making and the planning of critical care resources such as nursing allocation and surgical scheduling. PADS integrates routinely collected clinical data: SOFA variables, age, gender, admission type, and comorbidities.

Longitudinal analysis of lung microbiome, immune response, and metabolism in ventilator-associated pneumonia: a cohort study.

Rationale:  Ventilator-associated pneumonia (VAP) is a common complication in patients under invasive mechanical ventilation (IMV), yet its underlying mechanisms remain poorly understood. This study investigated the lung microbiome, inflammatory response, and metabolism in patients undergoing IMV to identify factors that may predispose them to developing VAP.

Objectives: To investigate how changes in lung microbiome composition, inflammatory response, and metabolic profiles may predispose patients undergoing IMV to develop VAP.

Does Empirical Antibiotic Use Improve Outcomes in Ventilated Patients with Pandemic Viral Infection? A Multicentre Retrospective Study.

During the influenza A(H1N1) and COVID-19 pandemics, empirical antibiotic treatment (EAT) was widely administered to critically ill patients despite low rates of confirmed bacterial co-infection (COI). The clinical benefit of this practice remains uncertain and may contradict antimicrobial stewardship principles. To evaluate whether EAT at ICU admission reduces ventilator-associated pneumonia (VAP) incidence or ICU mortality in critically ill patients with pandemic viral pneumonia, stratified by presence of COI.

A comparison of renal cell carcinoma with tumor thrombus across North America, Central/South America, and South Korea.

Purpose: With multi-institutional collaboration, the purpose of this study was to analyze geographical differences of renal cell carcinoma with tumor thrombus between patients in North America, Central/South America, and South Korea.

Materials And Methods: Patients with renal cell carcinoma and a tumor thrombus who underwent nephrectomy plus thrombectomy were retrospectively analyzed. Patients were from North America, Central/South America, and South Korea.

A comparison of open, laparoscopic, and robotic radical nephrectomy with tumor thrombectomy from the intercontinental collaboration on renal cell carcinoma.

The gold standard treatment for renal cell carcinoma with a tumor thrombus (RCC-TT) is radical nephrectomy with tumor thrombectomy (RN-TT). Operative approaches to this can be done open (ORN-TT), laparoscopic (LRN-TT), or robotic (RRN-TT). The purpose of this study was to compare overall survival (OS), cancer-specific survival (CSS), and metastasis-free survival (MFS) between open, laparoscopic, and robotic approaches to RN-TT using the Intercontinental Collaboration on Renal Cell Carcinoma (ICORCC) database.

Processing of bio-based photocatalytic sponge-like structures containing C,N-TiO colloidally dispersed onto cellulose nanofibers for microplastic remediation.

This study presents an innovative approach for immobilizing a highly efficient photocatalyst on a bio-based matrix derived from biorefinery processing of agricultural biomass. This strategy adds significant value to the lignocellulosic fraction, while reducing the number of unit operations typically required for photocatalyst recovery (e.g.

Management of Intra-Abdominal Candidiasis in Intensive Care Setting: A Narrative Review.

Intra-abdominal candidiasis (IAC), with or without candidemia, is a common condition in patients in intensive care units (ICUs). Early diagnosis of IAC remains a challenge for clinicians despite new biomarkers. Early and appropriate antifungal treatment, which is associated with better clinical outcomes, is negatively affected by the increased isolation of non-albicans strains that are resistant to the commonly used azoles and echinocandins.

Outcomes and Predictors of Mortality in Patients with Severe COVID-19 and COPD admitted to ICU: A multicenter study.

Background: High mortality rates among patients with chronic obstructive pulmonary disease (COPD) admitted to intensive care units (ICUs) during the COVID-19 pandemic highlight the need for tailored clinical management strategies.

Study Design And Methods: Epidemiological, clinical, and laboratory data were collected in REDCap for 6,512 patients hospitalized with COVID-19 across 55 Spanish ICUs. Patients were stratified into three groups: those with COPD, those with other chronic respiratory diseases (CRD), and those without respiratory comorbidities (No CRD).

Postoperative complications, emergency department utilisation, and readmission after radical cystectomy.

Introduction: There is minimal research on the types of complications patients experience after radical cystectomy (RC). Moreover, the impact of these complications is not well qualified. The primary purpose of this study is to qualify complications after RC and quantify rates of emergency department (ED) utilisation and readmissions to the hospital.

Severe community-acquired pneumonia (sCAP): advances in management and future directions.

Severe community-acquired pneumonia (sCAP) is a major global health challenge, with high morbidity and mortality, especially among patients requiring intensive care. Despite advancements in antimicrobial therapies and supportive care, sCAP remains a significant threat, particularly for those needing invasive mechanical ventilation or vasopressor support. Recent progress in diagnostics, therapeutics and management strategies offers hope for improved outcomes.

Acidification affects the early development of Colombian endemic fish Prochilodus magdalenae.

There is a significant knowledge gap regarding the acidification of freshwater ecosystems and its effects on biological systems. The bocachico (Prochilodus magdalenae), an endemic and migratory species vital to Colombia's inland fisheries, is currently classified as vulnerable. This study evaluated the impact of different pH levels (6.

Nosocomial lower respiratory tract infections in patients with immunosuppression: a cohort study.

Background: This post-hoc analysis of a multinational, multicenter study aimed to describe and compare clinical characteristics, microbiology, and outcomes between immunosuppressed and non-immunosuppressed patients with nosocomial lower respiratory tract infections (nLRTI). The study utilized data from the European Network for ICU-related Respiratory Infections, including 1,060 adult ICU patients diagnosed with nLRTI. Descriptive statistics were used to compare baseline characteristics and pathogen distribution between groups.

Pancreatic Cancer Solitary Metastasis to Colon is a Rare Entity.

Metastases in pancreatic ductal adenocarcinoma are present in over 50% of cases at the time of diagnosis, with the liver, peritoneum, and lung being some of the most common sites. By contrast, solitary distant metastasis to the colon is a rare entity but clinically significant. We report 2 cases of synchronous pancreatic ductal adenocarcinoma distant metastasis to colon along with a literature review.

Lignin micro/nanoparticles from alternative biomass sources for neutral-pH Pickering emulsions and quercetin encapsulation.

Conventional Pickering Emulsions (PEs) stabilizers are often petrochemical-based, raising concerns about bioincompatibility and adverse reactions. Using sustainable biomass, such as pruning residues, offers potential for natural PEs stabilizers development. This study explores the use of avocado pruning lignin (APL), alongside various commercial lignins, to produce natural stabilizers for neutral-pH PE.

Effects of an eCG-like glycoprotein treatment and nutritional status on reproductive performance in suckled beef cows subjected to a progesterone-based 7-d Co-Synch protocol.

The objective of the present study was to evaluate the effects of a synthetic eCG-like glycoprotein treatment, body condition score changes, and postpartum nutritional supplementation on follicular and luteal characteristics and pregnancy rates in suckled beef cows synchronized with a 7-d Co-Synch protocol. In Experiment I, 1218 suckled cows received a progesterone intravaginal device (1.0 g; IVD) and 100 μg GnRH on Day -10.

Hemicellulose/PVA-based bioactive films for food packaging: Effect of the molecular weight of avocado pruning waste-derived hemicellulose on biocomposite properties.

The rising demand for sustainable packaging and urgent need for circular strategies in the agri-food sector motivate exploring biopolymer packaging from agri-food by-products. This study presents an efficient method for utilizing avocado pruning waste (APW) by extracting hemicelluloses for polyvinyl-alcohol (PVA)-based food packaging films. Autohydrolysis and tangential-flow diafiltration produced hemicellulose fractions with varying molecular weights: >50, 50-8, 8-1, and 1 kDa.

Inverse Design of an All-Dielectric Nonlinear Polaritonic Metasurface.

Nonlinear metasurfaces offer the ability to realize optical nonlinear devices with unparalleled properties compared to nonlinear crystals, due to the interplay between photonic resonances and materials properties. The complicated interdependency between efficiency and emission directionality of the nonlinear optical signal on the existence, localization, and lifetimes of photonic resonances, as well as on the nonlinear susceptibility, makes it extremely difficult to design optimal metasurfaces using conventional materials and geometries. Inverse design using topology optimization is a powerful design tool for photonic structures, but traditional approaches developed for linear photonics are not suitable for such high dimensional nonlinear problems.